antimalarial activities
Airlanggon A, a new isoprenylated benzoic acid fromthe roots of Erythrinasu bumbrans and their antioxidant and antimalarial activities
... and antimalarial activities from a new isoprenylated benzoic acid, airlanggon A (1) isolated from the roots of Erythrina subumbranstogether with known compounds, methyl 4,6- dihydroxy-2,5-dimethyl benzoic ...
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In vitro antioxidant and antimalarial activities of leaves, pods and bark extracts of Acacia nilotica (L ) Del
... All experiments were carried out in triplicates and results are expressed as mean values with standard deviation (± SD) of three replicates. One-way analysis of variance (ANOVA) and Tukey tests were carried out to ...
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Ni(II) complex of mefloquine pyrimethamine: Synthesis, toxicological and antimalarial activities against Plasmodium Berghei
... (ALP) activities of enzymes from the homogenates of liver, kidney and serum of the experimental ...rats. Antimalarial activities of the complex were investigated using mice infected with Plasmodium ...
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In vivo antimalarial activities of fractionated extracts of Asparagus africanus in mice infected with Plasmodium Berghei
... vivo antimalarial activity of chloroform, butanol and aqueous fractionates (100, 200 and 300 mg/kg) of Asparagus africanus roots against a chloroquine (CQ) sensitive strain of Plasmodium berghei ANKA was assessed ...
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In vivo antimalarial activities of russelia equisetiformis in plasmodium berghei infected mice
... Their activities were observed to be dose dependent and significantly higher amounts of the crude extracts were required to elicit such activities when compared to artesunate and chloroquine used as ...
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Characterisation of a novel bioactive complex polysaccharide from a marine invertebrate with potent anticancer and antimalarial activities
... Hepatocytes Growth Factor High-Performance Anion-Exchange Chromatography- pulsed amperometric High performance liquid chromatography Heparan sulphate Heparan Sulphate Heparan Sulphate Pr[r] ...
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ANTIPLASMODIAL ACTIVITY OF AGANOSMA CYMOSA
... for antimalarial activities in-vivo in rats inoculated with red blood cells parasitized with Plasmodium falcipuram using 4-day Suppressive test and Rane’s ...
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<i>In vitro</i> Antimalarial Activity of the Extracts of <i>Vernonia amygdalina</i> Commonly Used In Traditional Medicine In Nigeria.
... for antimalarial compounds has been necessitated by ...all antimalarial drugs. In this study, the in vitro antimalarial activities of the aqueous and ethanolic crude extracts of Vernonia ...
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Design, synthesis, conformational and molecular docking study of some novel acyl hydrazone based molecular hybrids as antimalarial and antimicrobial agents
... vitro antimalarial activities against chloroquine-sensitive malaria parasite Plasmodium falciparum (3D7) and antimicrobial activity against Gram positive bacteria ...
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Regioselective Synthesis and Biological Evaluation of 1 Hydroxyl Modified Ailanthinone Derivatives as Antimalarials
... vitro antimalarial activities with three available plasmodium strains: D6 (resistant to me- floquine but susceptible to chloroquine, quinine and pyrimethamine), W2 (resistant to chloroquine, quinine and ...
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Competing risk events in antimalarial drug trials in uncomplicated Plasmodium falciparum malaria: a WorldWide Antimalarial Resistance Network individual participant data meta analysis
... falling antimalarial efficacy (now observed for dihydroartemisinin–pipe- raquine in Cambodia and Vietnam [40–42]), simulation studies were conducted and reported elsewhere ...
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Antimalarial Activity of Otostegia integrefolia Leaf Extracts against Chloroquine Sensitive Strain of Plasmodium berghei in Mic
... of antimalarial drugs, the present study aimed at testing crude extracts from the leaves of Otostegia integrefolia against chloroquine (CQ) sensitive strain of Plasmodium berghei In vivo in Swiss albino ...potent ...
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Analysis of an ordinal outcome in a multicentric randomized controlled trial: application to a 3- arm anti- malarial drug trial in Cameroon
... Background: Malaria remains a burden in Sub-Saharan Countries. The strategy proposed by the World Health Organization (WHO) is to systematically compare the therapeutic efficacy of antimalarial drugs using as ...
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ANTIMICROBIAL AND ANTIMALARIAL EVALUATION OF SOME NOVEL 2,3 DIHYDRO 4 METHYL 2 THIOXO 1H IMIDAZOL 5 YL)ETHANONE
... antifungal activities, possibly acting through mechanism of actions, which are distinct from those of well-known classes of antimicrobial agents to which many clinically relevant pathogens are now ...
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Assessment of the efficacy of antimalarial drugs recommended by the National Malaria Control Programme in Madagascar: Up dated baseline data from randomized and multi site clinical trials
... The four main antimalarial drugs used and recommended by the NMCP were evaluated in five sites. In Tsiroano- mandidy, ASAQ was not evaluated because this drug was already assessed in another clinical trial [20] ...
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In Vitro Antimalarial, Antimicrobial and Antioxidants Activities of Salvia chudaei Batt & Trab (Lamiaceae) Extracts
... biological activities including anticholinesterase, antibacterial, antimalarial, anticancer also been reported to have a potent antioxidative effect ...
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Antimalarial metabolization: what have we learnt so far?
... effective metabolization and detoxification of drugs is key to therapeutic drug efficacy and this is carried out via two main reactions; Phase I and Phase II catalyzed by drug metabolizing enzyme. While Phase I reaction ...
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How antimalarial drug resistance affects post treatment prophylaxis
... lowing antimalarial treatment is inevitable. Antimalarial drug treatments with slowly eliminated drugs provide a variable period, after they have cleared the initial infec- tion, during which subsequent ...
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Antiplasmodial flavonoid from young twigs and leaves of Caesalpinia bonduc (Linn) Roxb
... anticancer, antimalarial, antihyperglycemic, anti-inflammatory, antirheumatic, anticonvulsant, anti- measles and antipyretic activities [8, 9, 10, ...
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Ethnobotanical perspective of antimalarial plants: traditional knowledge based study
... these antimalarial plants would assist people in identifying ecologically sensitive species and hence adoption of regeneration technique for that particular plant species, thus it supports health and economy of ...
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