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APC, antigen-presenting cells

Inflammatory mechanisms in the lung

Inflammatory mechanisms in the lung

... injury; APC, antigen presenting cells; ARDS, Acute respiratory distress syndrome; BD, Bronchodilator; COPD, Chronic obstructive pulmonary disease; DC, Dendritic cell; DLCO, Diffusing capacity ...

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Management of hypersensivity pneumonitis

Management of hypersensivity pneumonitis

... APC: Antigen presenting cells; BALF: Broncho-alveolar lavage fluid; BFL: Bird- fancier lung; CTLA-4: Cytotoxic T-Lymphocyte Antigen 4; DCs: Dendritic cells; DLCO: Diffusing ...

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In healthy primates, circulating autoreactive T cells mediate autoimmune disease

In healthy primates, circulating autoreactive T cells mediate autoimmune disease

... Abbreviations used in this paper: APC, antigen-presenting cells; CNS, central nervous system; CSF, cerebrospinal fluid; EAE, experimental allergic encephalomyelitis; MBP, myelin basic pr[r] ...

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The effects of cutaneous ultraviolet light exposure on migrating ovine dendritic cells

The effects of cutaneous ultraviolet light exposure on migrating ovine dendritic cells

... ABBREVIATIONS AchE acetylcholine esterase antigen presenting cells APC ATPase adenosine triphosphatase BALT bronchus-associated lymphoid tissue benzo[a]pyrene BP cluster of differentiati[r] ...

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Direct, MHC dependent presentation of the drug sulfamethoxazole to human alphabeta T cell clones

Direct, MHC dependent presentation of the drug sulfamethoxazole to human alphabeta T cell clones

... different antigen-presenting cells (APC) was measured both by proliferation and cytolytic ...matched APC. Fixation of APC was performed with glutaraldehyde ...

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The role of antigen presenting cells in the induction of HIV 1 latency in resting CD4+ T cells

The role of antigen presenting cells in the induction of HIV 1 latency in resting CD4+ T cells

... an antigen presenting cell (APC) subpopulation sequence, as labeled, n = ...non-inducing antigen presenting cell subpopula- tions using ...on antigen presenting cell ...

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An immunohistochemical study of CD83- and CD1a-positive dendritic cells in the decidua of women with recurrent spontaneous abortion

An immunohistochemical study of CD83- and CD1a-positive dendritic cells in the decidua of women with recurrent spontaneous abortion

... potent antigen-presenting cells (APC) in the immune system with the unique ability to induce primary immune responses ...stem cells, migrate through the blood, and then disperse widely ...

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Naturally processed T cell epitopes from human glutamic acid decarboxylase identified using mice transgenic for the type 1 diabetes associated human MHC class II allele, DRB1*0401

Naturally processed T cell epitopes from human glutamic acid decarboxylase identified using mice transgenic for the type 1 diabetes associated human MHC class II allele, DRB1*0401

... of antigen-specific immune modulation ...by antigen presenting cells (APC) resulted in the formation of DRB1*0401 complexes loaded with either the 274-286 or 115-127 epitopes, ...

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Development of solid matrix antibody antigen (SMAA) complexes as multivalent subunit vaccines

Development of solid matrix antibody antigen (SMAA) complexes as multivalent subunit vaccines

... processing antigen for presentation to MHC class I- and class n-restricted T ...'non-replicating* antigen to the cytosol of appropriate antigen-presenting cells for the induction of MHC ...

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Production Large Array of Cytokines by Mouse Dendritic Cells Pulsed with Hepatitis C Virus Pseudo-particles

Production Large Array of Cytokines by Mouse Dendritic Cells Pulsed with Hepatitis C Virus Pseudo-particles

... Dendritic cells (DC), the most potent antigen presenting cells (APC) found at trace levels in lymphoid and nonlymphoid tissues, are required for the priming of naive T ...dendritic ...

