[PDF] Top 20 Single cell analysis of the inner ear sensory organs
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Single cell analysis of the inner ear sensory organs
... the single time point data into a dynamic network, with the assumption that the spectrum of cellular clusters represents an earlier, progenitor cell type at one end, and at the other end, a more ... See full document
10
Axon guidance in the inner ear
... that inner ear sensory organs can attract statoacoustic (SAG) ...intact ear to ease compari- son with results from the ...ectopic sensory patches containing hair cells can be ... See full document
9
Jag1b is essential for patterning inner ear sensory cristae by regulating anterior morphogenetic tissue separation and preventing posterior cell death
... three sensory cristae are formed from the prosensory ...mouse inner ear, previous work has suggested that the anterior and lateral cristae may derive from a common prosensory domain (Morsli et ...a ... See full document
11
Jagged 1 regulates the restriction of Sox2 expression in the developing chicken inner ear: a mechanism for sensory organ specification
... developing inner ear of mouse and chick embryos (Adam et ...prospective sensory domains of the otocyst (Adam et ...all sensory organs ...few cell diameters beyond the Jag1- ... See full document
10
Analysis of Netrin 1 receptors during inner ear development
... the inner edge of a newly formed semicircular ...(H). Analysis of Unc5b expression in sec- tions from wild type (Q) and Ntn1-/- littermate embryos (R) at ...ihc, inner hair cells; ld, lateral ... See full document
7
Computational analysis of mRNA expression profiling in the inner ear reveals candidate transcription factors associated with proliferation, differentiation, and deafness
... hair cell regeneration is not surprising and is currently the focus of active research ...of cell cycle progression (through c-myc [44]), and cognitive development (through FMR1 ...hair cell ... See full document
19
Cilia driven fluid flow as an epigenetic cue for otolith biomineralization on sensory hair cells of the inner ear
... as single pairs at the anterior and posterior poles of the otic vesicle (Riley et ...hair cell tether cilia that are motile, whereas the small cilia are immotile (Colantonio et ... See full document
8
Lack of Rbl1/p107 Effects on Cell Proliferation and Maturation in the Inner Ear
... ontology analysis revealed that, in addition to an overrepresentation of changed genes associated with gene transcription, lack of Rbl1/p107 in the OC at P0 also affected the expression of a number of genes ... See full document
22
Clonal analysis of the relationships between mechanosensory cells and the neurons that innervate them in the chicken ear
... their cell bodies are neurofilament positive (not ...as sensory is based on their location relative to neurofilament-labeled processes ...AP+ sensory cells of this clone are distributed as two major ... See full document
11
Patterning and morphogenesis of the vertebrate inner ear
... 1997). Inner ear analyses of Pax2-/- mutants reveal an early requirement of Pax2 in cochlear duct outgrowth (Torres et ...in sensory hair cells and its expression domain overlaps with the ... See full document
13
Notch signaling in the development of the inner ear
... in sensory patches also express Lunatic fringe (Lfng) (4,31), a homolog of the Fringe protein that has been shown in Drosophila to interact with Notch in cis and make Notch refractory by activation by Serrate ... See full document
199
Establishment of a proneural field in the inner ear
... neuronal cell specification by ap- proximately two days in ...the sensory epithelia of E11- E12 mice embryos (Shailam et ...zebrafish, sensory and neuronal precursors are specified almost about the ... See full document
11
Cell proliferation during the early compartmentalization of the Xenopus laevis inner ear
... central sensory zone of the S47 saccular and utricular epithe- lium ...the sensory patches of the S47 inner ear (Fig. 3, 4B), cell produc- tion studies show that newly replicating cells ... See full document
9
Distinct capacity for differentiation to inner ear cell types by progenitor cells of the cochlea and vestibular organs
... balance organs of the inner ear – the cochlea and vestibular organs – with specialized neurons, sensory HCs and supporting ...neural inner ear compartments in the early ... See full document
13
Retention of progenitor cell phenotype in otospheres from guinea pig and mouse cochlea
... within sensory regions of mature utricles and organ of Corti ...with single supplements, either EGF, bFGF or IGF1 alone, which provided 40 spheres per 10 5 plated ...the inner ear of adult ... See full document
10
Synaptic coupling of inner ear sensory cells is controlled by brevican-based extracellular matrix baskets resembling perineuronal nets
... Since outer hair cells (OHCs) also convey afferent infor- mation via ribbon synapses and in addition receive three to four efferent fibers, we questioned whether brevican, aggrecan, neurocan, HAPLN1, and HAPLN4 as well ... See full document
18
SOX2 is required for inner ear growth and cochlear nonsensory formation before sensory development
... hair cell labeling ...id cell region and some cells in Ko ̈ lliker ’ s organ (Ko, ...entire inner ear anatomy. (E) The area of nonsensory and sensory regions labeled by tdT/SOX2 was ... See full document
14
Adenovirus Vectors Target Several Cell Subtypes of Mammalian Inner Ear In Vivo
... mouse inner ear cell subtypes for gene ...P4 inner ear, with different specificities and expression levels that are dependent on the type of adenoviral vectors and the age of ... See full document
9
Cross regulation of Ngn1 and Math1 coordinates the production of neurons and sensory hair cells during inner ear development
... features in our studies of Math1 expression in the vestibular system of the mouse. Of the two genes relevant to this study, it is Ngn1 and not Math1 that initially marks the prospective maculae and exhibits the ... See full document
11
Apaf1 dependent programmed cell death is required for inner ear morphogenesis and growth
... of cell proliferation, differentiation, and programmed cell ...the cell (reviewed by Sanders and Wride, 1995; Cecconi and Gruss, ...of cell death ... See full document
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