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[PDF] Top 20 Transcriptome sequencing identified hub genes for hepatocellular carcinoma by weighted-gene co-expression analysis

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Transcriptome sequencing identified hub genes for hepatocellular carcinoma by weighted-gene co-expression analysis

Transcriptome sequencing identified hub genes for hepatocellular carcinoma by weighted-gene co-expression analysis

... We identified 15 highly connected hub genes in MEtan, including ABCA8, AFP, EGR3, EXO1, HMGA1, MT1X and VARS, which play roles as major regulators in cell-cycle regulation and cancer ... See full document

13

Co-expression network analysis identified FCER1G in association with progression and prognosis in human clear cell renal cell carcinoma

Co-expression network analysis identified FCER1G in association with progression and prognosis in human clear cell renal cell carcinoma

... technology, gene expression profiles have been used to identify genes associated with progression of renal cancer ...expressed genes and ignored the high degree of interconnection between ... See full document

12

Identification of novel long non-coding RNAs deregulated in hepatocellular carcinoma using RNA-sequencing

Identification of novel long non-coding RNAs deregulated in hepatocellular carcinoma using RNA-sequencing

... Abnormal expression of a few long non-coding RNAs have been found associated with hepatocellular carcinoma, with potential implications to both improve our understanding of molecular mechanism of ... See full document

16

Identification and interaction analysis of key genes and microRNAs in hepatocellular carcinoma by bioinformatics analysis

Identification and interaction analysis of key genes and microRNAs in hepatocellular carcinoma by bioinformatics analysis

... and analysis of modules Ninety-seven nodes and 319 edges were mapped in the PPI network of identified DEGs, including 43 up-regulated genes and 54 down-regulated genes ...as hub ... See full document

9

Whole-transcriptome sequencing identified gene expression signatures associated with aggressive clear cell renal cell carcinoma

Whole-transcriptome sequencing identified gene expression signatures associated with aggressive clear cell renal cell carcinoma

... of genes identified by Brannon et al ...in gene expression platform used by Brannon (microarray) and the targeted sequencing TempO-Seq assay, and differences introduced by using ... See full document

10

<p>Super-Enhancer-Associated Hub Genes In Chronic Myeloid Leukemia Identified Using Weighted Gene Co-Expression Network Analysis</p>

<p>Super-Enhancer-Associated Hub Genes In Chronic Myeloid Leukemia Identified Using Weighted Gene Co-Expression Network Analysis</p>

... NCBI Gene Expression Omnibus (GEO) ...Human Transcriptome Array 2.0 platform [transcript (gene) ...an expression matrix and all probes matched to their gene symbol using the R ... See full document

14

Systematically characterizing dysfunctional long intergenic non- coding RNAs in multiple brain regions of major psychosis

Systematically characterizing dysfunctional long intergenic non- coding RNAs in multiple brain regions of major psychosis

... RNA sequencing on 82 post- mortem brain tissues from three brain regions (orbitofrontal cortex (BA11), anterior cingulate cortex (BA24) and dorsolateral prefrontal cortex (BA9)) of patients with SZ and BD and ... See full document

12

An integrated analysis for long noncoding RNAs and microRNAs with the mediated competing endogenous RNA network in papillary renal cell carcinoma

An integrated analysis for long noncoding RNAs and microRNAs with the mediated competing endogenous RNA network in papillary renal cell carcinoma

... cell carcinoma (PRCC) is the second most common subtype of renal cell carcinoma, and it lacks effective therapeutic targets and prognostic molecular ...integrated expression profiles, including data ... See full document

14

Ten hub genes associated with progression and prognosis of pancreatic carcinoma identified by co-expression analysis

Ten hub genes associated with progression and prognosis of pancreatic carcinoma identified by co-expression analysis

... from Gene Expression Omnibus (GEO) database ...construct co-expression networks and identify hub genes in our study ...pancreatic carcinoma from The Cancer Genome Atlas ... See full document

13

Transcriptome integration analysis in hepatocellular carcinoma reveals discordant intronic miRNA-host gene pairs in expression

Transcriptome integration analysis in hepatocellular carcinoma reveals discordant intronic miRNA-host gene pairs in expression

... host genes, are thought to be co-transcribed from their host genes and present consistent expression patterns with host ...discordant expression with their host ...the expression ... See full document

