[PDF] Top 20 Tissue factor in tumor microenvironment: a systematic review
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Tissue factor in tumor microenvironment: a systematic review
... tor/pre-mRNA-splicing factor SF2 (ASF/SF2) and serine- rich protein55 (SRp55), leading to the generation of flTF mRNA and translation of the flTF isoform protein ...the factor X activated (FXa) generation ... See full document
8
Tissue engineering in periodontics: recent updates and systematic review
... specific tissue factors are not known, when a large tissue mass or organ is needed, or when tissue replacement must be ...a tissue-engineered skin equivalent. Skin is the first FDA approved ... See full document
6
Review Article The status and development of tumor microenvironment simulation platforms
... (1) Tumor cells, gases and nutrients are evenly distribut- ...system, tumor cells often are limited to the bottom of the system, and the interior lacks a sufficient number of ...normal tumor ... See full document
11
Osteoprotegerin rich tumor microenvironment: implications in breast cancer
... cancer tissue is a heterogeneous system, mainly composed of tumor epithelial cells and stromal ...the tumor microenvironment components including immune cells, mesenchymal stem cells (MSCs), ... See full document
15
Tumor suppressor ARF regulates tissue microenvironment and tumor growth through modulation of macrophage polarization
... transcription factor [11, ...suppress tumor growth through p53 regulation, numerous lines of evidence suggest that ARF has additional p53-independent tumor suppressor activities [5, ...the ... See full document
16
Interaction of tumor cells with the microenvironment
... in tumor tis- sues often correlates with poor prognosis for cancer patients ...on tumor growth and metasta- sis development reflect different states of activation acquired by TAMs in the tumor ... See full document
8
Co evolution of cancer microenvironment reveals distinctive patterns of gastric cancer invasion: laboratory evidence and clinical significance
... in tumor cell inva- sion into surrounding normal tissues [24,25], including expression of growth factors, matrix proteases, promo- tion of angiogenesis and suppression of adaptive immu- nity, all of which ... See full document
11
Native-mimicking in vitro microenvironment: an elusive and seductive future for tumor modeling and tissue engineering
... cells, tissue specific cells and migratory cells, on the other hand, modify local ECM microenvironment to make it serve the best for cellular ...between tissue-specific cells and ECM are thus vital ... See full document
22
The prognostic value of tumor infiltrating lymphocytes in colorectal cancer differs by anatomical subsite: a systematic review and meta analysis
... respectively. Initially, 23 studies involving a total of 4731 patients were identified. Among them, 19 were colon cancer studies and six studies were related to rectal can- cer. One study did not have sufficient data, ... See full document
11
The Importance of Controlling the TGF-β Signaling Pathway in the Gastric Cancer Microenvironment
... Numerous excellent reviews extensively cover TGF-β signal transduction [14-17]. Briefly, the TGF-β superfamily comprises more than 30 different members, including the TGF-βs (comprising the three highly homologous ... See full document
13
Tumor Hypoxia Regulates Forkhead Box C1 to Promote Lung Cancer Progression
... in tumor progression. However, the role of tumor hypoxia in FOXC1 regulation and its impact on lung cancer progression are ...hypoxia-inducible factor-1 α (HIF-1 α ) to the hypoxia-responsive element ... See full document
15
Modulation of monocyte matrix metalloproteinase 2 by breast adenocarcinoma cells
... in tumor cell invasion and metastasis, may be enhanced by soluble factors from breast cancer ...While tumor cells have been extensively studied, the roles of monocytes in the tumor ... See full document
8
A Review of Exosomes and their Role in The Tumor Microenvironment and Host-Tumor "Macroenvironment"
... factors. Tumor-derived exosomes (TEX) have profound impact on the immediate tumor microenvironment ...distant tissue sites to create a pre-metastatic niche conducive to metastasis, which we ... See full document
5
Next generation tissue microarray (ngTMA) increases the quality of biomarker studies: an example using CD3, CD8, and CD45RO in the tumor microenvironment of six different solid tumor types
... normal tissue (n = 1), tumor center (n = 2), tumor front (n = 2), and tumor microenvironment at invasion front (n = 2) for subsequent ...420 tissue cores created two ngTMA ...the ... See full document
7
A review of the development of tumor vasculature and its effects on the tumor microenvironment
... host tissue. Capillaries sprout toward the tumor and anastomose with each other and the host vessels to form a capillary net- work through the ...the tumor periphery to facilitate its increase in ... See full document
12
Intravenous somatic gene transfer with antisense tissue factor restores blood flow by reducing tumor necrosis factor induced tissue factor expression and fibrin deposition in mouse meth A sarcoma
... of tissue factor in endothelium. Although induction of tissue factor in cultured endothelial cells has been demon- strated by many groups, investigation of human atheroscle- rotic plaques and ... See full document
13
Evaluating the predictive value of biomarkers for efficacy outcomes in response to pertuzumab and trastuzumab based therapy: an exploratory analysis of the TRYPHAENA study
... In addition to HER2, a number of components from the HER signaling pathways and other signaling pathways have previously been suggested to predict responsiveness (or lack of ) to HER-targeted agents, including phos- ... See full document
12
The role of microenvironment in tumor angiogenesis
... A murine model for MM indicates that the switch is preceded by the expression of mRNA for VEGF and secre- tion of the protein by plasma cells, and by a shift from CD45 positive to CD45 negative plasma cells that are the ... See full document
6
Immune reprogramming via PD-1 inhibition enhances early-stage lung cancer survival
... matching tumor growth and principle component analysis analyses: IgG2a-treated progressing tumors (group 1), early anti–PD-1–treated regressing tumors (group 2), early anti– PD-1–treated progressing tumors (group ... See full document
22
Effect of Cyclosporin a on the Tumor Microenvironment
... several tumor types in a cell autonomous ...multiform tumor cell survival by stabilizing the oncogenic proteins myc and p53, likely through its chaperone activity (Choi et ... See full document
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