B cell subsets
Evidence of Early B-Cell Dysregulation in Simian Immunodeficiency Virus Infection: Rapid Depletion of Naïve and Memory B-Cell Subsets with Delayed Reconstitution of the Naïve B-Cell Population
... total B (CD20 ⫹ ) cells in the periphery decreases dramatically during the acute phase of infection (13, ...total B cells is greater in magnitude than the loss of CD4 ⫹ T cells ...characterize ...
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B cell subsets and dysfunction of regulatory B cells in IgG4 related diseases and primary Sjögren’s syndrome: the similarities and differences
... and B-cell activation, wherein the CD40-CD40L and CD28- CD80/CD86 pathways are well known to cross-talk be- tween T and B ...in B-cell differentiation and activation ...T ...
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Alterations on peripheral B cell subsets following an acute uncomplicated clinical malaria infection in children
... orchestrate B lymphocyte depletion are unknown, ...with B cell lymphopoiesis, induce lym- phocyte apoptosis as shown following infection of macaques with ...memory B cells, is driving memory ...
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B cell profiling in malaria reveals expansion and remodeling of CD11c+ B cell subsets
... Flow cytometry. Frozen PBMCs were thawed in a 37°C water bath and mixed with 1 equal volume cold Iscove’s Modified Dulbecco’s Medium supplemented with L-glutamine (2 mM), penicillin (100 U/ml), streptomycin (100 μg/ml), ...
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Alteration of B-Cell Subsets Enhances Neuroinvasion in Mouse Scrapie Infection
... The conclusion reached in this study that closeness of the FDC network and the peripheral nervous system in CD19 ⫺/⫺ mice may allow a more efficient migration of prions between the two sites is supported by a recent ...
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Micro-scale flow cytometry-based and biochemical analysis of lipid signaling in primary B cell subpopulations
... 10 N HCl and chilling cells on ice. Soluble IPs were extracted by adding 465 μl of chloroform/methanol (1:2 v/v). The mixture was vortexed for 2 minutes at maximum speed, followed by addition of 156 μl each of chloroform ...
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B lymphocyte typing for prediction of clinical response to rituximab
... memory B cells are reduced in our RA cohort, this subset is significantly enriched in CD95 + cells in non-responders (Figure ...pre-switch B-cell population is enriched in autoantibody-producing ...
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Prognostic value of B cells in cutaneous melanoma
... of B cell popula- tions within melanoma tumors and associate this with B cell functional phenotypes and B cell receptor repertoire ...significant B cell ...
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Race-related differences in antibody responses to the inactivated influenza vaccine are linked to distinct pre-vaccination gene expression profiles in blood
... specific B cells by reducing the antigenic load ...naïve B cells and lower expression of co-inhibitors on B cell subsets in younger African Americans or the very pronounced differences ...
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Identification of Hodgkin and Reed Sternberg cell specific genes by gene expression profiling
... center B cells (or rarely, T cells) but have a hetero- geneous and largely uncharacterized ...HL cell lines with profiles of the main B cell subsets and B cell non-HLs to ...
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Abnormal B cell memory subsets dominate HIV specific responses in infected individuals
... memory B cells were identified using 3 trimeric HIV envelope gp140 probes: gp140-WT; a mutant gp140 probe with a single-point muta- tion in the CD4 binding region (D368R); and a mutant gp140 probe with a ...
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Increased serum concentrations of IL 1 beta, IL 21 and Th17 cells in overweight patients with rheumatoid arthritis
... T cell and B cell subsets and monocytes were compared between the three BMI groups among healthy donors and patients with RA (Table ...immune cell frequencies in the three BMI groups ...
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Circulating plasmablasts/plasma cells: a potential biomarker for IgG4 related disease
... Different B-cell populations were stained with phycoerythrin (PE)-cyanine 7 (Cy7)- anti-CD19, fluorescein isothiocyanate-anti-CD24, allophycocyanin-anti-CD38, peridinin chlorophyll ...PE-anti- ...
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Disseminated cytomegalovirus disease after bendamustine: a case report and analysis of circulating B and T cell subsets
... a B-cell lymphoma characterized by an infiltrate of heterogeneous B-cells and IgM hypersecre- tion ...remaining B-cell subsets. We investigated the B-cell immune ...
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Good syndrome presenting with CD8+ T-Cell large granular lymphocyte leukemia
... granzyme B; the expression of CD107a, a marker for degranulation of cytotoxic granules following cellular activation, and perforin expression was comparable to ...Granzyme B can be seen in the bone marrow ...
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Studies of immune functions of patients with systemic lupus erythematosus T cell subsets and antibodies to T cell subsets
... effective in eliminating suppressor function only when T cells were treated before activation; there was no effect when treatment was performed after activation. These studies indicate that the antibodies preferentially ...
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Dynamic analysis of lymphocyte subsets of peripheral blood in patients with acute self limited hepatitis B
... Hepatitis B virus (HBV), complex immune responses could be caused, and cell-mediated immunity is an important factor to determine results of HBV infection ...Different subsets of lymphocyte have ...
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A comparison between protein profiles of B cell subpopulations and mantle cell lymphoma cells
... of B cell populations from healthy individuals The normal B cell populations were extracted from fresh tonsils obtained from patients undergoing tonsillecto- mies at the surgical department, ...
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Immunoregulatory T Cell Function in Multiple Myeloma
... monoclonal B cell differentiation and immunoglobulin ...mitogen-induced B cell differentiation assays, proliferation and polyclonal immunoglobulin secretion optimally requires T cell ...
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A splenic IgM memory subset with antibacterial specificities is sustained from persistent mucosal responses
... ysis, cell suspensions of spleen, PPs, lymph nodes, and other tissues were incubated on ice for 20 min with combinations of fluorochrome-conjugated antibodies in PBS supplemented with ...
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