[PDF] Top 20 Role of β1 integrin in epidermal development and homeostasis
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Role of β1 integrin in epidermal development and homeostasis
... To date, at least 12 proteins have been shown to bind to p i integrin tails. They include talin (Horwitz et al., 1986), a actinin (Otey and Burridge, 1990), filamin (Pavalko et al., 1989), ILK (Hannigan et al., ... See full document
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Epithelial β1 integrin is required for lung branching morphogenesis and alveolarization
... 1 integrin is the major isoform of the eight β -integrin subunits, and is the β -integrin subunit present in 12 of the 24 known α - β integrin heterodimers (Pozzi and Zent, ...1 ... See full document
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The Role of CDK4 in Epidermal Stem Cell Homeostasis and Skin Tumorigenesis.
... Murine epidermal stem cells have been classified by a strong expression of β1, α6 integrin (CD49f), Keratin15 (K15), CD34, Lgr5, MTS24, Lgr6, Blimp1 and Lrig1 (Liu, Lyle et ...and β1 ... See full document
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β1 integrins activate a MAPK signalling pathway in neural stem cells that contributes to their maintenance
... that β1 integrins regulate neural stem cell behaviour within the CNS niche leads us to question the nature of the ligands recognised by these ...four β1 integrins, α1β1, α3β1, α6β1 and ...of ... See full document
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Deregulation of the pRb-E2F4 axis alters epidermal homeostasis and favors tumor development
... in epidermal homeostasis, proliferation, differentiation and tumor development (reviewed in Costa et al ...inducible epidermal loss of Rb1 (Rb f/f ;K14creER TM ;p107 -/- or Rb f/f ;K14creER TM ... See full document
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Integrin function and regulation in development
... of development Information on the spatio-temporal expression of integrins are crucial to investigate their role in ...identify integrin subunits in mouse or ...several integrin heterodimers ... See full document
7
β1 and β4 integrins: from breast development to clinical practice
... important role of the ECM receptors, integrins being the prime ...– integrin axis regulates many crucial cellular functions including survival, migration and quiescence; the imbalance in any of these ... See full document
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Talin regulates integrin β1 dependent and independent cell functions in ureteric bud development
... crucial role in regulating the actin cytoskeleton of CD cells (Albiges-Rizo et ...major role in the formation of cadherin-mediated cell-cell adhesions (Zhang et ...a role in endothelial barrier ... See full document
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Atomic Force Microscopy Based Nanoscopy of Chondrogenically Differentiating Human Adipose Derived Stem Cells: Nanostructure and Integrin β1 Expression
... particular, integrin family members ...important role in tissue homeostasis, and that the ECM regulates ...tissue development, and ...of integrin β1 is connected to the SOX ... See full document
11
Collagen VII plays a dual role in wound healing
... the role of the cell microen- vironment in tissue repair remains ...the role of the basement membrane protein collagen VII (COL7A1) in wound ...of integrin α6β4 in basal keratinocytes and negatively ... See full document
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Relative roles of TGF-β and IGFBP-5 in idiopathic pulmonary fibrosis
... the development of pulmonary fibrosis ...therapeutic role of FGF-1 should be defined in IPF, as inhibiting TGF-β globally may have adverse effects on its role in tissue ... See full document
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β1 integrins signaling and mammary tumor progression in transgenic mouse models: implications for human breast cancer
... ligands, β1-integrins play a critical role in the main- tenance of mammary tissue integrity ...gland development as well as for mammary epithelial cell diff erentiation [42- ...Moreover, ... See full document
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β1 integrin is a crucial regulator of pancreatic β cell expansion
... of β1 integrin in β- cells can dramatically alter their ability to respond to growth stimuli provided by ECMs and growth factors, both in vivo and in ...of β1 integrin, whereas the ... See full document
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Fetuin A: A Newer Marker for Pre Diabetes
... potential role of fetuin A in regulation of glucose metabolism is its correlation with inheritance pattern as the gene encoding for fetuin A has been found to be located on chromosome 3q27, the region that was ... See full document
7
Sharpin suppresses β1-integrin activation by complexing with the β1 tail and kindlin-1
... the integrin α CT and can suppress both β1- and β2-integrin activation by block- ing recruitment of talin and kindlin [32, 36, ...the role of sharpin in inhibiting integrin activa- tion ... See full document
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β1 Integrin Mediates Internalization of Mammalian Reovirus
... Cells, viruses, and antibodies. Spinner-adapted murine L929 (L) cells were grown in either suspension or monolayer cultures in Joklik’s modified Eagle’s minimal essential medium (Irvine Scientific, Santa Ana, CA) ... See full document
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Role of Microfinance in Micro Entrepreneurship Development in Bangladesh: Prospects and Challenges
... Analyzing the loan history of the respondents, this research found that the MFI plays an important role in scaling up the enterprise through ensuring continuous capital flow to the business by providing credit ... See full document
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Integrin expression during epidermal morphogenesis and wound healing
... This integrin has been show n to bind to collagen types 1-lV (Kramer and M arks 1989; Belkin et al, 1990; Defilippi et al, 1991b), and to the E l region of lam inin (Ignatius and Reichardt 1988; Hall et al, ... See full document
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Macrolide analog F806 suppresses esophageal squamous cell carcinoma (ESCC) by blocking β1 integrin activation
... of β1 integrin activity by immunoprecipitation was performed as described previously [45, ...anti-active β1 integrin (CHEMICON International, ... See full document
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Integrin suppresses neurogenesis and regulates brain tissue assembly in planarian regeneration
... cells were elevated in β 1-integrin(RNAi) animals at 7 days of regeneration compared with control RNAi animals (Fig. 5C,D). At this time in regeneration, β 1-integrin(RNAi) animals had similar numbers of ... See full document
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