12

Identification of biomarkers of chromophobe renal cell carcinoma by weighted gene co-expression network analysis

Identification of biomarkers of chromophobe renal cell carcinoma by weighted gene co-expression network analysis

... between genes and phenotypes. This method is able to transform gene expression data into co-expression modules and provide insights into signaling networks that may be responsible for ... See full document

12

Role of p53 in pseudorabies virus replication, pathogenicity, and host immune responses

Role of p53 in pseudorabies virus replication, pathogenicity, and host immune responses

... Total RNA from the brains or cells was extracted using the TRIzol extraction method (TRIzol reagent, TaKaRa Japan). The procedures for RNA isolation and purifi- cation, as well as the on-column deoxyribonuclease ... See full document

12

&lt;p&gt;Bioinformatics Analysis and RNA-Sequencing of SCAMP3 Expression and Correlated Gene Regulation in Hepatocellular Carcinoma&lt;/p&gt;

<p>Bioinformatics Analysis and RNA-Sequencing of SCAMP3 Expression and Correlated Gene Regulation in Hepatocellular Carcinoma</p>

... and expression of various genes involved in ...Exome sequencing revealed that frequent inactivating mutations in ARID4 existed in microsatellite unstable colorectal ...PPAP2B expression to ... See full document

11

&lt;p&gt;Identification of hub genes and key pathways associated with angioimmunoblastic T-cell lymphoma using weighted gene co-expression network analysis&lt;/p&gt;

<p>Identification of hub genes and key pathways associated with angioimmunoblastic T-cell lymphoma using weighted gene co-expression network analysis</p>

... cant hub genes according to fi ve algorithms (Subgraph, Degree, Eigenvector, Betweenness, and ...key genes were discovered from the top 100 genes in CytoHubba and ...key genes were ... See full document

12

Bladder cancer stage-associated hub genes revealed by WGCNA co-expression network analysis

Bladder cancer stage-associated hub genes revealed by WGCNA co-expression network analysis

... The gene chip GSE31684, including 93samples, was downloaded from the GEO datasets and co-expression network was constructed by the ...identify hub genes. The most significant cluster ... See full document

11

&lt;p&gt;Decreased PTGDS Expression Predicting Poor Survival of Endometrial Cancer by Integrating Weighted Gene Co-Expression Network Analysis and Immunohistochemical Validation&lt;/p&gt;

<p>Decreased PTGDS Expression Predicting Poor Survival of Endometrial Cancer by Integrating Weighted Gene Co-Expression Network Analysis and Immunohistochemical Validation</p>

... four genes were validated using the GEPIA database, when compared with normal endometrial tissue, LGR5 and SST were signi fi cantly upregulated in EC tissue, and ZNF558 and PTGDS were signi fi cantly down- regulated ... See full document

19

Analysis of novel caudal hindbrain genes reveals different regulatory logic for gene expression in rhombomere 4 versus 5/6 in embryonic zebrafish

Analysis of novel caudal hindbrain genes reveals different regulatory logic for gene expression in rhombomere 4 versus 5/6 in embryonic zebrafish

... additional genes acting within the caudal hindbrain ...other genes acting in the caudal hindbrain ...has identified additional genes expressed in the caudal ...these genes may have ... See full document

24

Generation of a non-small cell lung cancer transcriptome microarray

Generation of a non-small cell lung cancer transcriptome microarray

... cDNA sequencing (Figure 2A). This was followed by expression data-derived sequences (32%) and public database sequences identified while extending 3' termini of 5' EST assembly and expression ... See full document

12

Identification of glioblastoma gene prognosis modules based on weighted gene co-expression network analysis

Identification of glioblastoma gene prognosis modules based on weighted gene co-expression network analysis

... the genes in this model, OSMR and SOX21 have been previously reported in glioblastoma studies ...[29], expression level of OSMR was higher in mesenchymal and classical subtypes than proneural ...Each ... See full document

12

MicroRNAs in Nonalcoholic Fatty Liver Disease

MicroRNAs in Nonalcoholic Fatty Liver Disease

... and gene regulatory ...between genes and miRNAs indicate that we may not be able to decipher the biological role of any miRNA species in ...high-throughput sequencing approaches to the ... See full document

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