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Profiling the serum protein corona of fibrillar human islet amyloid polypeptide

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Academic year: 2020

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Figure

Table 1B. Top 12 unique amyloid serum coronae (AE) proteins from the QCM method.
Figure 2. Sample nomenclature, replicates, methods and analytical pipeline implemented for bovine serum (FBS) only control (F) and amyloid plus FBS (AF) for CC preparations, as well centrifugal capture (CC) and quartz crystal micro-balance (QCM) amyloid-co
Figure 3. Overlap of protein identifications made using nLC-MS/MS analysis of centrifugal proteins and in plots (panels C/E: labels outside blue box, GRAVY ≤ -1.5 and ≥ 0.5, pI ≤ 4 and pI ≥ 10 | panel D: labels outside ranges GRAVY ≤ -1 and ≥ 0, pI ≤ 4.5 a
Figure 4. Quartz crystal microbalance (QCM) method amyloid and serum corona (AE) STRING48,49 (string-db.org) protein network (molecular action) produced using database and experimental interactors, with a minimum interaction score of 0.400 and no additiona
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