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Genetically Transferred Central and Peripheral Immune Tolerance via Retroviral-Mediated Expression of Immunogenic Epitopes in Hematopoietic Progenitors or Peripheral B Lymphocytes

Genetically Transferred Central and Peripheral Immune Tolerance via Retroviral-Mediated Expression of Immunogenic Epitopes in Hematopoietic Progenitors or Peripheral B Lymphocytes

... Background: Based on the hypothesis that IgGs are potent tolerogens and that immature lymphohemato- poietic antigen-presenting cells (APC), and even mature peripheral B [r] ...

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Novel regulatory therapies for prevention of Graft-versus-host disease

Novel regulatory therapies for prevention of Graft-versus-host disease

... T cells impairs stem cell engraftment, and delays immunologic reconstitution, rendering the recipient susceptible to post-transplant infections and disease relapse, with potentially lethal ...T cells and ...

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Phenotypic and functional abnormalities of bone marrow derived dendritic cells in systemic lupus erythematosus

Phenotypic and functional abnormalities of bone marrow derived dendritic cells in systemic lupus erythematosus

... To evaluate whether BM FLDCs comprise a subpopula- tion of pDCs and whether SLE BM FLDCs had higher pDC activity, we measured the level of IFN-α by using ELISA in the supernatants of BM FLDC and mDC cul- tures. IFN-α is ...

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Induction of regulatory T cells: A role for probiotics and prebiotics to suppress autoimmunity.

Induction of regulatory T cells: A role for probiotics and prebiotics to suppress autoimmunity.

... Other markers expressed by Treg include glucocorticoid-induced tumour necrosis factor receptor-related protein (GITR; also known as TNFRSF18, and CD357) and lymphocyte activation gene-3 (LAG-3) [29] and CD127 [30]. GITR ...

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Adjuvants for peptide-based cancer vaccines

Adjuvants for peptide-based cancer vaccines

... immune cells such as DC, B cells and T cells as well as non-immune ...virus-infected cells, type I IFNs prevent virus replication by halting transcriptional and translational machineries, ...

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Specific tolerance to an acetylcholine receptor epitope induced in vitro in myasthenia gravis CD4+ lymphocytes by soluble major histocompatibility complex class II peptide complexes

Specific tolerance to an acetylcholine receptor epitope induced in vitro in myasthenia gravis CD4+ lymphocytes by soluble major histocompatibility complex class II peptide complexes

... T cells have been cloned from MG patients, and in this study, we have induced long-lasting tolerance in vitro in one particular clone (PM-A1) with a known peptide epitope (alpha 144-163) and MHC class II ...

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How to fit allergen immunotherapy in the elderly

How to fit allergen immunotherapy in the elderly

... (NK) cells do not decrease in number, indeed their absolute number was found to increase in geriatric ...dritic cells play an important role, both in the innate and adaptive ...These cells have the ...

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Identification of naturally processed T cell epitopes from glutamic acid decarboxylase presented in the context of HLA DR alleles by T lymphocytes of recent onset IDDM patients

Identification of naturally processed T cell epitopes from glutamic acid decarboxylase presented in the context of HLA DR alleles by T lymphocytes of recent onset IDDM patients

... Investigation of the T cell response profile in an IDDM pa- tient expressing protective HLA-alleles. We next analyzed the Figure 3. Inhibition of peptide presentation by mAbs directed against MHC class I and class II ...

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Gold specific T cells in rheumatoid arthritis patients treated with gold

Gold specific T cells in rheumatoid arthritis patients treated with gold

... histocompatible antigen presenting cells as well as gold for induction of ...(EBV-B) cells and anti-HLA antibodies, the clones were shown to recognize gold in the context of DR1 ...active ...

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The era of bioengineering: how will this affect the next generation of cancer immunotherapy?

The era of bioengineering: how will this affect the next generation of cancer immunotherapy?

... and cells, especially in patients already compromised by the ...cancer cells upon apoptotic cell death, lead- ing to increased antigen uptake by dendritic cells (DCs) and immunization ...

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