[PDF] Top 20 3,5,6 Trimethylthieno[2,3 d]pyrimidin 4(3H) one
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![3 Benzyl 2 butylamino 5,6,7,8 tetrahydrobenzothieno[2,3 d]pyrimidin 4(3H) one](data:image/gif;base64,R0lGODlhAQABAIAAAP///wAAACH5BAEAAAAALAAAAAABAAEAAAICRAEAOw==)
3 Benzyl 2 butylamino 5,6,7,8 tetrahydrobenzothieno[2,3 d]pyrimidin 4(3H) one
... Ph—CH2), 4.35 (br, 1H, NH), 3.32–3.30 (m, 2H, NCH2), 2.99–2.69 (m, 4H, 2CH2), 1.86–1.84 (m, 4H, 2CH2), 1.39–1.35 (m, 2H, CH2), 1.15–1.05 (m, 2H, CH2), 0.82–0.78 (t, J = 7.4 Hz, 3H, CH3); MS (m/z, %), 367(M+, 7), 277 ... See full document
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5 Methyl 2 (2 nitrophenyloxy) 3 p tolyl 8,9,10,11 tetrahydrobenzo[4′,5′]thieno[3′,4′:5,6]pyrido[4,3 d]pyrimidin 4(3H) one
... In (I) (Fig. 1), the C—S bond lengths are longer than those observed in free thiophene [1.714 (3) A ˚ ; Bonham & Momany, 1963] and thieno-[2,3-c]-pyridine [1.728 (1) and 1.731 (1) A ˚ ; Nerenz et al., ... See full document
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2 (4 Chloro 3 methylphenoxy) 3 (4 chlorophenyl) 5 methyl 8,9,10,11 tetrahydro 1 benzothieno[2′,3′:2,3]pyrido[4,3 d]pyrimidin 4(3H) one dichloromethane solvate
... [1.744 (5) and 1.745 (5) A ˚ ] are equivalent and long compared with the values observed in both free thiophene, measured using electron diffraction, and thieno[2,3-c]pyridine. The central ... See full document
9
2 (2,4 Dichloro 6 methylphenoxy) 3 isopropyl 5,6,7,8 tetrahydrobenzothieno[2,3 d]pyrimidin 4(3H) one
... In the fused heterobicyclic ring system of (I), bond lengths and angles (Table 1) are similar to those observed in closely related structures (Zeng et al., 2006a,b). All ring atoms in the thienopyrimidine system are ... See full document
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3 (4 Fluorophenyl) 2 (4 methylphenoxy) 5,8,9 trimethylthieno[3′,2′:5,6]pyrido[4,3 d]pyrimidin 4(3H) one
... N2 0.0481 (10) 0.0449 (10) 0.0408 (9) −0.0012 (8) 0.0180 (8) −0.0045 (8) N3 0.0442 (10) 0.0491 (11) 0.0561 (11) −0.0009 (8) 0.0210 (9) 0.0041 (9) O1 0.0712 (10) 0.0786 (12) 0.0558 (9) −0.0073 (9) 0.0373 (9) −0.0128 (8) ... See full document
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5 Methyl 2 morpholino 3 p tolyl 8,9,10,11 tetrahydro 2 benzothieno[2′,3′:6,5]pyrido[4,3 d]pyrimidin 4(3H) one
... Selected bond lengths and angles are listed in Table 1. In (I) (Fig. 1), the C—S bonds are longer than those observed in free thiophene [1.714 (3) A ˚ ; Bonham & Momany, 1963] and thieno[2,3-c]pyridine ... See full document
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3 Amino 2 methyl 5,6,7,8 tetrahydro 1 benzothieno[2,3 d]pyrimidin 4(3H) one
... 1973). Thieno[2,3-d]pyrimidine and 2-aminothiophene derivatives possess platelet aggregation inhibition (Kikugawa & Ichino, 1973) and antitumor activities (Patil et ... See full document
6
2 Dipropylamino 6 methyl 5 (4 methylphenyl) 3,8 diphenyl 5,8 dihydropyrazolo[4′,3′:5,6]pyrano[2,3 d]pyrimidin 4(3H) one
... C4 0.066 (2) 0.108 (3) 0.066 (2) 0.028 (2) 0.0069 (17) 0.051 (2) C5 0.059 (2) 0.087 (2) 0.074 (2) 0.0262 (17) 0.0138 (16) 0.0506 (19) C6 0.0464 (17) 0.0666 (18) ... See full document
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3 (2 Aminophenyl) 2 methylsulfanyl 5,6,7,8 tetrahydrobenzothieno[2,3 d]pyrimidin 4(3H) one
... (10 ml) was stirred for 1 h at room temperature and filtered. The filtrate was concentrated and the precipitate was recrystallized from methylene chloride/petroleum ether (1:3 v/v) to give compound (I) in 80% ... See full document
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2 (4 Chlorophenoxy) 3 isopropyl 5,6,7,8 tetrahydro 2 benzothieno[2,3 d]pyrimidin 4(3H) one
