[PDF] Top 20 Sleep apnoea and metabolic dysfunction

... Increased neck circumference is another marker of visceral adiposity frequently associated with OSA. Several studies have recently assessed its independent contribution to prediction of OSA severity, with variable ... See full document

... and sleep education) for 12 weeks, followed by assessment of 24-h mean arterial blood pressure and cardiovascular ...cardio-metabolic dysfunction [17, ... See full document

... As summarised here, a fast growing body of studies using experimental models has provided substantial support of the key role of IH-induced adipose tissue inflammation in metabolic dysfunction in rodents. ... See full document

... obesity, metabolic syndrome, hyperten- sion, type 2 diabetes, ...arterial dysfunction in OSA patients with car- diometabolic risk factors, independent from weight loss and risk factor ... See full document

... Obstructive sleep apnoea (OSA) syndrome affects about 13% of the male and 7–9% of the female ...and metabolic consequences, including coronary artery ...during sleep, systemic effects and ... See full document

... during sleep is similarly regulated in healthy males and females [78, ...during sleep was lower in the luteal compared to the follicular phase, in agreement with a “ protective ” effect of progesterone ... See full document

... following SDB. Guarnieri et al 92 found SDB to be more severe among patients with vascular dementia while no increased prevalence of the same was found in other dementia syndromes. Shin and colleagues found ... See full document

... Over the past few years, there has been accumulating evidence of a causal relationship between OSA and the development of atherosclerosis and associated diseases. This has been supported by numerous studies demonstrating ... See full document

... reproductive metabolic disorder affecting nearly 20% females, ...axis dysfunction and impaired ovarian steroidogenesis further influence the ...chronic metabolic consequences: cardiovascular disease ... See full document

... in sleep apnoea patients should be interpreted with great caution in view of several methodological ...investigated sleep laboratory populations that did not represent the general population, or the ... See full document

... complications of sleep disorders. However, in 66 (lean) Chinese patients with OSAS compared with 20 BMI-matched controls, the adiponectin levels were lower in the OSAS group [61], although the adiponectin serum ... See full document

... vascular dysfunction, with special attention to circadian rhythms and the role of nuclear ...while sleep appears as a generally protective ...that sleep disorders may affect the cardiovascular system ... See full document

... OF SLEEP APNOEA SYNDROME Measures to reduce the impact of sleep apnoea and the related driver sleepiness on road traffic accidents have little meaning if there are inadequate facilities ... See full document

... between sleep apnoea and sleepi- ...by sleep apnoea have an AHI of less than ...between sleep apnoea and sleepiness as this is now ...of sleep disordered breathing has ... See full document

... sleep apnoea. Of all the several predisposing factors to obstructive sleep apnoea, Mallampati, neck circumference and BMI have been shown to contribute more when compared to others ... See full document

... severe sleep apnoea are shown in table 2 and online supplementary e- Table ...have sleep- related ...with sleep- related hypoxaemia had a mean SpO 2 of ... See full document

... used apnoea-screening questions but it is important to notice that negative answers to these questions or absence of the typical OSA features does not eliminate the possibility of ...proper sleep assessment ... See full document

... Conclusion Swimmers and non- swimming athletes suffer significantly more with excessive daytime sleepiness than healthy controls. In elite swimmers, this is likely linked to high prevalence of OSA. PSQI scores do not ... See full document

... Obstructive sleep apnoea (OSA) is characterised by at least five 10-s episodes of apnoea or markedly shallow breathing per 1 h of sleep, which can lead to severe, sometimes life-threatening ... See full document

... Despite the strong evidence of increased MVA risk in OSAS patients, reports differ regarding the contribution of disease severity based on the apnoea – hypopnoea index (AHI) or the degree of daytime sleepiness ... See full document