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[PDF] Top 20 Studies on the role of histones in the structure and function of chromatin

Has 10000 "Studies on the role of histones in the structure and function of chromatin" found on our website. Below are the top 20 most common "Studies on the role of histones in the structure and function of chromatin".

Studies on the role of histones in the structure and function of chromatin

Studies on the role of histones in the structure and function of chromatin

... In the preparation of chromatin samples for template activity studies we have, therefore, routinely extracted the original purified sheared chromatin three times with 0.15 M NaC1 - 0.[r] ... See full document

170

Methionine Adenosyltransferase Structure and Function Studies: the Novel Role of a Gating Loop and a Disease-Causing Residue in Enzyme Catalysis

Methionine Adenosyltransferase Structure and Function Studies: the Novel Role of a Gating Loop and a Disease-Causing Residue in Enzyme Catalysis

... product interaction. Gln113Ala mutation results in about 25 % decrease in SAMe production compared to the wild type, while SAMe formation of Pro115Gly is normal. Although Gln113 directly interacts with the oxygen atom of ... See full document

190

The central role of chromatin in autoimmune responses to histones and DNA in systemic lupus erythematosus

The central role of chromatin in autoimmune responses to histones and DNA in systemic lupus erythematosus

... with chromatin removed 85-100% of reactivity to (H2A-H2B)-DNA, (H3-H4)2- DNA, and native ...on chromatin, with some epitopes requiring quaternary protein-DNA ...with chromatin being a potent ... See full document

10

A Role for the Nucleoporin Nup170p in Chromatin Structure and Gene Silencing

A Role for the Nucleoporin Nup170p in Chromatin Structure and Gene Silencing

... silenced chromatin. By contrast, studies in yeast and metazoan cells have established functional links between specific Nups and transcriptionally active ...and chromatin domains that generally ... See full document

15

Linker histones are fine scale chromatin architects modulating developmental decisions in Arabidopsis

Linker histones are fine scale chromatin architects modulating developmental decisions in Arabidopsis

... fundamental role in chromatin accessibility, very little was known about the specific impact of H1 at the structural, epigenetic, and gene expression level in ...H1 function on nucleosome occupancy ... See full document

22

Structure Function Studies Of Hiv-1 Protease

Structure Function Studies Of Hiv-1 Protease

... While changing the binding pocket may increase hydrogen bond formation, this also alters the conformation of the inhibitor. 5.3 Discussion Three multi-drug resistant HIV-1 protease clinical isolates were selected from ... See full document

65

Structure-Function Studies On Novel Signaling Regulators

Structure-Function Studies On Novel Signaling Regulators

... bond is 1.8 Å, and those bonds in the intermediate II were in great agreement with that (Fig. 3.4D). The cyclic intermediate II was stabilized by extensive hydrogen bonds from both the backbone and the side-chains as ... See full document

195

The role of heterogeneity in asthma: a structure-to-function perspective

The role of heterogeneity in asthma: a structure-to-function perspective

... inclusive of their branching angles obtained from previ- ous morphometric studies with human airways [68, 85]. A stack-based algorithm traverses the airway tree and determines the highest branch to designate for ... See full document

11

Chromatin remodelers: from function to dysfunction

Chromatin remodelers: from function to dysfunction

... Abstract: Chromatin remodelers are key players in the regulation of chromatin accessibility and nucleosome positioning on the eukaryotic DNA, thereby essential for all DNA dependent biological ...and ... See full document

26

Insights from structure-function studies of variant fibrinogen

Insights from structure-function studies of variant fibrinogen

... venom enzymes like batroxobin and reptilase (15). Thus, there is controversy surrounding the role of “B:b” interactions in fibrin polymerization. 1.4 Recombinant Fibrinogen Because plasma fibrinogen binds proteins ... See full document

128

In the loop: how chromatin topology links genome structure to function in mechanisms underlying learning and memory

In the loop: how chromatin topology links genome structure to function in mechanisms underlying learning and memory

... Physiological neuronal activity induces DNA double-strand breaks Recently, several groups have described a perplexing phenomenon that occurs in response to neuronal activity: the formation of DNA double-strand breaks ... See full document

16

Chromatin, DNA structure and alternative splicing

Chromatin, DNA structure and alternative splicing

... of chromatin remodelers. But what happens with the histones and how do nucleosomes re-assemble when RNAPII transcribes a region? It has been proposed that DNA forms a loop that allows DNA behind RNAPII to ... See full document

9

The role of extracellular histones in critical illness and their application in acute pancreatitis

The role of extracellular histones in critical illness and their application in acute pancreatitis

... nuclear chromatin is cleaved into nucleosomes, which are released extracellularly 232 and further degraded into individual ...Recent studies demonstrate their direct toxicity to endothelial cells as well as ... See full document

186

Structure-function studies of the vaccinia virus complement control protein.

Structure-function studies of the vaccinia virus complement control protein.

... its role in modulating the host immune response. In previous studies, the ability of VCP to bind heparin was found to permit uptake by mast cells – possibly allowing for tissue persistence over an extended ... See full document

299

Dynamic Nuclear Architecture and Chromatin Function (EuroDYNA)

Dynamic Nuclear Architecture and Chromatin Function (EuroDYNA)

... as histones) during DNA replication. Both the acetylation of histones and its timely removal are important for efficient DNA repair and cell survival in response to DNA ...a role in higher eukaryotes ... See full document

16

Role of growth hormone and chromatin structure in regulation of sex differences in mouse liver gene expression

Role of growth hormone and chromatin structure in regulation of sex differences in mouse liver gene expression

... Other studies have reported that Mef2a, Mef2c and Mef2d RNA and protein are present in hepatic stellate cells, which comprise 5-8% of resident liver cells and are activated in a Mef2-dependent manner to a ... See full document

350

Methods for analyzing the role of DNA methylation and chromatin structure in regulating T lymphocyte gene expression

Methods for analyzing the role of DNA methylation and chromatin structure in regulating T lymphocyte gene expression

... of chromatin structure in the region, provides information regarding both the presence and functional significance of the methylation ...the chromatin structure around the same genes in ... See full document

15

The conserved role of sirtuins in chromatin regulation

The conserved role of sirtuins in chromatin regulation

... Throughout chromatin evolution, Sirtuins have maintained an intimate functional relationship in regulating its structure and function via their targeting of histones, particularly H4K16Ac, as ... See full document

21

Role of C-type natriuretic peptide in cardiac structure and function

Role of C-type natriuretic peptide in cardiac structure and function

... addition, studies of the lineage of natriuretic peptide genes have suggested that ANP and BNP originated from CNP via gene duplication (Inoue et ...association studies (GWAS) have established a relationship ... See full document

248

Studies on Plant and Animal Histones

Studies on Plant and Animal Histones

... the salt solution -- sucrose solution interface where they would be un- available for subsequent recovery (Cruft~ al., 1958). Lysine-rich histones are not aggregated [r] ... See full document

214

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