[PDF] Top 20 Sumo and the cellular stress response
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Sumo and the cellular stress response
... the response to nutrient starvation is rewiring of gene expression ...the cellular response to nutrient status ...many cellular pro- cesses, including rewiring of transcriptional programs [87, ... See full document
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Cellular stress response, sirtuins and UCP proteins in Alzheimer disease: role of vitagenes
... Consistently to the observed changes in AD lymphocytes, analysis of plasma in AD patients showed higher expres- sion levels of Sirt-1 (Figure 5). Expression levels of Sirt-2 were also measured and results, reported in ... See full document
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Differential p38-dependent signalling in response to cellular stress and mitogenic stimulation in fibroblasts
... proliferation Cellular stress is known to induce p38-dependent cell cycle arrest in NIH3T3 cells as does constitutive activation of p38 as mentioned above ...in response to anisomycin, a well- known ... See full document
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Functional genomics and proteomics of the cellular osmotic stress response in `non model' organisms
... for model species, and currently projects are underway to generate specific antibodies for every human and every mouse protein. Therefore, this approach is less work-intensive for model species. We have used two ... See full document
10
Molecular Effects of the Nampt Inhibitor FK866 on Leukemia Cells
... Understanding cellular mechanisms of response to FK866 can help the development of new analogues that exhibit less toxicity and more ...early cellular response to FK866- induced metabolic ... See full document
124
S nitrosylation of the thioredoxin like domains of protein disulphide isomerase and its role in neurodegenerative conditions
... network response, involv- ing the upregulation of several molecular chaperones that pre- vent protein aggregation, termed the unfolded protein response (UPR), followed by ER-associated degradation (ERAD), ... See full document
8
SUMO Binding by the Epstein-Barr Virus Protein Kinase BGLF4 Is Crucial for BGLF4 Function
... 11 SUMO binding proteins identified was the conserved protein kinase ...potential SUMO interaction motifs (SIMs) in BGLF4 identified N- and C-terminal ...dinated SUMO binding by the N- and C-terminal ... See full document
10
Targeting the SUMO pathway for neuroprotection in brain ischaemia
... individual SUMO targets involved in brain ischaemia is just begin- ...the response to brain ischaemia is largely ...vivo SUMO targets regulated by ...prominent SUMO target induced by ...in ... See full document
7
eIF2B bodies and their role in the integrated stress response
... of cellular stress was used as a tool to manipulate eIF2B activity and the movement of eIF2 was ...diverse cellular stresses results in the phosphorylation of eIF2α at serine ...under stress ... See full document
206
Changes in expression of selected cellular stress response genes after passive body overheating in sauna and moderate exercise in judo athletes and untrained people
... the cellular level, such as the expression of stress-related ...cal stress, changes in temperature, or oxidative stress ...the cellular response to stress is indepen- dent ... See full document
8
Original Article Expression and function of protein phosphatase 5 in hepatocellular carcinoma
... in response to hormones or cellular stress, and elevated levels of this protein may be associated with development of some types of cancers by reversible phosphorylation at serine and threonine ... See full document
9
Heat shock proteins and hormesis in the diagnosis and treatment of neurodegenerative diseases
... the stress response. Exercise stress has been reported to induce the release of HSP70 from the human brain into the blood stream in ...addition, stress proteins, such as HSP90 are necessary ... See full document
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Temperature tolerance of different larval stages of the spider crab Hyas araneus exposed to elevated seawater PCO2
... for cellular stress phenomena including the heat shock response as a protection process, for acid– base regulation as an important energy consuming process [21] and for mitochondrial energy ... See full document
22
DNA damage and cell cycle events implicate cerebellar dentate nucleus neurons as targets of Alzheimer's disease
... In addition to ectopic cell cycling, AD is also linked to DNA damage. Accumulation of DNA damage in neurons is associated with aging [27] and is exacerbated in neuro- degenerative disorders including AD [28,29]. The ... See full document
11
Molecular basis of cardiac performance Plasticity of the myocardium generated through protein isoform switches
... Thus, similar to the mitogenic response of a variety of cell types, induction of the cellular protooncogenes and major stress protein genes reflect early changes occurring in the nuclei [r] ... See full document
9
Cellular stress response mechanisms of Rhizoma coptidis: a systematic review
... and cellular differentiation mediated Raf/MEK1/ERK1/2, and then down regulating the main transcription factors of adipose formation, such as PPAR-c, C/EBP-α, SREBP-1c, and FAS in 3T3-L1 adipocytes ... See full document
14
Reovirus Induces and Benefits from an Integrated Cellular Stress Response
... The extent of IFN-  mRNA induced as a consequence of reovirus infection correlates with ISG expression and is asso- ciated with apoptosis induction. As predicted, this compara- tive analysis revealed that a number of ... See full document
15
Cellular and humoral responses following minimally invasive surgery : role of reactive oxygen species
... environmental elements controlling tumour transformation, development and associated vascularisation are currently the focus of therapeutic development. Apoptosis of human lung epithelial cancer H460 cells, inhibited by ... See full document
22
Roles of Long non coding RNAs in Cellular Stress Response
... oxidative stress and in the transcription dysregulation observed in neurodegeneration (Goenka et ...oxidative stress and that these transcripts are expressed in the degenerating neurons of patients with ... See full document
8
Cellular eIF2B subunit localisation: implications for the integrated stress response and its control by small molecule drugs
... For subsequent rounds of translation initiation to occur, eIF2-GTP must be replenished within the cell. eIF2-guanosine diphosphate (GDP) is released from the PIC in complex with eIF5, which functions as a GDP ... See full document
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