B cell activation and function
B cell activation and Humoral Immunity
... the B cell receptor for B cell activation varies with the nature of the ...inducing B cell proliferation and ...major function of surface receptors is to bind and ...
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CFTR regulates B cell activation and lymphoid follicle development
... on B cell function and ac- tivation observed in murine analyses may be more pro- nounced or altered in human ...−/− B cells to promote humoral immunity and host defense as it was beyond the ...
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Effects of in vitro corticosteroids on B cell activation, proliferation, and differentiation
... on B cells and/or modulation of accessory cell ...the B cell cycle such as the proliferative response to B cell growth factor after either in vivo or in vitro activation ...
9
T cell–independent B cell activation induces immunosuppressive sialylated IgG antibodies
... T cell–dependent (TD) protein antigens and proinflammatory ...T cell–independent (TI) B cell activation via B cell receptor (BCR) crosslinking through polysaccharides or ...
10
Mechanisms of anti-Sm B cell activation in autoimmune Fas-deficient mice
... long-lived B cell ...Sm B cells are activated in disease, as we hypothesize the Fas lpr DCs are contributing to the induction of chronic, long-lived B cell ...MZ B cell ...
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Hormonal milieu at time of B cell activation controls duration of autoantibody response
... DNA-reactive B cell can mature as either MZ or Fo cells depending on hormonal ...on B cell function, independent of the numerous immune perturbations that are present in spontaneous ...
22
CVID associated TACI mutations affect autoreactive B cell selection and activation
... naive B cell compartments compared with CVID patients with a single TACI ...autoreactive B cells is accompanied by profound impairments of B cell activation after BCR, TLR7, and ...
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Cell Volume Regulation in Immune Cell Function, Activation and Survival
... platelet function caused by improper volume regulation can lead to blood clotting and thus have damaging effects such as myocardial infarction, stroke, or pulmonary embolism ...proper function, platelets ...
18
Calcium sensing receptor activation increases cell cell adhesion and ß cell function
... Methods: Immunocytochemistry and western blotting confirmed the expression of CaR in MIN6 β- cell line. The calcimimetic R568 (1μM) was used to increase the affinity of the CaR and specifically activate the ...
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Estrogen alters thresholds for B cell apoptosis and activation
... zone B cells or, alternatively, that their antigenic specificity determines their local- ization to the marginal zone compartment ...naive B cell repertoire by estrogen by identifying alterations in ...
10
The role of Rac GTPases in B cell development and activation
... and activation of B cells is dependent upon signals transduced downstream of the ...the function of the haematopoietic-specific isoform Rac2 in B cell development and activation ...
241
Activation of FXR pathway does not alter glial cell function
... FXR activation or supernatant of FXR-activated ...f). Activation of FXR cultures using 10 and 20 μ M GW4064 during 14 days of remyelination in cerebellar slice after toxic demyelination does not alter the ...
10
Characterization of B Cell Development and Activation in the Absence of Akt or Presenilin
... to B cell biology, B1 and MZ B cells with their “innate-like” T- cell independent functions may serve as the foundation of the humoral immune ...FOL B cells ...may function in a ...
133
Loss of Gαq impairs regulatory B cell function
... the activation of STAT3 and ERK ...Gαq. Activation of the ERK pathway is a common require- ment for IL-10 expression by T cells, macrophages, and myeloid dendritic cells ...p38 activation after TLR ...
13
Effects of Ebola Virus Glycoproteins on Endothelial Cell Activation and Barrier Function
... endothelial cell destruction, the role of the soluble glycoproteins in pathogenesis is largely unknown; however, they are hypothesized to be of biological relevance in terms of target cell activation ...
9
T90/44 (9.3 antigen). A cell surface molecule with a function in human T cell activation.
... T90/44 IS a cell surface antigen which IS present on human Τ cells of the helper and cytotoxic subsets and which binds the 9 3 monoclonal antibody (9 3'mAb) It is expressed in the form o[r] ...
8
Chronic activation of a designer Gq coupled receptor improves β cell function
... β cell function are predicted to prove beneficial for the treat- ment of ...selective activation of β cell G q signaling greatly improve β cell function and glucose homeostasis ...
14
Activation of the P2Y2 receptor regulates bone cell function by enhancing ATP release
... TITLE: Activation of the P2Y2 receptor regulates bone cell function by enhancing ATP release AUTHORS: Isabel R Orriss, Dilek Gueneri, Mark Or Hajjawi, Kristy Shaw, Jessal J Patel, and Tim R ...
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The E26 Transformation-Specific Transcription Factors PU.1, Spi-B, and Spi-C Regulate Transcriptional Activation and Repression of Nfkb1 to Control B Cell Development and Function
... PUB B cells. PUB B cells were unable to increase MHCII or CD40 expression upon LPS or anti-IgM ...PUB B cells. CD40 was functional in PUB B cells since anti-CD40 stimulation appeared normal ...
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CD4 T cell activation by B cells in human Leishmania (Viannia)infection
... T cell activation by T cells are antigen presentation and cytokine ...Since B cells stimulated with pLAg did not produce any significant amount of 13 cytokines that are prominent in antigen induced ...
13