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[PDF] Top 20 Systematic analysis of protein interaction network associated with azoospermia

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Systematic analysis of protein interaction network associated with azoospermia

Systematic analysis of protein interaction network associated with azoospermia

... Non-obstructive azoospermia is a severe infertility ...genes associated with azoospermia and to map their relationship, we present the first protein-protein interaction ... See full document

10

Original Article Protein-protein interaction (PPI) network and significant gene analysis of breast cancer

Original Article Protein-protein interaction (PPI) network and significant gene analysis of breast cancer

... The abnormal expression genes which were related with extracellular matrix interaction function indicated the universality of risk of cancer metastasis in breast cancer. The abnor- mal expression of chemokine ... See full document

12

Original Article Data-independent acquisition strategy for the serum proteomics of tuberculosis

Original Article Data-independent acquisition strategy for the serum proteomics of tuberculosis

... proteomic analysis can usually detect th- ousands of proteins and reveal hundreds of dysregulated proteins, and the systematic and comprehensive data analysis is important for fully extracting ... See full document

14

RETRACTED ARTICLE: Establishing an osteosarcoma associated protein-protein interaction network to explore the pathogenesis of osteosarcoma

RETRACTED ARTICLE: Establishing an osteosarcoma associated protein-protein interaction network to explore the pathogenesis of osteosarcoma

... enrichment analysis using the online biological classification tool DAVID, and obtained 15 significantly enriched functions (Table 1, P < ...GO analysis according to their ... See full document

7

Original Article Identification of key genes associated with idiopathic pulmonary fibrosis using bioinformatics analysis

Original Article Identification of key genes associated with idiopathic pulmonary fibrosis using bioinformatics analysis

... Tumor Associated Gene (TAG) and Tumor Suppressor Gene (TSGene) databases, the screened DEGs were further ...DEGs, protein-protein interactions (PPIs) were pre- dicted by STRING and PPI network ... See full document

9

Gene expression profiles and protein&amp;ndash;protein interaction network analysis in AIDS patients with HIV-associated encephalitis and dementia

Gene expression profiles and protein&ndash;protein interaction network analysis in AIDS patients with HIV-associated encephalitis and dementia

... enrichment analysis, it is clear that the majority of enriched GO terms of DEGs from the samples of AIDS patients were correlated with cell signaling pathways, endocytosis-mediated, and cell–cell adhesion ... See full document

12

Original Article The PPAR signaling pathway as a potential biomarker for the diagnosis of breast cancer

Original Article The PPAR signaling pathway as a potential biomarker for the diagnosis of breast cancer

... a protein-protein interaction (PPI) network were built in the training dataset (GSE42568) using the twenty-one differentially expressed genes (DEGs) which were annotated into the PPAR ... See full document

10

Identification of Key Proteins Associated with Myocardial Infarction using Bioinformatics and Systems Biology

Identification of Key Proteins Associated with Myocardial Infarction using Bioinformatics and Systems Biology

... expression analysis, 11 genes that correspond to NCBI generated annotation were found to be up-regulated (Table ...Enrichment Analysis of these 11 genes, several of their molecular mechanisms have been ... See full document

11

IN SILICO ANALYSIS OF PROTEIN-PROTEIN INTERACTION NETWORK OF HUTCHINSON GILFORD PROGERIA SYNDROME

IN SILICO ANALYSIS OF PROTEIN-PROTEIN INTERACTION NETWORK OF HUTCHINSON GILFORD PROGERIA SYNDROME

... lamina. Analysis of protein interaction network in the cell would be the key to understand how complex processes, lead to ...diseases. Protein-protein interaction ... See full document

12

RETRACTED ARTICLE: Analysis of protein-protein interaction network and functional modules on primary osteoporosis

RETRACTED ARTICLE: Analysis of protein-protein interaction network and functional modules on primary osteoporosis

... signaling protein in the RLRs pathway [28], and RLRs are a family of DExD/H box RNA helicases which function as cytoplasmic sensors of pathogen-associated molecular patterns within viral RNA ...are ... See full document

