[PDF] Top 20 SaMpling Antibiotics in Renal Replacement Therapy (SMARRT): an observational pharmacokinetic study in critically ill patients
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SaMpling Antibiotics in Renal Replacement Therapy (SMARRT): an observational pharmacokinetic study in critically ill patients
... septic critically ill pa- tients with AKI receiving RRT are likely to be inad- ...This study is the first multi-national obser- vational PK study aimed at determining the important factors ... See full document
8
The optimal timing of continuous renal replacement therapy according to the modified RIFLE classification in critically ill patients with acute kidney injury: a retrospective observational study
... that renal function was more rap- idly recovered and less frequency of catheter related blood stream infections occurred in late RRT initiation ...[7]. Patients with higher creatinine may undergo earlier ... See full document
7
Interventions to prevent hemodynamic instability during renal replacement therapy in critically ill patients: a systematic review
... prospective observational studies of relative blood volume monitoring in the AKI population on IHD did not find any significant concordance be- tween blood volume monitoring and hypotension [2, ...an ... See full document
11
Cefepime dosing regimens in critically ill patients receiving continuous renal replacement therapy: a Monte Carlo simulation study
... simulation study applying MCS tech- nique to evaluate cefepime dosing regimens for manage- ment of ...in critically ill patients. Pharmacokinetic parameters collected from previously ... See full document
11
Fluid balance, intradialytic hypotension, and outcomes in critically ill patients undergoing renal replacement therapy: a cohort study
... the observational nature of this study include the lack of standardised cri- teria for the initiation of and management of RRT, leading to fluid overload as the primary indication for RRT in some ... See full document
10
A proposed algorithm for initiation of renal replacement therapy in adult critically ill patients
... retrospective study of 5,383 critically ill patients, Hoste and colleagues [3] found that of those developing RIFLE class R, 56% progressed to either class I or F, and of those developing ... See full document
8
Early versus late initiation of renal replacement therapy in critically ill patients with acute kidney injury (The ELAIN Trial): study protocol for a randomized controlled trial
... in critically ill patients and despite multiple trials and observational studies, the optimal timing for initiation of renal replacement therapy is still ...of ... See full document
11
Delivered dose of renal replacement therapy and mortality in critically ill patients with acute kidney injury
... IRRT patients, we were unable to correlate out- come with the measured Kt/V, as the necessary laboratory parameters for the calculation were not collected as part of routine ...septic patients, is rou- ... See full document
14
Beta lactam dosing in critically ill patients with septic shock and continuous renal replacement therapy
... the study population of crit- ically ill patients with septic shock in order to avoid vari- ability derived from pathophysiological conditions other than septic ... See full document
16
Earlier versus later initiation of renal replacement therapy among critically ill patients with acute kidney injury: a systematic review and meta-analysis of randomized controlled trials
... and study design. In summary, while the observational stud- ies tended to show more beneficial effects for earlier RRT, clinical trials were unable to replicate these findings ...AKIKI study group ... See full document
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Effectiveness of pharmacist dosing adjustment for critically ill patients receiving continuous renal replacement therapy: a comparative study
... for patients receiv- ing CRRT, and 212 ...whereas antibiotics (n=168, ...per critically ill patient receiving ...27 patients versus [vs] 18 in eleven patients, ... See full document
8
Complications of continuous renal replacement therapy in critically ill children: a prospective observational evaluation study
... all patients on starting CRRT: age; weight; sex; diagnosis; severity scores, pediatric risk of mortality (PRISM II) score [9], pediatric index of mortality (PIM I and II) score [10], pediatric logistic organ ... See full document
11
Original Article Serum vancomycin levels in critically ill elderly patients undergoing continuous renal replacement therapy
... the pharmacokinetic parameters of vancomycin in critically ill elderly patients un- dergoing Continuous Renal Replacement Therapy (CRRT) and provide a baseline for dose ... See full document
8
Tigecycline in critically ill patients on continuous renal replacement therapy: a population pharmacokinetic study
... continuous renal replacement therapy (CRRT), but pharmacokinetic data for tigecycline in patients receiving CRRT are ...Eleven patients mainly with intra-abdominal infections ... See full document
7
Renal replacement therapy is an independent risk factor for mortality in critically ill patients with acute kidney injury
... our study, the initiation of RRT was at the discre- tion of the responsible physician, taking into account the rules of good clinical practice in this ...of patients treated with ...AKI patients is ... See full document
9
Nomenclature for renal replacement therapy and blood purification techniques in critically ill patients: practical applications
... “continuous renal replacement therapy”, “dialysis”, “hemofiltration”, “convection”, “diffu- sion”, “ultrafiltration”, “dose”, “blood purification”, “renal support”, “multiorgan dysfunction”, ... See full document
11
Combination of extracorporeal membrane oxygenation and continuous renal replacement therapy in critically ill patients: a systematic review
... for renal placement therapy could be the risk factor for ...our study, additional sensitivity analysis showed no het- erogeneity after the exclusion of two studies that had matched the baseline data ... See full document
11
ICU survival and need of renal replacement therapy with respect to AKI duration in critically ill patients
... of renal recovery on 28-day ICU ...[20]. Renal recovery status was introduced as a time- dependent variable ...except renal one, and nephrotoxic drug administration in the five previous ...in ... See full document
11
Assessment of pharmacokinetic changes of meropenem during therapy in septic critically ill patients
... Sampling was performed within the first 36 hrs after starting antibiotic therapy (early samples) and repeated, whenever possible, in the 5 th or 6 th day of therapy (late samples). Five mL blood ... See full document
7
Paracetamol therapy and outcome of critically ill patients: a multicenter retrospective observational study
... 15,818 patients with 691,348 temperature measurements at 4 ...these patients, 10,046 (64%) received at least 1 g of paracetamol. Patients who received paracetamol had lower in-hospital mortality (10% ... See full document
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