[PDF] Top 20 Variable Surface Epitopes in the Crystal Structure of Dengue Virus Type 3 Envelope Glycoprotein
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Variable Surface Epitopes in the Crystal Structure of Dengue Virus Type 3 Envelope Glycoprotein
... This structure (excluding the fucose) cor- responds to the pentasaccharide mannose 3 (Man3), which is the common core of all N-linked ...nine-mannose structure of high-mannose glycans to Man3 ...form ... See full document
9
Reevaluation of Amino Acid Variability of the Human Immunodeficiency Virus Type 1 gp120 Envelope Glycoprotein and Prediction of New Discontinuous Epitopes
... most variable regions in ...ous epitopes in this ...three-dimensional structure for this region was not solved, these sites were reported elsewhere to be included in the epitopes for ... See full document
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Characterization of Dengue Virus Complex-Specific Neutralizing Epitopes on Envelope Protein Domain III of Dengue 2 Virus
... of virus infectivity neutralized at particular relative occupancy levels) for the DENV complex-specific MAbs in this study was considerably less compared to previous data for a panel of DENV-2 ED3 ... See full document
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Introduction of Exogenous Epitopes in the Variable Regions of the Human Immunodeficiency Virus Type 1 Envelope Glycoprotein: Effect on Viral Infectivity and the Neutralization Phenotype
... HIV envelope following tagging depended on the position of the ...cell surface expression was unexpected, since this Env remains fusogenic even when major deletions are introduced into the V2 loop ... See full document
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Analysis of Individuals from a Dengue Endemic Region Helps Define the Footprint and Repertoire of Antibodies Targeting Dengue Virus 3 Type Specific Epitopes
... DENV envelope (E) protein is the major target of neutralizing antibodies (6), and its ectodomain is comprised of three domains: EDI, EDII, and ...facilitates virus attachment to host cells and subsequent ... See full document
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AB Initio Structural Analysis on Envelope (E) Glycoprotein of Dengue Virus (DENV) Type 1-4
... T-cell epitopes were located within conserved ...E glycoprotein structure was the most variable region of DENV, the conserved regions still can be ...E glycoprotein of all DENV ... See full document
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Crystal Structure of Dengue Virus Type 1 Envelope Protein in the Postfusion Conformation and Its Implications for Membrane Fusion
... Dengue virus, a member of the flavivirus family, imposes one of the largest social and economic burdens of any mosquito- borne viral pathogen (6, ...major envelope glycoprotein, E, and the ... See full document
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Structure of a Dengue Virus Envelope Protein Late-Stage Fusion Intermediate
... membrane-spanning envelope glycoprotein protein (E) of flaviviruses is both the principal determinant of icosahe- dral virion assembly and the fusion catalyst for merging viral and target cell membranes ... See full document
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Crystal Structure of West Nile Virus Envelope Glycoprotein Reveals Viral Surface Epitopes
... Nile virus E would be capable of forming a similar hydrophobic pocket, we compared the 12 hydrophobic residues that line the pocket in dengue virus sE along with their West Nile virus homologs ... See full document
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Type- and Subcomplex-Specific Neutralizing Antibodies against Domain III of Dengue Virus Type 2 Envelope Protein Recognize Adjacent Epitopes
... secondary structure of DIII from the DENV-2 (strain 16681) E protein are aligned with those for DENV-1 (strain 16007), DENV-3 (strain 16652), DENV-4 (strain 1036), and WNV (New York ...secondary ... See full document
11
Hepatitis C Virus Envelope Glycoprotein E1 Forms Trimers at the Surface of the Virion
... helical structure align the two glycines on the same face of the helix, which creates a flat interaction platform allowing tight interhelical ...trimeric structure, the glycine residues of the GxxxG motif ... See full document
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Polytope Prediction for Dengue Vaccine Candidate Based on Conserved Envelope Glycoprotein of Four Serotypes of Dengue Virus and Its Antigenicity
... country. Dengue fever caused by dengue virus, has Envelope protein that often used for vaccine development to prevent the virus ...serotype dengue virus infection still ... See full document
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Isolation of the dengue virus envelope glycoprotein from membranes of infected cells by concanavalin A affinity chromatography.
... 3 mg of BHK cellular membrane protein per ml see 132 Downloaded from http://jvi.asm.org/ on November 10, 2019 by guest The membranes isolated from type 2 dengue virus-infected BHK-21/15 [r] ... See full document
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The Humoral Immune Response to Human T-Cell Lymphotropic Virus Type 1 Envelope Glycoprotein gp46 Is Directed Primarily against Conformational Epitopes
... recombinant envelope proteins, p21E and MTA-1 (11, ...B virus (HBV) core antigen, but not to the HBV surface ...immunodeficiency virus types 1 and 2 (HIV-1 and -2), HBV, and hepatitis C ... See full document
8
Reduced cell surface expression of processed human immunodeficiency virus type 1 envelope glycoprotein in the presence of Nef.
... 3274-3280 0022-538X/93/063274-07$02.00/0 Copyright 1993, American Society for Microbiology Reduced Cell Surface Expression of Processed Human Immunodeficiency Virus Type 1 Envelope Glyc[r] ... See full document
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Structure of Acidic pH Dengue Virus Showing the Fusogenic Glycoprotein Trimers
... The limited resolution of these results may be due of the lack of homogeneity when the pH is lowered and the temperature is in- creased (26). However, the spike formed by the E glycoproteins is clear and corresponds to a ... See full document
8
Replication and neutralization of human immunodeficiency virus type 1 lacking the V1 and V2 variable loops of the gp120 envelope glycoprotein.
... 4.2 envelope glycoproteins were produced in HeLa ...wild-type virus, the parental DV1/2 and revertant viruses were more sensitive to neutralization by antibody 17b, which recog- nizes a CD4i gp120 ... See full document
5
Mapping of the CXCR4 Binding Site within Variable Region 3 of the Feline Immunodeficiency Virus Surface Glycoprotein
... immunodeficiency virus (FIV) shares with T-cell tropic strains of human immunodeficiency virus type 1 (HIV-1) the use of the chemokine receptor CXCR4 for cellular ...FIV envelope ... See full document
9
Crystal structure of Usutu virus envelope protein in the pre fusion state
... Usutu virus (USUV) was first iden- tified in 1959 in South Africa [2, 32, ...the virus is closely related to Japanese encephalitis virus (JEV), West Nile virus (WNV) and Murray Valley ... See full document
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The Simian Immunodeficiency Virus Envelope Glycoprotein Contains Two Epitopes Presented by the Mamu-A*01 Class I Molecule
... smH4 envelope gp130 ectodomain, is designated ...be virus type-specific, as target cells sensitized with the SIVmac239 peptide TVPW- PNASL were not recognized ... See full document
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