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The role of phospholipase A2 in mast cell activation

The role of phospholipase A2 in mast cell activation

... on mast cell activation have been ...of mast cell activation by PLA 2 ...platelets, mast cells and inflammatory ... See full document

308

Regulatory role of cytosolic phospholipase A2 alpha in the induction of CD40 in microglia

Regulatory role of cytosolic phospholipase A2 alpha in the induction of CD40 in microglia

... Sodium azide, trypan blue, p-nitrophenylphosphate, phenylmethylsulfonyl fluoride, leupeptin, benzamidine, aprotinin, DMSO, Tween 20, Tris, 4,6-diamidino-2- phenylindole (DAPI), bovine serum albumin (BSA), Trypsin-EDTA, ... See full document

16

Cytosolic phospholipase A2 plays a crucial role in ROS/NO signaling during microglial activation through the lipoxygenase pathway

Cytosolic phospholipase A2 plays a crucial role in ROS/NO signaling during microglial activation through the lipoxygenase pathway

... major role in the progression of neurodegenerative diseases including Alzheimer’s dis- ease, Parkinson’s diseases, cerebral vascular stroke, and in- fectious HIV ...microglial activation was proven a vi- ... See full document

20

Clinical and biological role of secretory phospholipase A2 in acute respiratory distress syndrome infants

Clinical and biological role of secretory phospholipase A2 in acute respiratory distress syndrome infants

... ARDS in infants differs from the syndrome in adults in terms of epidemiology, triggering causes and prognosis [7], thus requires specific additional research [8]. Since sPLA2 is responsible for surfactant catabolism, its ... See full document

12

The Role of Asymmetric Dimethylarginine and Lipoprotein Associated Phospholipase A2 in Children and Adolescents with Dyslipidemia

The Role of Asymmetric Dimethylarginine and Lipoprotein Associated Phospholipase A2 in Children and Adolescents with Dyslipidemia

... pivotal role in the atherosclerotic process and development, the investigation of biomarkers involved in the pathophysiologic mechanisms of subclinical vascular disease such as ADMA and Lp-PLA2 is of great ... See full document

8

Mutational Analysis of Narrow Pores at the Fivefold Symmetry Axes of Adeno-Associated Virus Type 2 Capsids Reveals a Dual Role in Genome Packaging and Activation of Phospholipase A2 Activity

Mutational Analysis of Narrow Pores at the Fivefold Symmetry Axes of Adeno-Associated Virus Type 2 Capsids Reveals a Dual Role in Genome Packaging and Activation of Phospholipase A2 Activity

... the cell but also combines a number of functional elements which are needed for host cell recognition, intracellular trafficking, and disassembly in order to successfully deliver genetic information to the ... See full document

13

Study of the Activity of Phospholipase A2 in Venom of the Transcaucasian Macrovipera Lebetina Obtusa

Study of the Activity of Phospholipase A2 in Venom of the Transcaucasian Macrovipera Lebetina Obtusa

... physiological role might not be restricted to protection against PLA2 toxins, but could be extended to other functions, as in the innate immune system and local regulation of PLA2s ... See full document

6

Mast cell activation and clinical outcome in pediatric cholelithiasis and biliary dyskinesia

Mast cell activation and clinical outcome in pediatric cholelithiasis and biliary dyskinesia

... or activation and the ejection fraction although this may be the result of the sensitiv- ity of the method ...The activation index is a general indicator of activation but may be limited in assessing ... See full document

8

Cytosolic phospholipase A2 in hypoxic pulmonary vasoconstriction

Cytosolic phospholipase A2 in hypoxic pulmonary vasoconstriction

... Cytosolic phospholipase A 2 (cPLA 2 ) releases arachidonic acid (AA) from phospholipids in cell ...the role of cPLA 2 in hypoxic pulmonary vasoconstriction (HPV), we measured the increase in left ... See full document

9

The rapid and reversible activation of a calcium independent plasmalogen selective phospholipase A2 during myocardial ischemia

