Apoptotic genes
IMPACT OF CHRONIC UNPREDICTABLE STRESS ON THE EXPRESSION OF APOPTOTIC GENES IN ZEBRAFISH BRAIN
... The present study was designed to evaluate whether CUS lead to p53 induced apoptosis in zebrafish brain. The effects were studied from the expression of apoptotic genes like p53, noxa, bcl2 and caspase 3. ...
8
Evaluation of Apoptotic Genes Expression and Its Protein after Treatment of Cryptorchid Mice
... of apoptotic genes in a cryptorchid mouse model using a germ cell transplantation technique, established by injecting donor germ cells into seminiferous tubules of recipient mice ...the apoptotic ...
7
Mycoplasma synoviae induces upregulation of apoptotic genes, secretion of nitric oxide and appearance of an apoptotic phenotype in infected chicken chondrocytes
... transcription was increased in several pro-apoptotic genes. Twenty-four hours after infection, strong upregulation was assayed in NOS2, Mapk11, CASP8 and Casp3 genes. Twenty-four and 72 h incubation ...
14
Upregulation of the pro apoptotic genes BID and FAS in septic shock patients
... The apoptotic genes (BCL-2, the anti-apoptotic forms of BCL-XL, BAX, BAK, BIM, BID and FAS) and HLA-DRA PCR amplicons were obtained with the primer combinations presented in Table ...
10
Effects of Hydrogen Peroxide Oxidative Stress on the Pattern of Pro-apoptotic and Anti-apoptotic Genes Expression During PC12 Cells Differentiation
... study, apoptotic and anti-apoptotic genes were investigated, involved at the early stages of PC12 cells differentiation into neuron-like ...of genes in different stages of differentiation may ...
10
The polyphenol quercetin induces cell death in leukemia by targeting epigenetic regulators of pro-apoptotic genes
... A potential mechanism to induce apoptosis through his- tone deacetylase inhibitors (HDACi) is the upregulation of apoptotic genes. HADCi can activate components of the intrinsic pathway, including BAX and ...
11
Host Response to the Attenuated Poxvirus Vector NYVAC: Upregulation of Apoptotic Genes and NF-κB-Responsive Genes in Infected HeLa Cells
... Target verification and activation of representative cell pro- teins after NYVAC infection. Although changes in mRNA lev- els do not necessarily represent changes in protein expression, we used various approaches to ...
14
Original Article Apoptotic genes expression in placenta of clubfoot-like fetus pregnant rats
... Immunohistochemistry in ATRA-exposed group proved the same tendency on Bcl-2 and BAX compared to control group in tissue section. It has been shown that the pro-survival Bcl-2 blocks the release of cytochrome C from the ...
8
Differences in osteogenic and apoptotic genes between osteoporotic and osteoarthritic patients
... Regarding osteogenic activity, the macerated OP hip bone has repressed typical genes of osteoblast cell. So BGLAP (essential for bone mineralization), CDH11 (osteo- blast adhesion molecule) and Runx2 ...
8
Methanolic Extract from Aerial Parts of Artemisia Annua L. Induces Cytotoxicity and Enhances Vincristine-Induced Anticancer Effect in Pre-B Acute Lymphoblastic Leukemia Cells Artemisia Annua Extract Enhances Vincristine-Induced Cytotoxicity
... Our time- and concentration-dependent synergistic experiments revealed that metabolic activity was considerably hindered upon exposure of Reh cells to 0.1 nM VCR AAE in combination with 40 µg/ml AAE. We noticed a similar ...
8
Arsenic trioxide and ascorbic acid interfere with the BCL2 family genes in patients with myelodysplastic syndromes: an ex-vivo study
... WT1 genes was also ...housekeeping genes present in the card (18S, ACTB and ...pro-apoptotic genes, such as HRK, BAK1, CASPASE-5, BAD, TNFRSF1A, and BCL2L14 and down-regulation of ...disease, ...
8
Spatial, temporal and molecular hierarchies in the link between death, delamination and dorsal closure
... of apoptotic signals in driving cellular delamination in the amnioserosa and in patterning the spatiotemporal dynamics of ...pro-apoptotic genes and thus go beyond earlier observations (Toyama et ...
12
The CXCR4-CXCL12-Axis is of Prognostic Relevance in DLBCL and Its Antagonists Exert Pro-Apoptotic Effects in Vitro
... certain pro-apoptotic genes in CXCR4 positive lymphoma cell lines.. Finally, WK1 treatment.[r] ...
23
Effect of bone-marrow-derived mesenchymal stem cells on high-potential hepatocellular carcinoma in mouse models: an intervention study
... of apoptotic genes Bax and caspase 3 showed an obvious rising ...and apoptotic factors, and α -V and BSP factors, though it exhibited a significantly negative correlation with the expression of ...
9
Cerebral lactate metabolism and memory: Implications for Alzheimer's disease
... Gene expression profiles of transcripts in amyloid precursor protein transgenic mice: up-regulation of mitochondrial metabolism and apoptotic genes is an early cellular change in Alzhe[r] ...
229
Sp1 phosphorylation by ATM downregulates BER and promotes cell elimination in response to persistent DNA damage.
... in apoptotic fi- broblasts ...pro-apoptotic genes including BAX and PUMA (BBC3) in Sp1-depleted fibroblasts (Figure 6B and Supplementary Figure ...
13
Original Article Tanshinone IIA inhibits cell apoptosis in the compressed spinal cord by activating the PI3K/AKT signaling pathway
... many apoptotic genes is significantly ...above apoptotic gene expressions in the compressed spinal cord tissues of rats with spinal cord com- pression, the expressions of GSK-3β, Cyclin D1, and Bcl-2 ...
7
Viscum Album Modulates Apoptotic Related Genes in Melanoma Tumor of Mice
... apoptotis-related genes melanoma tumors in mice treated with Viscum album ...pro apoptotic genes (Trp53bp2, Nol3, Fadd, Tnfsf10, Traf1, Traf2, Cflar, Card10, Nod1, Casp 2, Casp7, Xiap, Dad1, and ...
10
Identification of candidate genes with pro-apoptotic properties by functional screening of randomly fragmented C DNA libraries
... pro-apoptotic genes using randomly fragmented cDNA libraries: the randomly fragmented cdna libraries were introduced into a375, Hs892-t, cls-354, HepG2, acHn and Mcf-7 cells by the nu- cleofector ...
7
HTLV 1 bZIP factor supports proliferation of adult T cell leukemia cells through suppression of C/EBPα signaling
... target genes which related with cell growth, but did not inhibit the C/EBPα- induced expression of anti-apoptotic genes including BCL2 and FLIP , suggesting that HBZ may fulfill its ...
13