[PDF] Top 20 Variation in red cell transfusion practice in the intensive care unit: a multicentre cohort study

... The authors wish to thank Diane Ferland, Merrilee Loewen, Debrah Foster, Denise Foster, Linda Knox and XiangRu Lu for their help in completing this project. We are also indebted to the nursing staff and all other health ... See full document

... our study contribute to the understanding of the effects of RBC transfusion on hemodynamic param- ...for study mea- surements, our approach does not allow drawing definite conclusions about the ... See full document

... pathophysiological study, and our re- sults have to be interpreted with ...RBC transfusion impacts on microvascular reactiv- ity, but our small sample size study was not designed to evaluate the ... See full document

... and transfusion of a single unit of PRBC is associated with a 10% increase in hospitali- zation costs [ 29 ...single unit of leukoreduced PRBC and FFP at the time of the study were $183 and ... See full document

... RBC, red blood cell; NICU, neonatal intensive care unit; SNAP, Score for Neonatal Acute Physiology; PRBC, packed red blood cells; GA, gestational ...receiving red blood ... See full document

... SOAP cohort, RBC transfusion was asso- ciated with improved outcome ...a cohort of patients with community-acquired severe sepsis from multiple ICUs ...of intensive care. The problem is ... See full document

... by study design, a causal relationship could not be deter- ...of transfusion-related complications, the potential confounders for death were not fully adjus- ted and may not all be included in our ... See full document

... Packed red blood cell (PRBC) transfusion is required in hematology patients treated with chemotherapy for acute leukemia, autologous (auto) or allogeneic (allo) hematopoietic stem cell ... See full document

... a transfusion being recorded varies over time or according to the severity of the patient’s ...of transfusion reporting across databases allows the extent of over- and under-reporting to be ...Neonatal ... See full document

... receiving red blood cell ...and red blood cell transfusions are administered with the intention of increasing haemoglobin level and thus oxygen ...with red blood cell ...early ... See full document

... The practice of transfusion is in ...notable study to date, a randomised controlled trial of liberal versus conservative red blood cell use [6], demonstrated that, for patients who were ... See full document

... Each globin chain encloses a single heme moiety, which consists of a protoporphyrin IX ring complexed with an iron atom in its ferrous state (Fe 2+ ). Every heme moiety has the capacity to bind to a single molecule of ... See full document

... blood transfusion status, that is, need for blood transfusion as the depen- dent ...blood transfusion at any time with individual patients who did not, based on propensity ...blood transfusion ... See full document

... ACCEPTED MANUSCRIPT short term patient survival but does not impact longer term renal outcome, which is in contrast to non-ICU populations (23). It is important to recognise that clinically, AKI in the setting of ICU is ... See full document

... RBC transfusion in patients with circulatory shock after volume ...from transfusion was defined as an improvement in tissue oxygen utilization (increased oxygen consumption 关V˙ O 2 兴 or decreased lactate), ... See full document

... of transfusion practice in palliative care that we have not ...blood transfusion, so we cannot draw conclusions about whether actual harm came to any of our ... See full document

... best practice recommendations for stroke care (updated ...of Care Outcomes in Research Interdisciplinary Working Groups: Guidelines for the early management of adults with ischemic stroke: a ... See full document

... Furthermore, despite the high response rate, the statistical analyses are likely to be influenced by a lack of power. The lack of power might have obscured other possible effects of ICU organization on hospital ... See full document

... Are transfusion ‘thresholds’ the best determinant of the need for transfusion? While the adoption of specific transfusion thresholds can prevent over- utilisation of blood products, it is equally ... See full document

... the study include an inability to include all ICUs, and in relation to interhospital transfers an inability to define the selection process leading to ...the study, four centres were unable to complete the ... See full document