9

Construction and analysis of protein-protein interaction network associated with human sperm-egg interaction

Construction and analysis of protein-protein interaction network associated with human sperm-egg interaction

... Male factor problems, mainly defined by abnormal semen analysis, are the single most conventionally diagnosed reason of infertility. In vitro fertilization (IVF) is implemented for men with no sperm dysfunction. ... See full document

44

An integrated analysis for long noncoding RNAs and microRNAs with the mediated competing endogenous RNA network in papillary renal cell carcinoma

An integrated analysis for long noncoding RNAs and microRNAs with the mediated competing endogenous RNA network in papillary renal cell carcinoma

... factor-binding protein 5), creB5 (caMP responsive element-binding protein 5), SP1 (specificity protein 1), KCNH2 (potassium voltage-gated channel subfamily H member 2), KRT75 (keratin 75), PNPLA3 ... See full document

14

Open source tool for prediction of genome wide protein-protein interaction network based on ortholog information

Open source tool for prediction of genome wide protein-protein interaction network based on ortholog information

... BLASTP analysis (Washington University, ...Princeton Protein Orthology Database (P-POD, [31]), but settled on the more up-to-date and more accessible OrthoMCL-DB database ([22], http:// ... See full document

6

PROTEIN INTERACTION NETWORK AND DRUG DISCOVERY

PROTEIN INTERACTION NETWORK AND DRUG DISCOVERY

... ABSTRACT: Protein conformation and dynamics are influenced by various factors, including binding of ligands, their physico-chemical properties, ...in interaction of protein ...of protein ... See full document

9

Identification of potential candidate genes for hypertensive nephropathy based on gene expression profile

Identification of potential candidate genes for hypertensive nephropathy based on gene expression profile

... the network. To reveal the biological functions of genes in the PPI network, the KEGG pathway enrichment analysis for DEGs in the PPI network was performed based on ... See full document

8

&lt;p&gt;Identification of a transcription factor-microRNA network in esophageal adenocarcinoma through bioinformatics analysis and validation through qRT-PCR&lt;/p&gt;

<p>Identification of a transcription factor-microRNA network in esophageal adenocarcinoma through bioinformatics analysis and validation through qRT-PCR</p>

... gene network was con- structed to study the potential molecular mechanisms, and we found that TP53-(miR-125b)-ID2 and JUN-(miR-30a)-IL1A might play signi fi cant roles in ...the network was constructed, ... See full document

12

Identification of key lncRNAs in colorectal cancer progression based on associated protein–protein interaction analysis

Identification of key lncRNAs in colorectal cancer progression based on associated protein–protein interaction analysis

... The molecular mechanism involved in the CRC pro- gression remained unclear. Therefore, it was critically important to investigate the biological mechanisms of CRC. In the present study, we identified the signifi- cantly ... See full document

9

A Meta-Heuristic Approach to Predict Protein-Protein Interaction Network

A Meta-Heuristic Approach to Predict Protein-Protein Interaction Network

... This paper is an approach to improve the work proposed in [12] significantly. In [12], the authors used firefly algorithm with non-dominated sorting (FANS), whereas the present version examines the scope of DEMO with ... See full document

10

Original Article Scree ning of hepatocellular carcinoma hub genes and construction of a control network

Original Article Scree ning of hepatocellular carcinoma hub genes and construction of a control network

... Pituitary tumor-transforming gene 1 (PTTG1) plays an important role in the regulation of tran- scription, mitosis, cell cycle regulation, chromo- some stability, DNA repair, and apoptosis [28]. Many studies have shown ... See full document

13

Analyses of gene expression profiles in the rat dorsal horn of the spinal cord using RNA sequencing in chronic constriction injury rats

Analyses of gene expression profiles in the rat dorsal horn of the spinal cord using RNA sequencing in chronic constriction injury rats

... Mitogen-activated protein (MAP) kinases; MF: Molecular function; MKP: MAP kinase phosphatase; MWT: Mechanical withdrawal threshold; NGF: Nerve growth factor; PPI: Protein-protein interaction; ... See full document

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