[PDF] Top 20 Stem cells and transgenic mice in the study of development
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Stem cells and transgenic mice in the study of development
... Int J Dn BinI 37 89 99 (1993) 89 SPecial Review Stem cells and transgenic mice in the study of development' RALPH L BRINSTER* School of Veterinary Medicine, University of Pennsylvania Philadelphia, US[.] ... See full document
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Expression of the Ly-6e.1 (Sca-1) gene in transgenic mice for the study of haematopoietic stem cells during development
... Hmyc transgenic mice is evident in the ...Ly>6E.l/w^c transgenic liver in LM7 and LM8 mice as compared with non-transgenic littermates, despite the overtly normal gross appearance of ... See full document
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Distributed Features of Vimentin-Containing Neural Precursor Cells in Olfactory Bulb of SOD1G93A Transgenic Mice: a Study about Resource of Endogenous Neural Stem Cells
... precursor cells (NPCs) to repairing the degenerative motor neurons in ALS, we studied the alteration of endogenous vimentin-containing NPCs in olfactory bulb (OB) at the different stages of SOD1 wlid-type and G93A ... See full document
10
Embryonic stem cells and transgenic mice in the study of hematopoiesis
... hematopoietic cells were identified through the directed search for DNA-binding pro- teins that mediate cell-specific gene ...The study of such factors in the context of development is predicated on ... See full document
8
Transgenic mice the early days
... that transgenic methodology could be used to explore many different experimental questions and we could not resist the opportunities to collaborate with specialists throughout the country on these various ...cell ... See full document
8
An efficient strategy for generation of transgenic mice by lentiviral transduction of male germline stem cells in vivo
... present study. Lentiviral particles with spermatogon- ial stem cell (SSC) specific promoter would infect SSC solely in testis and probably lead to transgenic spermato- zoa more efficiently, ... See full document
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Transgenic expression of tpr met oncogene leads to development of mammary hyperplasia and tumors
... transfected cells and tumor formation in heter- ogeneic immune competent mice ...allows cells to escape immune sur- ...our transgenic mice through a mechanism independent of mitogenic ... See full document
7
Stem cell factor and granulocyte colony-stimulating factor reduce β-amyloid deposits in the brains of APP/PS1 transgenic mice
... marrow stem cells and homing of bone marrow-derived cells in the brain are enhanced by SCF+G-CSF in AD ...hematopoietic stem cells ...mononuclear cells express CD117 antigen ... See full document
8
Epstein-Barr Virus LMP2A Interferes with Global Transcription Factor Regulation When Expressed during B-Lymphocyte Development
... B-cell development, before expression of a func- tional BCR, LMP2A may have a similar inhibitory effect on signaling from the ...our transgenic mouse model, LMP2A expression is driven by the Ig heavy-chain ... See full document
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Role of autophagy in the maintenance and function of cancer stem cells
... first study, the authors showed that a CD133 antibody inhibited spheroids and xenograft tumor forma- tion in NOD/SCID mice, and induced cancer cell death by sup- pressing autophagy and promoting necrotic ... See full document
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Influence of mesenchymal stem cells on metastasis development in mice in vivo
... Mononuclear cells were separated by centrifugation over a Histopaque gradient (Sigma-Aldrich, ...adherent cells were removed by washing with phosphate- buffered saline (PBS), and monolayers of adherent ... See full document
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Defining the cell lineages of the islets of Langerhans using transgenic mice
... their development and differentiation for up to 12 days (Sanvito et ...the development of acinar tissue without decreasing the amount of ducts, mesenchyme, and endocrine ...the development of the ... See full document
7
Defining a role for the homeoprotein Six1 in EMT and mammary tumorigenesis
... that transgenic mice that express the homeoprotein Six1 in mammary epithelial cells show increases in stem/progenitor cell populations and subsequent tumor development, while in a ... See full document
5
Of birds and mice: hematopoietic stem cell development
... endothelial cells and reversibly, endothelial markers are often expressed by primitive hematopoietic ...vessel development (Garcia-Porrero et ...few cells of the clusters express this marker (Manaia ... See full document
7
goosecoid expression represses Brachyury in embryonic stem cells and affects craniofacial development in chimeric mice
... Conserved sequence elements between the mouse and frog Brachyury promoter contain potential binding sites for two other transcription factors that are important regulators of early vertebrate development. LEF-1 ... See full document
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Stem cells for the replacement of inner ear neurons and hair cells
... ear stem cells grew processes that contacted hair cells in an explant of the organ of Corti that had been denervated by β -bungarotoxin (Martinez-Monedero et ...hair cells, but we found that ... See full document
8
On the origin of amniotic stem cells: of mice and men
... extensive study in rhesus monkey has established cavita- tion as the process of amniogenesis (Enders et ...of cells. Soon after implantation (6 dpf), the epiblast cells start to polarize and ... See full document
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Dysregulated hematopoiesis and a progressive neurological disorder induced by expression of an activated form of the human common beta chain in transgenic mice
... ony-forming cells (CFU-GM and CFU-M) in the absence of added ...All transgenic mice display a myeloprolif- erative disorder characterized by splenomegaly, erythrocy- tosis, and granulocytic and ... See full document
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Migration of lymphatic endothelial cells and lymphatic vascular development in the craniofacial region of embryonic mice
... Lymphatic development in mice is initiated in the trunk at embryonic day (E) ...This study aimed to examine the origin of craniofacial lymphatic endothelial cells (LECs) and the developmental ... See full document
10
Accelerated hepatocellular carcinoma development in CUL4B transgenic mice
... CUL4B transgenic and littermate control male mice were injected with DEN (10 mg/Kg) at postnatal day 14, and were administered with PB in the drinking water ...CUL4B transgenic mice and ... See full document
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