Antigen-presenting cells (APC)
The role of antigen presenting cells in the induction of HIV 1 latency in resting CD4+ T cells
... function-associated antigen (LFA)-1 can facilitate induction of latent infec- tion in the DC-T-cell model [14], while in other mod- els of in vitro latency CD2 expression, a molecule that binds to LFA-3, was ...
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An immunohistochemical study of CD83- and CD1a-positive dendritic cells in the decidua of women with recurrent spontaneous abortion
... potent antigen-presenting cells (APC) in the immune system with the unique ability to induce primary immune responses ...stem cells, migrate through the blood, and then disperse widely ...
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Management of hypersensivity pneumonitis
... APC: Antigen presenting cells; BALF: Broncho-alveolar lavage fluid; BFL: Bird- fancier lung; CTLA-4: Cytotoxic T-Lymphocyte Antigen 4; DCs: Dendritic cells; DLCO: Diffusing ...
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Direct, MHC dependent presentation of the drug sulfamethoxazole to human alphabeta T cell clones
... different antigen-presenting cells (APC) was measured both by proliferation and cytolytic as- ...matched APC. Fixation of APC was performed with glutar- aldehyde ...the ...
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Production Large Array of Cytokines by Mouse Dendritic Cells Pulsed with Hepatitis C Virus Pseudo-particles
... Dendritic cells (DC), the most potent antigen presenting cells (APC) found at trace levels in lymphoid and nonlymphoid tissues, are required for the priming of naive T ...dendritic ...
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Development of solid matrix antibody antigen (SMAA) complexes as multivalent subunit vaccines
... processing antigen for presentation to MHC class I- and class n-restricted T ...'non-replicating* antigen to the cytosol of appropriate antigen-presenting cells for the induction of MHC ...
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Genetically Transferred Central and Peripheral Immune Tolerance via Retroviral-Mediated Expression of Immunogenic Epitopes in Hematopoietic Progenitors or Peripheral B Lymphocytes
... Background: Based on the hypothesis that IgGs are potent tolerogens and that immature lymphohemato- poietic antigen-presenting cells (APC), and even mature peripheral B [r] ...
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The effects of cutaneous ultraviolet light exposure on migrating ovine dendritic cells
... ABBREVIATIONS AchE acetylcholine esterase antigen presenting cells APC ATPase adenosine triphosphatase BALT bronchus-associated lymphoid tissue benzo[a]pyrene BP cluster of differentiati[r] ...
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Naturally processed T cell epitopes from human glutamic acid decarboxylase identified using mice transgenic for the type 1 diabetes associated human MHC class II allele, DRB1*0401
... of antigen-specific immune modulation ...by antigen presenting cells (APC) resulted in the formation of DRB1*0401 complexes loaded with either the 274-286 or 115-127 epitopes, ...
8
In healthy primates, circulating autoreactive T cells mediate autoimmune disease
... Abbreviations used in this paper: APC, antigen-presenting cells; CNS, central nervous system; CSF, cerebrospinal fluid; EAE, experimental allergic encephalomyelitis; MBP, myelin basic pr[r] ...
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Inflammatory mechanisms in the lung
... injury; APC, antigen presenting cells; ARDS, Acute respiratory distress syndrome; BD, Bronchodilator; COPD, Chronic obstructive pulmonary disease; DC, Dendritic cell; DLCO, Diffusing capacity ...
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Validation of analytical methods in compliance with good manufacturing practice: a practical approach
... stem cells (BM MSCs) and Cytotoxic T Lymphocytes (CTLs), both cell therapy products that we will produce, in GMP conditions, for clinical trials of immunotherapy and regenerative medicine, and dendritic ...
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Gold specific T cells in rheumatoid arthritis patients treated with gold
... histocompatible antigen presenting cells as well as gold for induction of ...(EBV-B) cells and anti-HLA antibodies, the clones were shown to recognize gold in the context of DR1 ...active ...
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Specific tolerance to an acetylcholine receptor epitope induced in vitro in myasthenia gravis CD4+ lymphocytes by soluble major histocompatibility complex class II peptide complexes
... T cells have been cloned from MG patients, and in this study, we have induced long-lasting tolerance in vitro in one particular clone (PM-A1) with a known peptide epitope (alpha 144-163) and MHC class II ...
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Cancer immunotherapy by targeting immune checkpoints: mechanism of T cell dysfunction in cancer immunity and new therapeutic targets
... tumor cells and induce antitumor immun- ity, T cells are able to recognize tumor antigens pre- sented to T cell receptors (TCRs) by antigen-presenting cells ...T cells with its ...
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Enhanced presentation of MHC class Ia, Ib and class II restricted peptides encapsulated in biodegradable nanoparticles: a promising strategy for tumor immunotherapy
... involved antigen presenting cells must be able to “ cross present ” the exogenous peptides onto MHC class I molecules by either the classical proteasome and TAP-dependent pathway [42], or by an ...
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The role of the liver in the migration of parasites of global significance
... injection [44]. At day 21 p.i., a time at which self-cure usually has occurred, pigs did not show the typically observed decreased larval burden. This led the authors to believe that the liver played a crucial role in ...
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Induction of regulatory T cells: A role for probiotics and prebiotics to suppress autoimmunity.
... host cells are microbial-derived ligands of toll like receptors (TLRs) such as lipopolysaccharide (LPS) and flagellin, which activate, respectively, TLR-4 and -5 and modulate distinct aspects of host metabolism ...
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Novel regulatory therapies for prevention of Graft-versus-host disease
... T cells impairs stem cell engraftment, and delays immunologic reconstitution, rendering the recipient susceptible to post-transplant infections and disease relapse, with potentially lethal ...T cells and ...
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Adjuvants for peptide-based cancer vaccines
... immune cells such as DC, B cells and T cells as well as non-immune ...virus-infected cells, type I IFNs prevent virus replication by halting transcriptional and translational machineries, ...
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