[PDF] Top 20 Skeletal muscle stem cells

... Upon skeletal muscle injury, quiescent satellite cells expressing Pax-7 and Foxk1 are activated to proliferate, up-regulating the myogenic determination factors, MyoD and Myf- 5 [13-17], the myoblast ... See full document

... Skeletal muscle stem cells are resident in all skeletal muscles, but may possess varying prolifera- tive/differentiative capacity, due to location and/or ...Postnatal skeletal ... See full document

... 4414 cells, 217 (5%) revealed a gene expression pattern that could be assigned to ...cluster, cells were observed to express variable levels of the MuSC markers vascular cell adhesion molecule 1 ( Vcam1 ), ... See full document

... Fos), skeletal muscles were fixed immediately in ...unfixed skeletal muscles were minced as described [4]; fixed samples were incubated with collagenase at double the normal concentration, and mRNA was ... See full document

... some muscle types or in pure muscle ...between muscle-derived IL32 levels and whole body insulin sensitivity in humans in ...and muscle growth/ maintenance by inhibiting expression of myogenic ... See full document

... donor stem cells to treat a muscular dystrophy is a mouse model of a human muscular dystrophy, which is also ...in skeletal muscles body- wide and is a much-used model of DMD ...donor stem ... See full document

... satellite cells. Satellite cells have high Notch activity that is required for their maintenance (Bjornson et ...prime muscle stem cells in the dorsal DM to enter the myogenic lineage ... See full document

... Skeletal muscle damaged by injury or by degenerative diseases such as muscular dystrophy is able to regenerate new muscle ...satellite cells, myogenic progenitors localized between the basal ... See full document

... quality. Stem cells have been explored as a possibility to restore the function of seriously damaged livers, based on their self-renewability and multiple differentiation ...derived stem cells ... See full document

... attenuate muscle regeneration in a rabbit muscle strain injury model ...injured muscle by delaying the maturation of regenerat- ing myofibers ...of muscle stem cells and NSAIDs ... See full document

... hAFS cells were detached physically from culture dishes using a cell scrapper and sonicated in RIPA buffer (50 mM Tris–HCl pH 8.0, 150 mM NaCl, 1% NP-40, 0.5% sodium deoxycholate, 0.1% sodium dodecyl sulfate ... See full document

... dystrophic muscle, a few human nuclear lamin A/C–positive cells were distributed near the capillary network (arrows) and regenerating myo- fibers, identified by a centrally located nucleus (blue after DAPI ... See full document

... resident stem cells. Adult stem cells are characterized by the ability to self-renew and differentiate into multiple cell types within a ...that stem cells are nonetheless ... See full document

... alternative stem cells for therapy of muscular dystrophies, which theoretically should benefit from healthy cells regardless of ...ameliorating muscle dystrophy in a canine model, has raised ... See full document

... and skeletal muscle of both irradiated and nonirradiated mice contained similar absolute numbers of donor- derived myonuclei, our experiments suggest that hematopoietic engraftment is not required for ... See full document

... in muscle stem cells in the young and that loss of klotho expression in the aged might be one of the causes for in- creased canonical Wnt signaling in aged muscle stem ...cultured ... See full document

... Skeletal muscle injuries are very frequently present in sports medicine and pose challenging problems in trau- ...trauma, skeletal muscles have the capacity to regenerate and repair in a complex and ... See full document

... Stem cells are the unspecialized cells that have the capability of giving rise to specialized ...all cells and are expected one day to cure a wide range of ...Embryonic stem ... See full document

... mesenchymal stem cells ’ is not just a matter of ...mesenchymal stem cells ’ (MSCs), currently used to denote cultures of fibroblastic cells from virtually every tissue or organ (da ... See full document

... hematopoietic stem cells), CD73, CD90, and CD105 (a marker of mesen- chymal stem cells, MSCs), which may represent the tar- geting ability of cell tissue products, have been analyzed and have ... See full document