[PDF] Top 20 Thyroid Stem Cells: Concept and Clinical Implications
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Thyroid Stem Cells: Concept and Clinical Implications
... Stem cells are fundamental cells from which all our cells arise or ‘stem’ ...undifferentiated cells have the properties to divide and thus renew themselves for very long period ... See full document
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Cancer stem cells – the current status of an old concept: literature review and clinical approaches
... cancer stem cell (CSC) hypothesis assumes that a tumour is hierarchically organized and not all of the cells are equally capable of generating descendants, similarly to normal ...only cells being ... See full document
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Clinical implications of the BRAF mutation in papillary thyroid carcinoma and chronic lymphocytic thyroiditis
... This study was conducted on 172 patients who had undergone total thyroidectomy or unilateral total thy- roidectomy for PTC; the patients were then examined for the BRAFV600E mutation using specimens obtained after ... See full document
6
Clinical applications of mesenchymal stem cells
... the clinical application of MSCs in this review. The first clinical trial using culture-expanded MSCs was carried out in 1995 and 15 patients became the recipients of the autologous cells ...of ... See full document
9
Hypoxia promotes thyroid differentiation of native murine induced pluripotent stem cells
... the thyroid related conditions during lifetime (Sewell et ...about stem cell technologies which can be the key tools for tissue engineering and regenerative medicine to treat this condition in the recent ... See full document
10
Aneuploidy in pluripotent stem cells and implications for cancerous transformation
... pluripotent stem cells (hPSCs), including embryonic stem cells (hESCs) derived from human blastocysts (Thomson et ...pluripotent stem cells (hiPSCs) generated through repro- ... See full document
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Epigenomics of human embryonic stem cells and induced pluripotent stem cells: insights into pluripotency and implications for disease
... epigenome has been largely acquired due to recent advances in next-generation sequencing technologies, such as ChIP-seq or MethylC-seq. Several chromatin features, including bivalent promoters, poised enhancers and ... See full document
13
Esophageal cancer stem cells and implications for future therapeutics
... ing pathway in ESCC through expressional analysis of the signaling target genes. Their results elucidated that HEY1 and HEY2 were significantly overexpressed in association with the clinicopathological features of ESCC ... See full document
8
A novel and generalizable organotypic slice platform to evaluate stem cell potential for targeting pediatric brain tumors
... that stem cells may be a rev- olutionary therapy for treatment of malignant brain tumors compared with traditional therapies of chemo- therapy, radiotherapy and ...potential clinical benefits of ... See full document
11
Governing stem cell therapy in India: regulatory vacuum or jurisdictional ambiguity?
... for stem cells in response to cri- ticisms that it does not have any internal evaluation mechanism (BioSpectrum India, 30 April ...for Stem Cell Research and Therapy (NAC-SCRT) to oversee and monitor ... See full document
22
Employment of the Triple Helix concept for development of regenerative medicine applications based on human pluripotent stem cells
... ated cells, as well as derivation of new hPSC lines of GMP ...and clinical development entails large resources and an organization to meet regulatory requirements, and is today probably best led by large ... See full document
7
Stem cells then, now and future!!
... unspecialized stem cells give rise to specialized cells, the process is called ...outside cells that trigger stem cell ...other cells, physical contact with neighboring ... See full document
6
Overcoming the lack of expression of the sodium iodide symporter protein in anaplastic thyroid cancer stem cells by targeting the phosphatidyl inositol 3 kinase signaling pathway
... expression. Several previous studies demonstrated that PI3K gene mutation has a notable role in promoting ATC (García- Rostán et al. 2005; Charles et al. 2014). Therefore, our results suggest that CD133 pos CSCs may have ... See full document
6
Stem cells in clinical practice: applications and warnings
... and clinical course ...the clinical seriousness ranging from asymptomatic severity to a fulminant and fatal ...effectors cells that have been recruited from the lung and cells resident in the ... See full document
20
Clinical translation of human neural stem cells
... label clinical study was conducted at Oregon Health and Science University by Drs Robert D Steiner and Nathan Selden to evaluate the safety of allo- geneic HuCNS-SC administration ... See full document
13
Unchain my heart: the scientific foundations of cardiac repair
... genitor cells, directly injected into the scarred region of the LV during open heart surgery for coronary artery bypass grafting ...hybrid cells formed by fusion with adjacent cardiomyocytes, which generate ... See full document
13
Potential and clinical utility of stem cells in cardiovascular disease
... of clinical trials after basic researchers and clinicians take account of the lessons learned from cell therapy trials ...germline stem cells (maGSCs) from mouse testis has opened another interesting ... See full document
8
Clinical course of thyroid function and thyroid associated-ophthalmopathy in patients with euthyroid Graves’ disease
... The one limitation of our study was that we used a non- standard method for evaluating the eye symptoms. Since the observation period for this study ranged from 1987 to 2017, the currently established and consistent ... See full document
8
Asymmetric distribution of pl10 and bruno2, new members of a conserved core of early germline determinants in cephalochordates
... eight cells (two different embryos shown, E and ...of cells of which two clearly express Vasa ...eight cells expressing ...Vasa-positive cells in the ventral endoderm on one side (G, arrow and ... See full document
12
Allhat in Perspective: Implications to Clinical Practice and Clinical Trials
... ALLHAT in Perspective Implications to Clinical Practice and Clinical Trials MOVING POINTS ALLHAT in Perspective Implications to Clinical Practice and Clinical Trials K Yusoff, FACC Faculty of Medicine[.] ... See full document
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