[PDF] Top 20 The stepped wedge trial design: a systematic review

... and trial protocols using the following phrases: step wedge, stepped wedge, experimentally staged introduction and the nine possible combinations of incremental/phased/ staggered and ...a ... See full document

... the trial should be incor- porated at multiple timepoints ...the stepped wedge design com- pared to the classical trial design because of the limited number of patients within ... See full document

... the trial design can put studies at risk of not delivering on their objectives [5, ...the trial to be ...the trial may have reper- cussions that ultimately result in the trial being ... See full document

... In addition to nutritional dif fi culties, patients with HNC also exhibit relatively high rates of mental health pro- blems, particularly depression. 11 Our recent study found that baseline depression predicted those ... See full document

... Cochrane review by Bricker et ...our trial is its large sample ...current trial is adequately powered to exam- ine whether third trimester ultrasound screening can reduce severe adverse perinatal ... See full document

... two systematic reviews [5, 23] and consideration of the wider literature by an Organising Committee within a theoretical framework called the Behaviour Change Wheel ... See full document

... populations. 23,27 PI CME is a learning format consisting of longitudinal practice improvement, for which physicians may earn continuing medical education credit. Participation requirements for PI CME align with ... See full document

... Methods/design: We will conduct a cluster randomised controlled stepped wedge trial, with eight clusters of 10 general practitioners each. The physicians will suggest to all of their ... See full document

... a stepped-wedge, cluster randomized controlled, clinical trial in 15 emergency departments in France recruiting all patients aged 75 years and older with a diagnosis of ...the trial, all ... See full document

... a stepped wedge, cluster randomised trial the 10 participating hospitals will be randomised to the timing of the change from the less tight to the tighter glycaemic target ... See full document

... A within-trial cost-effectiveness analysis will estimate and compare the costs and impact of ‘review and revise’ compared to standard care. The primary analysis will take an NHS perspective based on data ... See full document

... the stepped-wedge design may increases the power of the study, since health facilities acted as their own control [22], and the study allowed us to assess the intervention in realistic ... See full document

... and systematic reviews have evalu- ated the safety, efficacy and acceptability of immediate postpartum insertion of IUDs (within 10 min of delivery of the placenta) compared to delayed postpartum insertion (more ... See full document

... We review recent SWTs to identify the most commonly conducted designs and illustrate each with a case ...key design choices in planning an SWT: the randomisation method, the number of steps and length of ... See full document

... The MaxART study aims to quantify empirically the causal impacts of EAAA on a range of important economic outcomes, including healthcare expenditure, resources use, and patients’ welfare. In addition, the ... See full document

... Although 20% of the English population (approximately 10 million people) live in non-urban locations [4], rural populations are generally understudied [17,18]. Studies examining the influence of residential location on ... See full document

... Participants enrolled in the intervention arm have their plasma PlGF quantified in addition to routine hospital investigations. The PlGF result is made immediately available to the participants clinical team and docu- ... See full document

... Proportionate Review Sub-Committee of the National Research Ethics Service committees – North of Scotland (1) has reviewed this ...the trial will be submitted to the North of Scotland Research Ethics ... See full document

... the trial registration information and what is reported in the final SWD trial reports; and 6) to assess the consistency of what is reported in the abstracts and main text of the SWD trial ...the ... See full document

... hierarchical design (patients nested within hospitals), multilevel linear and logistic re- gression analysis will be used to compare the outcomes between treatment groups, with age, sex, the American Society of ... See full document