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Biological interaction networks associated with differentially

Extraction of biological interaction networks from scientific literature

Extraction of biological interaction networks from scientific literature

... performances, advantages and drawbacks: while syntax-based approaches need no further domain-specific information, they can easily be applied in different domains, but suffer from a lower precision than semantic parsers. ...

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Evolution of biological interaction networks: from models to real data

Evolution of biological interaction networks: from models to real data

... each biological net- work is likely to be underestimated due to the inability to observe multiple rewiring events since the last common ancestor, such a method is capable of elucidat ing the network ...regulatory ...

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Cancerin: A Computational Pipeline to Infer Cancer-Associated ceRNA Interaction Networks

Cancerin: A Computational Pipeline to Infer Cancer-Associated ceRNA Interaction Networks

... miRNA-mediated interaction between RNAs—called competing endogenous RNA (ceRNA) interaction—can play important roles in ...cancer- associated ceRNA ...ceRNA networks were involved in ...

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Modeling multi-valued biological interaction networks using Fuzzy Answer Set Programming

Modeling multi-valued biological interaction networks using Fuzzy Answer Set Programming

... synthetic networks Due to the limited availability of results about them in the literature, experiments on real biological networks can only paint a small picture on the efficiency of the application ...

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Identification of Differentially Activated Cell-Signaling Networks Associated with Pichinde Virus Pathogenesis by Using Systems Kinomics

Identification of Differentially Activated Cell-Signaling Networks Associated with Pichinde Virus Pathogenesis by Using Systems Kinomics

... these differentially involved networks, we have identified a number of key signaling “nodes” which show differential phosphorylations between mild and lethal ...

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Microarray Analysis of Differentially Expressed
LncRNAs with Associated Co-Expression and CeRNA
Networks in Coronary Heart Disease

Microarray Analysis of Differentially Expressed LncRNAs with Associated Co-Expression and CeRNA Networks in Coronary Heart Disease

... LncRNA HIT000066433 can regulate mRNA expression through Nkx2-5 TF. Therefore, we hypothesized that these TFs can play vital roles in the occurrence and development of CHD through regulating the expression of lncRNAs and ...

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Mining Biological Networks

Mining Biological Networks

... genes associated with phenotipic ...of differentially expressed genes or ...of differentially expressed genes fails to provide mechanistic insights into the underlying biology of the condition being ...

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Mining of vaccine-associated IFN-γ gene interaction networks using the Vaccine Ontology

Mining of vaccine-associated IFN-γ gene interaction networks using the Vaccine Ontology

... The networks of gene-vaccine and vaccine-vaccine associations An abstract-level co-occurrence method was used to identify the specific vaccines that are associated with IFNG and the top ranked 32 genes ...

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Ontology-based literature mining of E. coli vaccine-associated gene interaction networks

Ontology-based literature mining of E. coli vaccine-associated gene interaction networks

... For rational pathogenic E. coli vaccine design, it is critical to understand E. coli gene functions and E. coli- host interaction mechanisms. With over 35,000 E. coli- related articles published in PubMed, it is ...

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Module Identification for Biological Networks

Module Identification for Biological Networks

... There are many algorithms developed to identify functional modules with the consideration of interaction patterns. For example, Power Graph (PG) [86] greed- ily collects topological similar nodes into the same ...

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Exploring modularity in biological networks

Exploring modularity in biological networks

... of biological modularity fall under the umbrella of exploratory ...protein-protein interaction, gene regulatory networks) to be conceptualized as groups of tightly connected nodes? Must ...

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Translin and Trax differentially regulate telomere-associated transcript homeostasis

Translin and Trax differentially regulate telomere-associated transcript homeostasis

... the interaction sites of the Schizosaccharomyces pombe protein Tranlisn with nucleic acids and proteins: a combined molecular genetics and bioinformatics ...

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A genetic risk score is differentially associated with migraine with and without aura.

A genetic risk score is differentially associated with migraine with and without aura.

... significantly associated with MWA, further studies characterized by larger sample size and powered enough to identify rare genetic variants could be of help to construct a GRS that could prove to be more spe- ...

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Identification of fever and vaccine-associated gene interaction networks using ontology-based literature mining

Identification of fever and vaccine-associated gene interaction networks using ontology-based literature mining

... Vaccines (including 4 specific vaccine names) were found to directly interact with 26 genes. Gene set enrichment analysis was performed using the genes in the generated interaction networks. Moreover, the ...

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Identification of fever and vaccine-associated gene interaction networks using ontology-based literature mining

Identification of fever and vaccine-associated gene interaction networks using ontology-based literature mining

... Vaccines (including 4 specific vaccine names) were found to directly interact with 26 genes. Gene set enrichment analysis was performed using the genes in the generated interaction networks. Moreover, the ...

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Biological relevance of spiking neural networks

Biological relevance of spiking neural networks

... In chapter 4, we propose a biologically inspired application of the the LIF net- work model coupled with inhibitory synapses to simulate the dynamics of MSNs in the striatum. Striatal projection neurons form a ...

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Osteopontin Splice Variants Differentially Exert Clinicopathological Features and Biological Functions in Gastric Cancer

Osteopontin Splice Variants Differentially Exert Clinicopathological Features and Biological Functions in Gastric Cancer

... In GC tissues, increased expression of OPN-b or OPN-c, but not of OPN-a, was associated with diverse clinicopathological features. In according with our observation, it has been reported that high OPN-b or OPN-c ...

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Brain activations to emotional pictures are differentially associated with valence and arousal ratings

Brain activations to emotional pictures are differentially associated with valence and arousal ratings

... The present findings were realized on the basis of several task characteristics, which might be considered for future studies. First, our results indicate that inter-individual differences in rating of valence and ...

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Environmental Sources of Bacteria Differentially Influence Host-Associated Microbial Dynamics

Environmental Sources of Bacteria Differentially Influence Host-Associated Microbial Dynamics

... of interaction between the environment and the host microbiome to understand whether this interaction corre- lated with the perceived stability of the microbial community of each ...

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Identification of active disease-associated subnetworks in human protein-protein interaction networks using the MCL algorithm

Identification of active disease-associated subnetworks in human protein-protein interaction networks using the MCL algorithm

... be associated with RA via its relation to ECM with the action of transforming-growth-factor (TGF)-β following inflammatory responses is being characterized by increased production of extracellular matrix (ECM) ...

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