The rapid and reversible activation of a calcium independent plasmalogen selective phospholipase A2 during myocardial ischemia

... potential role of these calcium-independent phospholipases A2 in mediating membrane dysfunction during early myocardial ischemia, the temporal course of alterations ... See full document

6

A signalling cascade involving receptor-activated phospholipase A2, glycerophosphoinositol 4-phosphate, Shp1 and Src in the activation of cell motility

A signalling cascade involving receptor-activated phospholipase A2, glycerophosphoinositol 4-phosphate, Shp1 and Src in the activation of cell motility

... to cell motility. GroPIns4P is also likely to play an important role in other cell responses such as the immuno-inflammatory response [9], depending on the cell type involved or on specific ... See full document

21

Regulation of human eosinophil degranulation and activation by endogenous phospholipase A2

Regulation of human eosinophil degranulation and activation by endogenous phospholipase A2

... pathogenetic role in asthma and in the defense against parasitic ...endogenous activation of phospholipase ...Eosinophil activation was initiated in vitro with 10(-6) M FMLP and 5 ... See full document

9

Effect of common food additives on mast cell activation

Effect of common food additives on mast cell activation

... central role in the genesis and modulation of allergic and infl ammatory ...between mast cells and the most common additives approved for use in ...on mast cell degranulation were carried out. ... See full document

5

Mast cell activation disease: a concise practical guide for diagnostic workup and therapeutic options

Mast cell activation disease: a concise practical guide for diagnostic workup and therapeutic options

... shown to be as efficacious as, and less toxic than the non-PEGylated form in some chronic myeloproliferative diseases, but it has not been specifically studied in MCAD. 2-Chlorodeoxyadenosine (2-CdA) is generally ... See full document

8

Phospholipase A2 is involved in galactosylsphingosine induced astrocyte toxicity, neuronal damage and demyelination

Phospholipase A2 is involved in galactosylsphingosine induced astrocyte toxicity, neuronal damage and demyelination

... psychosine-induced cell death ...(with phospholipase A2 involvement) under ROS condi- tions [48, ...a role in psychosine-induced toxicity in oligodendrocytes [9] and highlights possible ... See full document

19

Involvement of proteases and kinases in mast cell activation

Involvement of proteases and kinases in mast cell activation

... the mast cell, inducing cross-linking and FcgRI receptor ...the cell membrane, and then directly activate a pertussis toxin sensitive G protein to allow an increase in PLC a c t i v i t y C a l c i u ... See full document

254

Regulation of arachidonic acid, eicosanoid, and phospholipase A2 levels in murine mast cells by recombinant stem cell factor

Regulation of arachidonic acid, eicosanoid, and phospholipase A2 levels in murine mast cells by recombinant stem cell factor

... The current study evaluates the capacity of recombinant rat stem cell factor (rrSCF) to regulate enzymes that control AA release and eicosanoid generation in mouse bone marrow-derived mast cells (BMMCs). ... See full document

9

The Inhibitory Effects of Tetracycline on Mastocytosis

The Inhibitory Effects of Tetracycline on Mastocytosis

... j774 cell macrophage is a characte- ristic that has been shown by most CMTs, which is similar to what is achieved bybroad-spectrum antibiotics, doxycycline and ...dual role of being a physiological ... See full document

26

Interferon gamma induces the synthesis and activation of cytosolic phospholipase A2

Interferon gamma induces the synthesis and activation of cytosolic phospholipase A2

... bromophenacyl bromide (10(-5) M). Calcium ionophore A23187 (10(-5) M) further increased the [3H]AA release from the IFN-gamma-treated cells. Subcellular enzyme activity assay revealed that IFN-gamma increased PLA2 ... See full document

8

Role Of Mast Cell In Oral Pathology

Role Of Mast Cell In Oral Pathology

... cause mast cell RANTES ...Thus mast cell can promote degranulation and tissue remodeling & is inflammation in the absence of IgE mediated considerd an important angiogenic ...factor. ... See full document

6

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