[PDF] Top 20 Transcriptome sequencing reveals thousands of novel long non-coding RNAs in B cell lymphoma
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Transcriptome sequencing reveals thousands of novel long non-coding RNAs in B cell lymphoma
... characterize novel lncRNAs in DLBCL using a de novo transcript discovery strategy based on RNAseq of primary DLBCLs and normal B cell ...of coding properties, length, exon counts, and ... See full document
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Integrative transcriptome analysis suggest processing of a subset of long non-coding RNAs to small RNAs
... intergenic non-coding RNAs (lincRNAs) ...deep sequencing of transcriptome [6] and computational tools to under- stand transcript diversity, structure and expression has led to the ... See full document
13
Novel classes of non coding RNAs and cancer
... of non-transcribed pseudogenes, or formation of pseudo- genes transcribed into RNAs ...these RNAs exhibit a tissue-specific pattern of acti- ...interfering RNAs that regulate coding ... See full document
21
Identification of novel long non-coding RNAs deregulated in hepatocellular carcinoma using RNA-sequencing
... of long non-coding RNAs (lncRNAs) and their pathological relevance is still a challenging ...few long non-coding RNAs have been found associated with hepatocellular ... See full document
16
Long non-coding RNAs defining major subtypes of B cell precursor acute lymphoblastic leukemia
... Importantly, apoptosis suppressor lncRNA in Myc-driven lymphomas miR-17/92 cluster host gene (MIR17HG) [52] is upregulated in relapsed samples within the Ph-like subtype and downregulated in re- lapsed samples within ... See full document
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Ribosome profiling reveals resemblance between long non coding RNAs and 5′ leaders of coding RNAs
... no novel junctions; –M; –g 10) to a zebrafish developmental transcriptome (Pauli et ...the coding sequences, RPFs between 27 and 32 nts (totaling 220 million) were deemed to be high quality and were ... See full document
7
Abstract: Long non-coding RNAs (lncRNAs) are a novel class of regulatory RNA molecules and they
... Similar to mRNA, the mechanisms of biogenesis of lncRNAs are also gradually uncovered. Nowadays, most of the lncRNAs are usually transcribed by RNA polymerase-II (pol II), and then capped at 5 0 -end, spliced and ... See full document
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Identification and functional analysis of long non-coding RNAs in human and mouse early embryos based on single-cell transcriptome data
... The novel lncRNAs were obtained by the following steps: (1) Cuffcompare in Cufflinks was run using default parameters (and ‘-M discard (ignore) single-exon transfrags and reference transcripts’) to combine our ... See full document
14
Integrative Deep Sequencing of the Mouse Lung Transcriptome Reveals Differential Expression of Diverse Classes of Small RNAs in Response to Respiratory Virus Infection
... of long non-protein-coding RNAs (ncRNAs) in response to virus ...RNA transcriptome sequencing analysis of the host response to both severe acute respiratory syndrome coronavirus ... See full document
11
Long non-coding RNAs as novel players in β cell function and type 1 diabetes
... Capture Sequencing (CaptureSeq) [92], coupling of rapid ampli- fication of cDNA ends (RACE) technique to long-read se- quencing (RACE-Seq) [93], RNA Capture Long Seq (CLS) [94], and genome-scale ... See full document
10
Single cell analysis of long non coding RNAs in the developing human neocortex
... novo transcriptome assembly was performed separately on rRNA depletion total RNA-seq align- ments, and on polyA selection RNA-seq alignments, using Cufflinks ...as novel transcripts [52]. ... See full document
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<p>Long Noncoding RNAs in Diffuse Large B-Cell Lymphoma: Current Advances and Perspectives</p>
... DLBCL transcriptome and provides an abundant informa- tion source for further ...GCB-DLBCL cell lines (OCI-ly1 and OCI- ly19) and normal B lymphocytes, and their data revealed that 1648 lncRNAs were ... See full document
9
Transcriptome sequencing reveals altered long intergenic non coding RNAs in lung cancer
... in non-small cell lung cancer ...in non-small cell lung cancer patients with and without metastatic tumors ...intronic non-coding RNA (ncRNA) lncRNA-LET plays a role in the ... See full document
16
Long non-coding RNAs in ovarian cancer
... parallel sequencing technology [6, 7], it has been well accepted that more than 98% of the human genome is transcribed into RNA transcripts that do not have apparent protein-coding ...ing RNAs ... See full document
13
Identification of novel long non-coding RNAs in triple-negative breast cancer
... To predict the functions of the lncRNAs, we adopted method originally demonstrated in this paper[10]. Briefly, we first calculated the co-expressed mRNAs for each of the differentiated lncRNAs, and then we conducted a ... See full document
10
Integrative analysis of protein-coding and non-coding RNAs identifies clinically relevant subtypes of clear cell renal cell carcinoma
... noncoding RNAs, including miRNAs and long non-coding RNAs (lncRNAs), can be important epigenetic regulators of various biological processes through transcriptional and ... See full document
15
Integrated TCGA analysis implicates lncRNA CTB-193M12.5 as a prognostic factor in lung adenocarcinoma
... RNA sequencing technology has greatly facilitated identifying lncRNAs associated with various ...throughput sequencing of transcriptomes at single-base resolution, whose quantification across experiments ... See full document
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Long non-coding RNAs in the regulation of myeloid cells
... myeloid cell development fac- tors targeted by RA ...ATRA-induced cell cycle arrest. Along with resistance to arrest of cell cycle progression, HOTAIRM1 knockdown alters ATRA- induced changes in ... See full document
12
An overview of long non-coding RNAs in ovarian cancers
... cancer cell lines reduced proliferation, migration and invasion in vitro, as well as tumor burden in vivo in a xenograft model with C13 ...of coding potential for HOXA11-AS, understanding why the “A” and ... See full document
16
Role of Long Non coding RNAs in Sculpting Neurons
... protein coding genes, whereas non- coding portion of the genome has undergone substantial ...to non-coding RNAs (ncRNAs) that lead to increased biological ...generation ... See full document
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