activation induced cell death (AICD)
Original Article CD4 T cell proliferation and inhibition of activation-induced cell death (AICD) in childhood asthma
... The inflammatory injury sites of asthma patients contain many activated lymphocytes, and the survival time of these lymphocytes is significantly prolonged [10]. Under normal con- ditions, the immune system can clear ...
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Bystander Sensitization to Activation-Induced Cell Death as a Mechanism of Virus-Induced Immune Suppression
... undergo AICD on receptor ...to AICD is transient, because the ability to respond to recall antigens returns after the acute phase of the antiviral immune response has ...CD44 activation/memory marker ...
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Lymphocyte Apoptosis during Classical Swine Fever: Implication of Activation-Induced Cell Death
... the situation results in aberrant stimulation of the T cells (42). Reduced mitogen responsiveness and increased susceptibility to apoptosis, both associated with the activated phenotype, have been reported for other ...
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Original Article Ubiquitin A20 maintains activation-induced CD4 T cell death
... The activation-induced cell death (AICD) indi- cates a condition that soon after activation, T cells become death ...of AICD is caused by the interaction of Fas ...
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Orphan nuclear receptor NR2F6 acts as an essential gatekeeper of Th17 CD4+ T cell effector functions
... receptor; AICD, activation induced cell death; AP-1, activating protein-1; Bcl6, B-cell lymph- oma 6 protein; BMAL1/ARNTL, aryl hydrocarbon receptor nuclear translocator-like; ...
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PubMedCentral-PMC4923328.pdf
... following activation of third-generation CAR T cells specific for ...Significant activation-induced cell death (AICD) of CAR T cells was observed after repeated antigen ...
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T cell apoptosis and reactive oxygen species
... of activation, division, and differentiation to generate a large pool of activated effector T ...apoptotic death to become memory T ...— activation- induced cell death ...
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Dynamics of Naive and Memory CD4+ T Lymphocytes in HIV 1 Disease Progression
... A cell that has become abortively infected is increased in its homing capability by upregu- lation of ...Any cell that becomes productively infected (whether memory or naive) must have been activated and ...
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A human immunodeficiency caused by mutations in the PIK3R1 gene
... B cell counts were low, and T cell blasts displayed enhanced activation-induced cell death, which was corrected by addition of the PI3Kd inhibitor ...to activation via the ...
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Pro- and anti-apoptotic CD95 signaling in T cells
... prototypic death receptor in and outside the immune ...apoptotic cell death. This activation-induced cell death was implicated in the control of immune cell ...
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Aged Garlic Extract Reduces ROS Production and Cell Death Induced by 6 Hydroxydopamine through Activation of the Nrf2 ARE Pathway in SH SY5Y Cells
... the activation mechanism of Nrf2-ARE pathway by AGE is mediated through some kinase sys- tems ...the activation of phosphati- dylinositol 3-kinase (PI3K)/Akt pathway is associated with the antioxidant ...
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Docosahexaenoic Acid Induces Cell Death through Downregulation of Hedgehog Signaling via Surt6 Activation in Human EGFR Mutant Non-Small Cell Lung Cancer
... SIRT6 activation downregulates Hh signaling to mediate DHA-induced cell death in human EGFR mutant NSCLC cells remains ...SIRT6 activation in PC9 ...
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Overexpression of selenoprotein H prevents mitochondrial dynamic imbalance induced by glutamate exposure
... excessive activation of glutamate ...in cell death both in vitro and in ...induces cell death by mechanisms that involve well defined, receptor-initiated excitotoxicity and non-receptor ...
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Amitriptyline induces mitophagy that precedes apoptosis in human HepG2 cells
... autophagic activation preceding apoptosis was involved in Amitriptyline- induced cell death, we examined both autophagic and apoptotic executive protein expression levels at 6, 12, 24, 48 and ...
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Glucagon-like peptides 1 and 2 and vasoactive intestinal peptide are neuroprotective on cultured and mast cell co-cultured rat myenteric neurons
... mast cell- induced neuronal cell ...Neuroprotection induced by GLP1 was reversed by either the addition of the GLP1 receptor antagonist, or the VIP receptor antago- ...on activation, or ...
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FK506 augments activation induced programmed cell death of T lymphocytes in vivo
... T cell receptor-mediated apoptosis ...apoptosis induced by in vivo anti-CD3 Ab ...was induced exclusively in antigen- stimulated T cells, since enhanced DNA fragmentation induced by in vivo ...
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Ginsenoside compound K induces apoptosis in nasopharyngeal carcinoma cells via activation of apoptosis-inducing factor
... of cell death induced by anti-cancer ...mainly induced by a caspase cascade or translocation of AIF ...caspase activation, which are the cell surface death receptor ...
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Activation of dynamin-related protein 1 - dependent mitochondria fragmentation and suppression of osteosarcoma by cryptotanshinone
... cancer cell growth. We supposed that CPT induced Drp1 activation caused the imbalance of fission and fusion impacting mitochondrial function which attributes to apoptotic signaling of can- cer ...
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Formulation and cytotoxicity evaluation of new self-emulsifying multiple W/O/W nanoemulsions
... P2X7 cell death receptor activation (YO-PRO-1 test), formulation A induced a concentration- dependent increase in fluorescence intensity when com- pared with the control cells after 1 hour and ...
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Pathogenesis and mechanisms of ethanol-induced limb defects
... limb cell death patterns to those of ethanol treated dams was ...Similarly, cell death was observed in the same region of the limb following exposure to each ...ethanol-induced ...
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