[PDF] Top 20 Non structural protein 1 is required for West Nile virus replication complex formation and viral RNA synthesis
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Non structural protein 1 is required for West Nile virus replication complex formation and viral RNA synthesis
... a non-structural glycoprotein that is expressed on the plasma membrane of infected cells and secreted into the extracellular ...and viral replication occurs on the cytosolic face of the ER, ... See full document
14
Stimulation of poliovirus RNA synthesis and virus maturation in a HeLa cell free in vitro translation RNA replication system by viral protein 3CDpro
... Picornaviridae virus fam- ily, replicates its plus strand genomic RNA within replica- tion complexes contained in the cytoplasm of the infected ...the viral and cellular proteins needed for ... See full document
19
West Nile Virus-Induced Activation of Mammalian Target of Rapamycin Complex 1 Supports Viral Growth and Viral Protein Expression
... RNA virus infections, much less is known about how mTOR function impacts viral ...C virus (HCV) nonstructural protein 5A was shown to activate mTOR inde- pendent of PI3K and Akt ... See full document
14
Exclusion of West Nile Virus Superinfection through RNA Replication
... in viral nonstructural genes selectively enhanced viral replication in NeoRep BHK-21 cells; the V9M mutation in 2K peptide exhibited a greater enhancement than that of the K24R mutation in NS4a ...by ... See full document
12
Identification of cis-Acting Nucleotides and a Structural Feature in West Nile Virus 3′-Terminus RNA That Facilitate Viral Minus Strand RNA Synthesis
... cell protein eEF1A on the WNV 3=-terminal SL RNA ...of viral minus strand RNA synthesis ...strand viral RNA reduced the amount of progeny genome produced, indicating that ... See full document
15
The Human Immunodeficiency Virus Type 1 TAR RNA Upper Stem-Loop Plays Distinct Roles in Reverse Transcription and RNA Packaging
... immunodeficiency virus type 1 (HIV-1) RNA genome is flanked by a repeated sequence (R) that is required for HIV-1 ...activator protein, Tat, to promote high levels of gene ... See full document
8
Formation of the Poliovirus Replication Complex Requires Coupled Viral Translation, Vesicle Production, and Viral RNA Synthesis
... by protein 2BC and, con- sequently, carrying only this viral protein were shown not to contribute to viral replication complexes formed after subse- quent virus ...of ... See full document
11
The Capsid-Binding Nucleolar Helicase DDX56 Is Important for Infectivity of West Nile Virus
... decreased synthesis of viral RNA or proteins, infected cell lysates were subjected to quantitative RT-PCR (qRT-PCR) and immunoblot analyses, ...of viral genomic RNA ...WNV ... See full document
10
Inhibition of Pattern-Recognition Receptor Signaling by the Secreted Form of West Nile Virus Non-structural Protein 1.
... type 1 interferon production as well as the production of proinflammatory ...of virus infection are a class of PRRs called Toll-like receptors ...recognize virus replication intermediates, ... See full document
145
Interaction between the Cellular Protein eEF1A and the 3′-Terminal Stem-Loop of West Nile Virus Genomic RNA Facilitates Viral Minus-Strand RNA Synthesis
... clone RNA had a negative effect on viral growth suggested that this viral RNA- cell protein interaction occurred in infected ...various viral nonstructural proteins or dsRNA ... See full document
16
A 48-amino-acid region of influenza A virus PB1 protein is sufficient for complex formation with PA.
... polymerase complex, being responsible for RNA chain ...A virus PB1 expressed in the absence of other viral products accumulates in the nucleus of the ...all RNA-dependent RNA ... See full document
8
Annexin A2 Is Involved in the Formation of Hepatitis C Virus Replication Complex on the Lipid Raft
... scaffold protein Anxa2, which assists in the organization of membrane microdomains (14, 16, 17, 20, 21, 25, ...scaffold protein to help build the HCV ...HCV RNA replication in HCVrep-HA SGR ... See full document
12
Investigating the foot and mouth disease virus 3A protein
... allow RNA synthesis the vRNA is thought to ...PCBP2 complex at the 5’UTR with PABP that is bound to the poly A tail (Herold and Andino, ...in viral RNA replication is the ... See full document
230
AUF1 p45 Promotes West Nile Virus Replication by an RNA Chaperone Activity That Supports Cyclization of the Viral Genome
... genomic RNA to be single ...initiate RNA synthesis (Fig. 1) (10, 20–22). FIG 1 Genomic organization of WNV RNA; structural organization of the RNA’s 5= and 3= ...Conserved ... See full document
14
CNOT4 Mediated Ubiquitination of Influenza A Virus Nucleoprotein Promotes Viral RNA Replication
... the RNA and those not in contact. In the structural model of the viral helical RNP complex, modified from that reported by Arranz et ...the RNA-binding groove of NP ...binds viral ... See full document
16
Functional Consequences of RNA 5′-Terminal Deletions on Coxsackievirus B3 RNA Replication and Ribonucleoprotein Complex Formation
... no replication was detected following transfection of a CVB3 genome with a 32-nucleotide deletion of the 5= NCR into HeLa cells ...of replication of TD RNAs in HeLa S10 cell in vitro RNA ... See full document
17
Evidence for DNA Hairpin Recognition by Zta at the Epstein-Barr Virus Origin of Lytic Replication
... herpesvirus replication has become increasingly important over the past few decades as the inci- dence of human immunosuppression has ...Epstein-Barr virus (EBV), is the etiological agent underlying ... See full document
10
Africans, Cherokees, and the ABCFM Missionaries in the Nineteenth Century: An Unusual Story of Redemption
... E protein independently of its role as an internal signal sequence in the ...the viral envelope proteins prM and E from a separate IRES-dependent cistron located in the viral 3' ...new viral ... See full document
142
The Effects of P320Sc Mutation in West Nile Non-structural Protein 1 (NS1) and the Generation of Aptamers to Detect Dengue NS1 in the Context of Infection.
... Additionally, our method of negative selection was modified from typical negative selection procedures. Published protocols describing negative selection describe immobilizing irrelevant proteins onto beads using ... See full document
159
Neuronal Survival Following Rna Virus Infection Facilitates Viral Persistence, Reactivation, And Pathogenesis
... a viral trigger, but the inability to consistently detect viral antigens or recover infectious virus from host tissue has cast doubt on such ...detect viral components, in the case of MS, a ... See full document
156
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