[PDF] Top 20 SYNTHESIS AND ANTICANCER EVALUATION OF SOME NOVEL FUSED PYRAZOLOPYRIMIDINE DERIVATIVES.
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SYNTHESIS AND ANTICANCER EVALUATION OF SOME NOVEL FUSED PYRAZOLOPYRIMIDINE DERIVATIVES.
... Four compounds were selected by the National Cancer Institute (NCI, Bethesda, USA) at one dose (10 -5 M) in the full 60 human cancer cell lines orderly into subpanels derived from nine various human cancer forms: ... See full document
6
Synthesis and anticancer evaluation of some fused pyrazolopyrimidines and their S acyclic nucleosides
... of some S-acyclic nucleosides of pyrazolo[3,4-d]pyrimidines ...the synthesis and structure characterization of pyrazolo[3,4- d][1,3]thiazolidino[3,2-a]pyrimidine 10 and ... See full document
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Synthesis and anticancer screening of some novel substituted pyrazole derivatives
... Novel derivatives of substituted pyrazole ring incorporated to or fused with other heterocyclic ring systems were ...hydrazine derivatives to afford the pyrazolo[3,4-c]pyrazol ... See full document
9
A NOVEL SYNTHESIS OF FUSED PYRAZOLOPYRIMIDINE: PYRAZOLO-TRIAZOLO-PYRIMIDINE FOR ANTICANCER EVALUTION.
... The fused mass thus obtained was treated with ethanol, collected by filtration and washed by ethanol, methanol, ethyl acetate, acetone and hexane to afford compound 4 and 5, ... See full document
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Synthesis, characterization and evaluation of anticancer activity of some novel 4 thiazolidinone derivatives
... These synthesis compounds were evaluated for their in vitro anticancer activity using MTT assay. A preliminary screening against both Human Acute Monocytic Leukemia - HL- 60 cell lines and Human Breast ... See full document
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BENZOTRIAZOLE - OXADIAZOLE HYBRIDS AS MEDICINAL AGENTS THE SIGNIFICANCE IN UNITY IS AN ETERNAL WONDER
... HL. Synthesis, biological evaluation, and molecular docking studies of novel 1, 3, 4-oxadiazole derivatives possessing benzotriazole moiety as FAK inhibitors with anticancer ... See full document
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Synthesis and evaluation of some pyrazoline derivatives as anticancer agents
... Breast cancer is expected to account for 203 500 new cancer cases and 39 600 deaths in 2002. Although major advances have been made in early detection, prevention, and treatment, the need for more effective therapy in ... See full document
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Synthesis and Biological Evaluation of Novel Homopiperazine Derivatives as Anticancer Agents
... for novel and ef- fective ...discover novel agents that selec- tively kill tumor cells or inhibit their proliferation with- out the general toxicity, the use of traditional cancer chemotherapy is still very ... See full document
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Synthesis and Anticancer Activity of Certain Fused Pyridazine Derivatives
... phenylhydrazone derivatives, anthranilic acid derivatives, thiosemicarbazide or substituted benzoyl hydrazide to afford the corresponding derivatives 2, 3a-c, 4a-d, 5 and 6a-c ...their ... See full document
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SYNTHESIS AND EVALUATION OF NOVEL THIOSEMICARBAZONE DERIVATIVES AS ANTICANCER AGENTS
... Adamantyl derivatives is also having interesting biological properties and most promising towards anticancer ...A novel series of compounds of thiosemicarbazones were prepared by conjugating ... See full document
13
Design, synthesis and biological evaluation of some novel Schiff base derivatives as potential anticancer agents
... Identification of molecular targets involved in proliferation, malignancy and cell death were helpful in the rational based design of new anticancer agents. Protein kinases are one of these targets which play an ... See full document
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Synthesis, Characterization and Antibacterial Activities of Novel Thieno, Pyrazol Pyridines and Pyrazolopyrimidine Derivatives
... [24], anticancer activities [25-27], acytotoxic agent against atumorigenic cell line (potent anti-tumor) [28], Thienopyridines are used as an anti-tumor in three representative human tumor cell lines ... See full document
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A NOVEL FUSED PYRIDOPYRIMIDINE DERIVATIVES: SYNTHESIS AND CHARACTERIZATION
... Pyridopyrimidine derivatives are a privileged bicyclic ring ...importance; synthesis of these compounds is considerable interest. Fused pyridopyrimidine derivatives if present in compounds ... See full document
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Synthesis, characterization and evaluation of antitubercular and analgesic activity of some novel pyrazolopyrimidine and pyrazolopyridine derivatives
... 665 www derpharmachemica comt Available online a Scholars Research Library Der Pharma Chemica, 2014, 6(2) 75 82 (http //derpharmachemica com/archive html) ISSN 0975 413X CODEN (USA) PCHHAX 75 www scho[.] ... See full document
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SYNTHESIS AND BIOLOGICAL ACTIVITY EVALUATION OF SOME FUSED IMINO PYRIMIDO BENZOTHIAZOLE DERIVATIVES
... system, synthesis of such condensed system has attracted much attention in recent ...a novel synthesis and biological activity evaluation of 9-chloro-10-fluoro-15- ... See full document
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SYNTHESIS AND STUDIES ON SOME NOVEL DERIVATIVES OF A FUSED HETEROCYCLIC SYSTEM
... ring fused to the β-lactam one. Recently, some other types of biological activity besides the antibacterial activity have been reported in compounds containing azetidines-2-one ...[13], anticancer ... See full document
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Synthesis of some novel heterocyclic azo dyes for acridine derivatives and evaluation of their antibacterial activities
... comparative evaluation of active compounds will required further studies, the data reported in this article may be helpful guide for the medicinal chemist who are working in this ... See full document
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COUMARIN AS A VERSATILE SYNTHON IN MEDICINAL CHEMISTRY
... Naik et al (2018) synthesized coumarin linked with pyrimidine derivatives via microwave irradiation. 3-acetyl coumarin was synthesized from salicylic aldehyde and acetyl acetic ester in presence of ethanol and few ... See full document
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Synthesis and biological activity evaluation of some fused pyrimido benzothiazole derivatives
... The screening of antimicrobial activity of newly synthesized compound 9-chloro-3-cyano 8-fluoro-2 methylthio-4- oxo- 4H-Pyrimido [2, 1-b] [1,3] benzothiazole (3) and its derivatives (4a-6d) has been carriedout ... See full document
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Insilico design, synthesis, characterization and biological evaluation of some novel 1 hydroxynapthelene 2 yl derivatives
... and synthesis, characterization and to investigation of anti- inflammatory activity in ...vivo. Novel Chalcones are prepared from 2-acetyl-1-naphthol and substituted aromatic ... See full document
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