Atherosclerosis and Inflammation
Relation between Malnutrition–Inflammation–Atherosclerosis (MIA complex) in Diabetic Patients with Peritoneal Dialysis
... DN is an important etiology of end stage kidney disease (ESRD). Inflammatory process plays an essential role in pathogenesis of DN. Inflammatory indicators such as serum albumin are higher in patients with diabetes and ...
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Canagliflozin attenuates the progression of atherosclerosis and inflammation process in APOE knockout mice
... attenuates atherosclerosis pro- cess in atherosclerotic mouse model through mechanisms that involve (1) improved glycemic control and decreased cholesterol and triglycerides, and (2) inflammation pro- cess ...
12
An accelerated mouse model for atherosclerosis and adipose tissue inflammation
... Here we show that in LDLR −/− mice addition of sucrose to a high-fat diet induces earlier and more pronounced adipose tissue inflammation, insulin resistance, glucose intolerance and atherosclerosis. As ...
12
Allergic lung inflammation promotes atherosclerosis in apolipoprotein E-deficient mice
... lesion inflammation, matrix degradation and media SMC loss, cell proliferation, apoptosis, and neovascularization after ALI production suggest the participation of these proteases in ALI-induced ...
22
Hyperhomocysteinemia enhances vascular inflammation and accelerates atherosclerosis in a murine model
... Lastly, recent studies in a murine model of geneti- cally mediated HHcy employing mice with heterozy- gous deletion of the gene encoding cystathionine-β- synthase (CBS) (52) revealed that HHcy was associated with both ...
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Regulations of the key mediators in inflammation and atherosclerosis by Aspirin in human macrophages
... There are evidences that components in the inflam- matory pathway, including cyclooxygenase-2 (COX-2) [7] and its product prostaglandin E2 (PGE2), contribute to the instability of atherosclerotic plaques. MMP-9 is also ...
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Extravascular inflammation in experimental atherosclerosis : the role of the liver and lungs
... for atherosclerosis in COPD ...systemic inflammation has a pathophysiological role in both COPD and atherosclerosis ...increased inflammation may be the missing link explaining the association ...
155
Nano-Antagonist Alleviates Inflammation and Allows for MRI of Atherosclerosis
... of inflammation remains a challenge in many pathologies, because of the necessary balance between host tolerance and efficacious inflammation ...of atherosclerosis, a chronic inflammatory condition ...
14
Transcription Factors in Response to Oxidative Stress: Implications for Atherosclerosis-Related Inflammation.
... It is well recognized that inflammation plays a crucial role in the initiation and progression of atherosclerosis. Many biological effects of reactive oxygen species and oxidized-low density lipoprotein ...
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Risk factors in coronary atherosclerosis athero-inflammation: the meeting point
... Many seroepidemiology studies suggest a relationship between infection and the pathophysiology of ischemic heart disease and the severity of atherosclerosis [126,127]. Chlamydia pneumoniae, cytomegalovirus and ...
11
Leukocyte RhoA exchange factor Arhgef1 mediates vascular inflammation and atherosclerosis
... decreases atherosclerosis in various experimental models (4–11), and clinical trials support this pro-atherosclerotic and proinflam- matory role of Ang II in humans (12, ...on inflammation and ...
12
The role of non resolving inflammation in atherosclerosis
... heightened inflammation owing to the release of inflammatory damage- associated molecular patterns (DAMPs) from the necrotic cells (4, ...lesional inflammation in chronic non-resolving inflammatory ...
12
Molecular Imaging of Inflammation in Atherosclerosis
... Acute rupture of vulnerable plaques frequently leads to myocardial infarction and stroke. Within the last decades, several cellular and molecular players have been identified that promote ather- osclerotic lesion ...
20
Probiotic mixture VSL#3 reduce high fat diet induced vascular inflammation and atherosclerosis in ApoE−/− mice
... of inflammation, as it reflected that the plaque vulnerabil- ity maybe ...another atherosclerosis devel- opment and thrombosis associated biomarker, tPAI-1, was significantly increased by telmisartan with ...
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Atherosclerosis and Alzheimer - diseases with a common cause? Inflammation, oxysterols, vasculature
... Brain scanning revealed that AD is associated with decreased cerebral blood flow [12,13], as also seen in AD mouse models [14]. Roher [15] examined cerebral arteries from confirmed AD cases and age-matched non-demented ...
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CD163+ macrophages promote angiogenesis and vascular permeability accompanied by inflammation in atherosclerosis
... The Atherosclerosis Risk in Communities (ARIC) study is a prospective, population-based cohort study designed to investigate the etiology and predictors of cardiovas- cular disease and has been described in detail ...
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Dynamic T cell–APC interactions sustain chronic inflammation in atherosclerosis
... which led to T cell proliferation and production of IFN-γ and TNF-α in the aorta. Since both T cell and APC numbers dramati- cally expand upon atherosclerosis progression, the number of their interactions may ...
14
Inflammation and atherosclerosis: The role of genetic polymorphisms in cardiovascular pathophysiology
... and atherosclerosis, a large number of studies have investigated the importance of genetic variants in the fibrinogen gene on this process (Appendix 1, Table ...
165
3-HMG-CoA Reductase Inhibitors and Inflammation: Underlying Mechanisms and Role in Atherosclerosis
... The inflammatory response, though intended to combat the plaque, actually renders it less stable and more prone to rupture, predisposing to increased risk of cerebrovascular accident and coronary heart disease. High ...
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Efficacy study of olmesartan medoxomil on coronary atherosclerosis progression and epicardial adipose tissue volume reduction in patients with coronary atherosclerosis detected by coronary computed tomography angiography: study protocol for a randomized controlled trial
... or inflammation, but the effects are weak and these treat- ments cannot achieve good results in patients with coron- ary atherosclerosis progression ...
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