... C1 0.0428 (13) 0.0616 (18) 0.0575 (15) 0.0018 (12) 0.0261 (11) −0.0039 (13) C2 0.066 (2) 0.117 (3) 0.097 (3) −0.008 (2) 0.047 (2) −0.038 (3) C3 0.080 (2) 0.084 (3) ... See full document
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2 Ethoxy 3 phenyl 1 benzothieno[3,2 d]pyrimidin 4(3H) one
... C1 0.0359 (7) 0.0508 (8) 0.0362 (6) −0.0060 (5) 0.0216 (6) −0.0048 (5) C2 0.0402 (7) 0.0582 (9) 0.0459 (7) 0.0015 (6) 0.0233 (6) −0.0045 (6) C3 0.0397 (8) 0.0809 (12) ... See full document
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2 Diethylamino 3 (3 methylphenyl) 1 benzofuro[3,2 d]pyrimidin 4(3H) one
... g, 3 mmol) in dry dichloromethane (15 ml) was added phenyl isocyanate (3 mmol) under nitrogen at room ...for 3 h at room temperature, concentrated under reduced pressure and the residue ... See full document
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SYNTHESIS AND ANTICONVULSANT ACTIVITY OF SOME NEW 1, 6 DIPHENYL 10, 10a DIHYDROPYRIDO[2, 3 d] 1, 2, 4 TRIAZOLO [4, 3 a]PYRIMIDIN 5(1H) ONE DERIVATIVES
... compound 2- thioxo-1,3-dihydropyridino[2,3-d] pyrimidin-4(1H)-one were obtained by reacting enaminones with 6-amino-2-thioxo-2, ... See full document
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3 (4 Methylphenyl) 2 morpholinobenzo[4,5]furo[3,2 d]pyrimidin 4(3H) one
... C1 0.0661 (12) 0.0537 (11) 0.0534 (10) 0.0163 (10) 0.0388 (10) 0.0128 (9) C2 0.0886 (16) 0.0629 (13) 0.0627 (13) 0.0291 (12) 0.0513 (13) 0.0215 (10) C3 0.0711 (15) 0.0834 (16) 0.0581 (13) 0.0401 (13) 0.0368 (12) 0.0308 ... See full document
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Synthesis and pharmacological screening of 5-methyl-3-[ P -(6'-aryl-2'-thioxo-1',2',5',6'-tetrahydro-pyrimidin-4'-yl)-phenyl]-3 H -2-oxo-D4-1,3,4-oxadiazoles
... to 4-bromo-3- (P-acetyl)-phenylsydnone 5, which upon treatment with aromatic aldehydes 2a-d in ethanol, afforded 4-bromo-3-[P-(3'-aryl-acryl-1'-oyl)] phenylsydnone ...to ... See full document
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2 Ethylamino 3 phenyl 2 benzothieno[3,2 d]pyrimidin 4(3H) one
... C1 0.0579 (12) 0.0575 (13) 0.0524 (11) −0.0075 (10) 0.0145 (10) −0.0032 (10) C2 0.0662 (14) 0.0751 (16) 0.0613 (13) −0.0096 (12) 0.0192 (11) 0.0013 (12) C3 0.0855 (18) 0.092 (2) 0.0712 (16) −0.0130 (15) 0.0220 ... See full document
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Synthesis and antibacterial activity of 3-amino-6-iodo-2-methyl quinazolin 4-(3H)-one and 6-iodo-2-methyl-4H-benzo [D] [1, 3] oxazin-4-one
... of 2-amino substituent is a successful strategy to improve the chemical stability of ...of 4(3H)-quinazolinone derivatives, 2,3-disubstituted derivative of quinazoline- 4-one were synthesized ... See full document
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2 Ethoxy 3 isopropylbenzo[4,5]thieno[3,2 d]pyrimidin 4(3H) one
... C5 0.0393 (12) 0.0536 (14) 0.0396 (12) 0.000 −0.0018 (9) 0.000 C6 0.0411 (12) 0.0408 (12) 0.0317 (11) 0.000 −0.0025 (8) 0.000 C7 0.0379 (11) 0.0398 (12) 0.0317 (10) 0.000 0.0005 (8) 0.000 C8 0.0455 (13) 0.0517 (14) ... See full document
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Cyclohexanespiro 2′ [2′,3′,6′,7′ tetrahydro 1′H cyclopenta[d]pyrimidin] 4′(5′H) one
... Fig. 2 and have a similar conformation as (s)-2-(3-nitrophenyl)-1,2-dihydro-quinazolin-4(3H)-one (Zhang, Li & Shi et ...in 4(3H)-quinazolinone derivatives (Zhang, Li & ... See full document
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2 (Dibutylamino) 3 (4 fluorophenyl) 5,6,7,8 tetrahydro 7 methyl 6,8 diphenylpyridine[3′,4′:2,3]thieno[5,4 d]pyrimidin 4(3H) one
... The derivatives of heterocycles containing the thienopyrimidine system, which are well known bioisosteres of quinazolines, are of great importance because of their remarkable biological properties (Walter, 1999a; Walter, ... See full document
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