[PDF] Top 20 Safety and efficacy of venoplasty in MSA randomized, double-blind, sham-controlled phase II trial
Has 10000 "Safety and efficacy of venoplasty in MSA randomized, double-blind, sham-controlled phase II trial" found on our website. Below are the top 20 most common "Safety and efficacy of venoplasty in MSA randomized, double-blind, sham-controlled phase II trial".
Safety and efficacy of venoplasty in MSA randomized, double-blind, sham-controlled phase II trial
... the sham and venoplasty groups on the PROs throughout the 48 ...the sham intervention or in the number of participants who had objective evidence of new inflammatory activity (MRI CUA lesion and/or ... See full document
10
Novel oral targeted therapies in inflammatory bowel disease
... the safety and efficacy of a JAK 1 inhibitor upadacitinib (ABT-494; AbbVie, Illinois, United States) in CD patients who had inadequate response or intolerant of immunomodulators or anti- TNF therapy in a ... See full document
37
Everolimus in the treatment of subependymal giant cell astrocytomas, angiomyolipomas, and pulmonary and skin lesions associated with tuberous sclerosis complex
... therapeutic efficacy and safety of everolimus have been demonstrated in multicenter, international, randomized, double-blind, placebo-controlled ...long-term safety and ... See full document
11
Overview of meropenem-vaborbactam and newer antimicrobial agents for the treatment of carbapenem-resistant <em>Enterobacteriaceae</em>
... two Phase III trials, Targeting Antibiotic Non-susceptible Gram-negative Organisms (TANGO)-I and ...international Phase III, randomized, double-blind, double-dummy, ... See full document
12
Topical application of Jaungo in atopic dermatitis patients: study protocol for a randomized, controlled trial
... a randomized, double-blind, placebo-controlled, single-center, phase IIa clinical trial to investigate the safety, preliminary efficacy, and dose response of Jaungo ... See full document
8
A phase IIa proof of concept, placebo controlled, randomized, double blind, crossover, single dose clinical trial of a new class of bronchodilator for acute asthma
... testing and their safety profiles are well documented [9, 19, 20]. Subjects receiving S1226 reported more AEs than those receiving the placebo, but these were mild in severity, they were transient, and the ... See full document
8
A double blind randomized placebo controlled phase I/II study assessing the safety and efficacy of allogeneic bone marrow derived mesenchymal stem cell in critical limb ischemia
... The Investigational Medicinal Product (IMP) was BM- MSCs which obtained from bone marrow aspirates from healthy donors who were not HLA matched to the re- cipients. The volunteers for bone marrow donation were tested ... See full document
11
The EFFECT trial: evaluating exacerbations, biomarkers, and safety outcomes with two dose levels of fluticasone propionate/formoterol in COPD
... Treatment) trial is a Phase III, 52-week, randomized, double-blind study to evaluate the efficacy and safety of two doses of fluticasone propionate/formoterol compared to ... See full document
8
A phase II, sham controlled, double blinded study testing the safety and efficacy of the coronary sinus reducer in patients with refractory angina: study protocol for a randomized controlled trial
... COSIRA trial is a phase II trial and several limitations inherent in this type of study must be ...COSIRA trial was primarily designed to test whether the Reducer can improve symptoms ... See full document
10
A randomized, double blind, multicenter, placebo controlled phase III trial to evaluate the efficacy and safety of pregabalin in Japanese patients with fibromyalgia
... this trial (16) than in previous trials of 450 mg/day pregabalin in FM patients (in which it ranged from 9 to 11) [10,13,14], potentially influenced by the somewhat flexible, lower dosing in this ...proven ... See full document
10
Safety and efficacy of PG102P for the control of pruritus in patients undergoing hemodialysis (SNUG trial): study protocol for a randomized controlled trial
... multicenter, randomized, double-blind, placebo- controlled trial in which one group will be treated with PG102P ...superiority trial is planned to test the hypothesis that PG102P ... See full document
7
Gabapentin enacarbil for the treatment of moderate to severe primary restless legs syndrome (Willis-Ekbom disease): 600 or 1,200 mg dose?
... open-label trial (XP055), patients were treated first with gabapentin enacarbil 1,200 mg once daily and then, as in clinical practice, given the choice to increase to 1,800 mg or decrease to 600 mg throughout the ... See full document
14
Alogliptin in combination with metformin and pioglitazone for the treatment of type 2 diabetes mellitus
... 26-week, randomized, double-blind, placebo-controlled study included patients with an A1c of ...were randomized to receive metformin plus placebo, alogliptin ...select efficacy ... See full document
12
B-cell-targeted therapies in systemic lupus erythematosus and ANCA-associated vasculitis: Current progress.
... two Phase III trials after the success of Phase IIb EMBLEM ...of safety, the incidence rates of serious adverse events (SAEs) and infusion reactions were comparable across all arms and were not dose- ... See full document
43
Advances in the treatment of relapsing–remitting multiple sclerosis – critical appraisal of fingolimod
... in clinical practice, DMDs or immunosuppressive treat- ments are frequently associated with suboptimal response in terms of efficacy. The existing medications are only partially effective in halting MS relapses ... See full document
13
Delafloxacin: design, development and potential place in therapy
... Quinolones are one of the few families of completely synthetic antibiotics, which have allowed many structural modifications on pharmacophore core to increase their potency, enhance their pharmacokinetic properties and ... See full document
11
Rucaparib: a novel PARP inhibitor for <em>BRCA</em> advanced ovarian cancer
... ARIEL 2 (NCT01891344) is a multicenter, two-part Phase II open-label study assessing rucaparib in relapsed/progressive high-grade serous or endometrioid ovarian carcinoma. Part 1 enrolled patients with ... See full document
13
Role of collagenase clostridium histolyticum in Peyronie's disease
... Injection site bruising, edema, and pain were all com- mon in those patients receiving CCH therapy, occurring in 86.5%, 45%, and 52.3% of the patients, respectively. This proved to be statistically significant in ... See full document
10
The Efficacy and Safety of On-demand Tramadol and Paroxetine Use in Treatment of Life Long Premature Ejaculation: A Randomized Double-blind Placebo-controlled Clinical Trial
... Methods: In this randomized, double-blind, placebo-controlled clinical trial, 150 pa- tients were divided into 3 groups. One group was treated with tramadol 50 mg on- demand, the other ... See full document
6
Quetiapine versus haloperidol in the treatment of delirium: a double-blind, randomized, controlled trial
... extrapyramidal side effects were assessed by using the MSAS. The MSAS is a 5-point scale of nine items (arm dropping, shoulder shaking, elbow rigidity, wrist rigidity, leg pendulousness, head dropping, glabellar tap, ... See full document
11
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