α helices
Investigation of hydrophobic moment and hydrophobicity properties for transmembrane α-helices
... of α -helical class to be less certain ...classify α -helices in cases where the hydrophobic moment for a particular amino acid sequence is greatly affected by the spatial arrangement of a few ...
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Protein structural analysis: α-helices and their interactions
... the contact area. Interactions with small central residues have packing angles around 90°. As the size of this central residue increases, the interhelix distance increases, the interhelical angle decreases and the range ...
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Visualization of α-Helices in a 6-Ångstrom Resolution Cryoelectron Microscopy Structure of Adenovirus Allows Refinement of Capsid Protein Assignments
... The 6-Å resolution reconstruction is significant in that ␣ -he- lices longer than 10 aa are now resolved within the icosahedral capsid. The backbone of a 10-residue ␣ -helix has nearly three complete helical turns, and ...
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Oligomerization of Hantavirus N Protein: C-Terminal α-Helices Interact To Form a Shared Hydrophobic Space
... Computer modeling of the C-terminal interaction region. The analysis of the probable domain architecture was done with SMART (16). Proteins having homologous sequences and partially similar secondary structures within ...
9
Modification of a loop sequence between α helices 6 and 7 of virus capsid (CA) protein in a human immunodeficiency virus type 1 (HIV 1) derivative that has simian immunodeficiency virus (SIVmac239) vifand CA α helices 4 and 5 loop improves replication in cynomolgus monkey cells
... In recent years, several host factors involved in HIV-1 restriction in OWM cells have been identified. ApoB mRNA editing catalytic subunit (APOBEC) 3 G modifies the minus strand viral DNA during reverse transcription, ...
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Hydrophobic α-Helices 1 and 2 of Herpes Simplex Virus gH Interact with Lipids, and Their Mimetic Peptides Enhance Virus Infection and Fusion
... Synthetic peptides mimicking ␣-H1 and ␣-H2 not only induce fusion of nude lipid vesicles but also enhance virus entry in a species-unspecific manner as well as cell-cell fusion.. MATERIA[r] ...
10
Stable single α-helices are constant force springs in proteins.
... 3 The abbreviations used are: SAH, single ␣-helix; AFM, atomic force microscopy; WLC, wormlike chain; p, persistence length; lc, contour length; P2P, peak-to-peak distance; Fu, unfolding[r] ...
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Insights into the infrared and Raman spectra of fresh and lyophilized royal jelly and protein degradation IR spectroscopy study during heating
... er in the fresh-solidified RJ and LRJ where the percentage of α-helices is higher. The strongest band at 1650–1660 cm –1 and much weaker absorp- tion around 1610 cm –1 originate from amide I modes ...
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An overview of the structures of protein DNA complexes
... tion helices of prokaryotic transcription factors (for example, those of the Cro and Repressor family, such as 1lli) are generally aligned with their axes parallel to base- pairing edges of the nucleotides, ...
37
Vol 68, No 2 (2016)
... connecting α-helices α4 and α5 containing residue H152, implying this loop region may play an important role in NTP substrate recog- nition, and the flexibility property of this loop may endow the ...
6
Statistical shape methodology for the analysis of helices
... Consider a helix in three-dimensional space along which a sequence of equally spaced points is observed, subject to statistical noise. For data coming from a single helix, a two-stage algorithm based on a profile ...
25
β-sheet containment by flanking prolines: Molecular Dynamic Simulations of the inhibition of β-sheet elongation by proline residues in human prion protein.
... There are fifteen proline residues in the human prion protein structure with twelve residues in the flexible N terminus. The twelve proline residues in the N terminus are periodic and conformationally stabilised by ...
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19. Position vectors of general helices in Euclidean 3-space
... nature. Helices arise in nano-springs, carbon nano-tubes, α-helices, DNA double and collagen triple helix, lipid bilayers, bacterial flagella in salmonella and escherichia coli, aerial hyphae in ...
8
Analysis of influenza A virus NS1 dimer interfaces in solution by pulse EPR distance measurements
... More speci fi cally, from the initial crystal structure of the ED, a dimer interface mediated by β -strand interactions was proposed (termed here the strand − strand dimer). 10 Subse- quent crystal structures of the ED ...
7
Restriction of HIV-1 by Rhesus TRIM5α Is Governed by Alpha Helices in the Linker2 Region
... TRIM5␣ proteins are a potent barrier to the cross-species transmission of retroviruses. TRIM5␣ proteins exhibit an ability to self-associate at many levels, ultimately leading to the formation of protein assemblies with ...
13
In Silico Modeling of the Rheological Properties of Covalently Cross-Linked Collagen Triple Helices
... triple helices, whose force-extension curves are well described by the wormlike chain (Kratky-Porod) model in which correlations in backbone orientation decay under thermal fluctuations over the persistence length ...
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Coupling H(+) transport to rotary catalysis in F type ATP synthases: structure and organization of the transmembrane rotary motor
... subunit b is estimated to extend 11 nm from the surface of the membrane (Rodgers and Capaldi, 1998). Subunit b is anchored in the membrane via a single transmembrane helix (TMH) at the N terminus, the structure of the ...
9
Dynamic ion pair behavior stabilizes single alpha helices in proteins.
... Simulations were performed using the CHARMM36 force field parameters with TIP3P water. The initial M7A SAH structure was built as a perfect α helix (internal dihedrals Φ = -57¡ and Ψ = -47¡). N-terminal Ser and ...
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Association of Protein Helices and Assembly of Foldamers: Stories in Membrane and Aqueous Environments
... There is a single aromatic tyrosine residue in each monomer of the homohexamer. Originally, the Tyr residue was included as a spectroscopic label, and positioned at the helix-helix interface of the Ala-Coil directed ...
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Regional Entrepreneurship and Innovation Management: Actors, Helices and Consensus Space
... Mapping of stakeholders and capabilities and providing value chain intelligence is an essential building stone in the implementation of a number of EU policies, a[r] ...
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