[PDF] Top 20 In Vitro and Animal Models of Human Immunodeficiency Virus Infection of the Central Nervous System
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In Vitro and Animal Models of Human Immunodeficiency Virus Infection of the Central Nervous System
... culture system of the human fetal CNS. This system allows for the development of many of the same cell contacts that would be developed in ...this system, they documented the differentiation ... See full document
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Central Nervous System Inflammation and Infection during Early, Nonaccelerated Simian-Human Immunodeficiency Virus Infection in Rhesus Macaques
... In vitro experiments also provided evidence against the hypothesis that the lack of increase in monocytes/ macrophages was due to the inability of SHIV-1157ipd3N4 to infect these ...productive infection, ... See full document
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Neurovirulent simian immunodeficiency virus replicates productively in endothelial cells of the central nervous system in vivo and in vitro.
... SIVmac239/17E-Br employs to gain entry to macaque brain endothelial cells will be vital for assessing the role that endothelial cell infection with a murine leukemia virus.. lentivirus i[r] ... See full document
7
In vivo transcriptional regulation of the human immunodeficiency virus in the central nervous system in transgenic mice.
... In vitro studies of the CNS have identified regions of the HIV LTR which may contribute to transcription (49, 74, 75, ...in vitro studies with the NTERA-1 carcinoma cell line induced to differentiate into ... See full document
9
Central nervous system-derived cells express a kappa B-binding activity that enhances human immunodeficiency virus type 1 transcription in vitro and facilitates TAR-independent transactivation by Tat.
... 6 0022-538X/94/$04.00+0 Copyright © 1994, American Society for Microbiology Central Nervous System-Derived Cells Express a KB-Binding Activity That Enhances Human Immunodeficiency Virus [r] ... See full document
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Understanding the MIND phenotype: macrophage/microglia inflammation in neurocognitive disorders related to human immunodeficiency virus infection
... in human tissues, and particularly in the brain under normal, disease, or injurious ...primate models for human immunodeficiency virus have been extremely useful for understanding the ... See full document
8
STAT1 Signaling in Astrocytes Is Essential for Control of Infection in the Central Nervous System
... the central nervous system (CNS) ...murine models of toxoplasmic encephalitis (TE), astrocyte activation and proliferation are prominent, and these cells produce chemokines that can influence ... See full document
15
Novel mechanisms of central nervous system damage in HIV infection
... Abstract: Human immunodeficiency virus-1 infection of the central nervous system is an early event after primary infection, resulting in motor and cognitive defects ... See full document
11
The Majority of CD4+ T-Cell Depletion during Acute Simian-Human Immunodeficiency Virus SHIV89.6P Infection Occurs in Uninfected Cells
... competing models with nonlinear least-squares and Akaike information criteria (AIC) (33) (see the ...inhibits infection of primary cells both in vivo and in ...reporter virus encoding luciferase (2 ... See full document
11
Primary human immunodeficiency virus type 1 viremia and central nervous system invasion in a novel hu-PBL-immunodeficient mouse strain.
... viral infection model for the human im- mune system using small animals is important in biomedical research, especially in studies of human immunodeficiency vi- rus type 1 (HIV-1) ... See full document
8
Tristetraprolin expression and microRNA-mediated regulation during simian immunodeficiency virus infection of the central nervous system
... SIV infection in macaques (Figure 1A), comparing control, uninfected animals with acute (4, 7, 10 dpi), persistent/asymptomatic (14, 21 dpi), and late-stage infection (42, 56, 84 ...acute infection ... See full document
10
Proton MR spectroscopy of brain abnormalities in neonates born to HIV positive mothers
... Evidence of early central nervous system involvement in the acquired immunodeficiency syndrome AIDS and other human immunodeficiency virus HIV infections: studies with neuropsychologic t[r] ... See full document
7
Molecular Diagnosis of Herpes Simplex Virus Infections in the Central Nervous System
... (HIV-1) infection, both in vitro and in vivo, has been associated with an internal 32-bp deletion in the human CC-chemokine receptor 5 gene (23, 87) and mutations in the promoter region which are ... See full document
10
Transmission of Simian Immunodeficiency Virus SIVcpz and the Evolution of Infection in the Presence and Absence of Concurrent Human Immunodeficiency Virus Type 1 Infection in Chimpanzees
... chimeric virus derived from vi- ruses found in monkey species known to be preyed upon by chimpanzees (1, ...recombinant virus is that at least one chimpanzee became infected with one of these two viruses ... See full document
11
Fighting the Monster: Applying the Host Damage Framework to Human Central Nervous System Infections
... CNS infection was intact but brain histopathology demonstrated an M2 macrophage polarization (CD68 ⫹ CD200R1 ⫹ ) and poor phagocytosis of fun- gal cells, as identified by calcafluor white staining ... See full document
13
Decreases in human immunodeficiency virus infection rates in Kombolcha, Ethiopia: a 10-year data review
... HIV infection was 10.8% (2,233/20,674). The rate of infection varied from ...HIV infection significantly reduced in the last 10 years in Kombolcha ...HIV infection still remains high ... See full document
6
Psychiatric Co-Morbidity in People with HIV/AIDS: A Cross Sectional Study
... A depressive syndrome not fulfilling the ICD-10 or DSM- IV criteria for depressive episode may occur at any point in the course of HIV infection (WHO, 1988). Major depressive disorder has been reported in subjects ... See full document
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Enhanced in vitro human immunodeficiency virus type 1 replication in B cells expressing surface antibody to the TM Env protein.
... Human monoclonal antibodies to the human immunodeficiency virus type I HIV-1 transmembrane glycoprotein gp4l enhance HIV-1 infection in vitro.. Antibodies to the primary immunodominant d[r] ... See full document
9
DNA Microarrays for Virus Detection in Cases of Central Nervous System Infection
... Epstein-Barr virus (EBV; transformed B95a cell line), and VZV and echovirus (clinical isolates) were available from the virology laboratory of ...HSV-2, human herpesvirus 7 (HHV-7), HHV-6A, HHV-B, and ... See full document
8
Applications of the FIV Model to Study HIV Pathogenesis
... to the primary immunodominant domain of human immunodeficiency virus type 1 (hiv-1) 1010. glycoprotein gp41 enhance hiv-1 infection in vitro[r] ... See full document
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