Anti-malarials
Fake anti malarials: start with the facts
... products circulating around the globe, a problem per- petuated as a result of increasing globalization. A number of countries lack technical capacity for conducting not just quality assurance, but more complex forensic ...
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Donor support for quality assurance and pharmacovigilance of anti malarials in malaria endemic countries
... While anti-malarials are generally considered safe and well tolerated, potential safety concerns warrant strength- ening their pharmacovigilance in malaria-endemic coun- ...of anti-malarial drugs in ...
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Private sector drug shops frequently dispense parenteral anti malarials in a rural region of Western Uganda
... received anti-malarials through the private sector actually had clinical ...parenteral anti-malarials were dispensed through private drug ...
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Susceptibility of human Plasmodium knowlesi infections to anti malarials
... From its natural simian hosts in Southeast Asia, Plasmo- dium knowlesi has emerged as a significant human pathogen, particularly in Malaysian Borneo [1-3]. Human P. knowlesi infections cause febrile illnesses that can ...
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Quality of anti malarials collected in the private and informal sectors in Guyana and Suriname
... of anti-malarials in the informal sector, the following approaches could be considered: 1) expand programmes, such as the active-case detection component of the “Looking for Gold Finding Malaria” programme ...
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A framework for assessing the risk of resistance for anti malarials in development
... of anti-malarials in the face of resistance is a critical question in the debate over malaria elimination and ...affordable anti-malarial Table 1 Resistance associated ...
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Saleability of anti malarials in private drug shops in Muheza, Tanzania: a baseline study in an era of assumed artemisinin combination therapy (ACT)
... Anti-malarials are within reach for most people living in town or visiting on twice weekly market days. Muheza is one of the 13 districts in Tanzania where the district hospital is a designated mission ...
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Access to artesunate amodiaquine, quinine and other anti malarials: policy and markets in Burundi
... of anti-malarials in public facilities were ...stocked anti-malarials 88%, 24%, and 97% stocked first-line treatment ACT, ...of anti-malarials in the ...
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Biological evaluation of hydroxynaphthoquinones as anti malarials
... older anti-malarials raises the need for the development of new drugs ...The anti-malarials currently used stem from six drug clas- ses: aminoquinolines, arylaminoalcohols, artemisinins, ...
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Natural anti–malarials: A bright hope
... Off course, the gravity of the situation has been compounded by the absence of a vaccine for protection. Further, plant compounds and its derivatives would only be a viable option for the treatment of drug resistant ...
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Assessment of the effectiveness of the CD3+ tool to detect counterfeit and substandard anti malarials
... authentic samples. Based on the high (70 %) NCW results reported by the study sites, even for the authentic samples, CePAT performed an investigation to determine if the use of CDAIL library images contributed to the ...
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Two successful decades of Swiss collaborations to develop new anti malarials
... The road to new products: new endoperoxides Although ACT has been the mainstay of public health policy over the last decade [1, 14], the early days of arte- misinin use were complicated by extreme price fluctua- tions, ...
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Atovaquone and quinine anti malarials inhibit ATP binding cassette transporter activity
... of anti- malarial compounds has not been explored in ...of anti-malarial compounds with ABC transport proteins could be drawn from different experimental set-ups ...of anti-malarial com- pounds with ...
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Were medicine quality and pharmaceutical management contributing factors in diminishing artemisinin efficacy in Guyana and Suriname?
... Although only mefloquine and quinine samples were identified that had no activity ingredient at all, several artemisinin derivative-containing medicines had content and/or dissolution problems. These type of failures ...
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Re imagining adherence to treatment from the “other side”: local interpretations of adverse anti malarial drug reactions in the Peruvian Amazon
... make anti-malarial campaigns pathogen and ...disease, anti-malarials are ‘weapons’, and experts (researchers, medical personnel) are the ‘fighters’, leaving aside peo- ple’s experiences and social ...
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Frequency and correlates of malaria over treatment in areas of differing malaria transmission: a cross sectional study in rural Western Kenya
... The proportion of children laboratory-confirmed negative malaria but were treated with anti-malarials was estimated and compared between sites using Chi- square test. The association between malaria over- ...
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Predictors of hyperlactataemia among children presenting with malaria in a low transmission area in The Gambia
... of anti-malarials, and weight percentile for age, derived with reference to Centers for Disease Control age- and sex-stratified growth charts [18]), respiratory symptoms (deep breathing, irregular ...
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Application of loop analysis for evaluation of malaria control interventions
... Intermittent preventive treatment (IPT) is also consid- ered a cause of spreading resistance. IPT is a method proposed to reduce malaria morbidity and mortality by providing regularly spaced therapeutic doses of ...
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Patterns of anti malarial drug treatment among pregnant women in Uganda
... Self-reported malaria was ascertained by asking the woman if she believed she was ever sick with malaria during the index pregnancy. If a study subject reported yes, then the timing and treatment of each presumed episode ...
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Improvements in access to malaria treatment in Tanzania after switch to artemisinin combination therapy and the introduction of accredited drug dispensing outlets a provider perspective
... of anti-malarials in public health facilities; and 3) retail audits to measure anti-malarial sales volumes in all public, mission and private ...of anti-malarial treatment doses dispensed ...
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