[PDF] Top 20 The Evolution of Genomic Imprinting

... Some genes known to control the em- bryonic development are not imprinted (Lru et al. To explain why there are only a few genes imprinted in mammals, we considered models th[r] ... See full document

... the evolution of genomic imprinting—holds, Thus, intralocus sexual conflict selects for genomic im- even in the absence of this assumption (see ...The Genomic imprinting is ... See full document

... of genomic imprinting is that offspring are more similar to one parent than to the other, depending on which parent’s genes are inactivated in those ...that genomic imprinting may have evolved ... See full document

... Drya, T. D., S. R. Mukai, R. Petersen, J. M. Rapaport, D. Walton Weisstein, A. E., M. W. Feldman and H. G. Spencer, 2002 Evolu- et al., 1989 Parental origin of mutations of the retinablastoma tionary genetic models of ... See full document

... the evolution of ...with genomic imprinting and X chromosome dosage compensation in female eutherian ...the evolution of imprinting mechanisms have been ...autosomal genomic ... See full document

... ABSTRACT Genomic imprinting shapes the genotype–phenotype relationship by creating an asymmetry between the influences of paternally and maternally inherited gene ...Consequently, imprinting can ... See full document

... Region N (Non-imprinting) has the A fixation stable to invasion by a, A successfully in- vades the a fixation, and the internal equilibrium does not ex- ist (in the biologically relevant[r] ... See full document

... that imprinting arose through selection for reduced risk of ovarian trophoblastic disease in ...which imprinting could ...opposite imprinting status has evolved at some growth-inhibiting loci ... See full document

... the evolution of ...X-imprinting: genomic conflict caused by polygamy and sex-specific selection. Genomic conflict can only explain small reductions in maternal X gene expression and cannot ... See full document

... of imprinting evolution under sexually antagonistic selection might help the authors elucidate the links between parental gene effects and sexual differences (section ... See full document

... Genomic imprinting is a conserved, essential process in mammalian development that regulates the expression of a small number of genes in a monoallelic, parent-or-origin-specific ...with imprinting ... See full document

... of imprinting in growth and behavioral ...for evolution of imprinting is that a parent–offspring “conflict” results in enhancers of prenatal and postnatal growth being of paternal origin, whereas ... See full document

... not evolution disproportionately favors such parameters is a separate question, of course (S pencer and M arks 1988; M arks and S pencer 1991), but the biological importance of cycling in these models is certainly ... See full document

... that imprinting was present in a common vertebrate ancestor that exhibited viviparity and had a placenta (Graves and Renfree, ...convergent evolution of imprinted genes in these distant groups (Pires and ... See full document

... permanently prevented from attaining evolutionary equilibrium— such as in the context of coevolutionary cycling—the phenotype may be sufficiently far from the optimum of either set of genes that these will be favored to ... See full document

... with genomic imprinting occur in germline cells and, like sequence changes, these modifications can be stably transmitted through several generations of cells or ... See full document

... that imprinting of UBE3A evolved subsequent to divergence of the eutherian and metatherian (marsupial) ...If genomic imprinting of UBE3A arose in the com- mon ancestor of modern eutherian mammals as ... See full document

... The imprinting phenomenon we describe has all of was subcultured once at a 1-wk interval before the parents the, now classical, features of genomic imprinting: The were discarded and each experiment ... See full document

... single genomic site, we combined two successive deletion fragments side-by-side and employed a transgene co-placement strategy [19] (Additional file 1: ...thymus genomic DNA demon- strated that all but two ... See full document

... and evolution were driven by ...the evolution of ST36, where multiple genomic deletions may lead to decreases in the growth rate of modern lineages of this clone, reducing the mutation rate because ... See full document