Bone marrow-derived mesenchymal stem cell
Role of geometrical cues in bone marrow derived mesenchymal stem cell survival, growth and osteogenic differentiation
... affecting cell attachment (34,35) migration (36–38), growth (39–44) and differentiation ...support cell growth, convex or flat surfaces in same 3D system can inhibit it ...of cell growth and ...
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Mesenchymal stem cells: potential application for the treatment of hepatic cirrhosis
... Adipose-derived mesenchymal stem cell; ALD: Alcoholic liver disease; BM-MSC: Bone marrow-derived mesenchymal stem cell; CB-MSC: Cord blood- ...
7
Adipose Tissue and Bone Marrow-Derived Mesenchymal Stem Cells Role in Regeneration of Cleft Alveolus in Dogs
... All surgical procedures were conducted after three weeks from the initial stem cell surgery. The second surgery was done under aseptic condition and GA. The surgical site was shaved, washed with water and ...
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Effect of bone marrow-derived mesenchymal stem cells and stem cell supernatant on equine corneal wound healing in vitro
... crease cell proliferation and chemotactic migration [39, 40], and PDGF-BB increases matrix production and chemo- taxis and enhances inflammatory reactions to accelerate tissue repair [38, ...
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Comparative analysis of curative effect of bone marrow mesenchymal stem cell and bone marrow mononuclear cell transplantation for spastic cerebral palsy
... of cell tech- nology, a number of clinical studies have shown that stem cell transplantation in the treatment of traumatic brain injury [12], cerebral haemorrhage [15], stroke [16], spi- nal cord ...
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An improvised one-step sucrose cushion ultracentrifugation method for exosome isolation from culture supernatants of mesenchymal stem cells
... Mesenchymal stem cells (MSCs) are multi-potent self- renewing cells having remarkable potential in regenerative ...are derived from various sources like bone marrow (BMSCs), dental ...
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A novel and generalizable organotypic slice platform to evaluate stem cell potential for targeting pediatric brain tumors
... needed. Stem cells may provide the basis for a new approach. Emerging stem cell therapy of brain tumors The lack of efficacy for conventional treatments of malig- nant brain tumors can be readily ...
11
Mesenchymal stem cell-based therapy in kidney transplantation
... fat, bone, cartilage, umbilical cord, cord blood, synovium, synovial fluid, muscle, skin and ...the bone marrow microenvironment, which promotes the function of hematopoietic stem cells ...
7
Human bone marrow mesenchymal stem cell-derived exosomes stimulate cutaneous wound healing mediates through TGF-β/Smad signaling pathway
... Human bone marrow-derived mesenchymal stem cells; hBM- MSC-Ex: Human bone marrow mesenchymal stem cell-derived exosomes; ALP: Alkaline ...
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Role of Bone Marrow-Derived Mesenchymal Stem Cells Differentiate into β Cells in the Pancreatic Microenvironment
... of stem cells is controlled by their intrinsic genetic program and surrounding microenvironment, which determines the fate of adult stem cells ...β- cell; (2) the micro-environment for normal ...
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Exosomes from bone marrow mesenchymal stem cells enhance fracture healing through the promotion of osteogenesis and angiogenesis in a rat model of nonunion
... from bone tissues around the fracture site was extracted from the control group, CM-Exo group and Exo group 20 weeks after the ...operation. Bone tissues were derived from the animals and ground into ...
15
Original Article Comparison of different conditions for culturing of mesenchymal stem cells from human umbilical cord Wharton’s jelly
... Mesenchymal stem cells (MSCs) are undiffer- entiated cells that can self-renew and provide high proliferative ...various cell types, including chondro- cytes, osteocytes, adipocytes, myocytes, and ...
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The challenges and promises of allogeneic mesenchymal stem cells for use as a cell-based therapy
... The effectiveness of genetically modified auto-MSCs has been reported in different disease models [50–52]. Similarly, the protective effect of allo-MSCs was im- proved by gene modification. de la Garza-Rodea et al. [53] ...
7
Stem cell technology for bone regeneration: current status and potential applications
... In a clinical setting, however, the therapeutic use of MSC is hindered by several drawbacks that include the low yield of BMSC procurement, the use of growth factors and extensive in vitro culture for their expansion to ...
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The therapeutic impact of human neonatal BMSC in a right ventricular pressure overload model in mice
... of bone marrow was obtained from children with various CHDs who were receiving recon- structive heart ...human marrow sample was con- ducted in accordance with a previously reported proto- col ...the ...
11
Promising advances in clinical trials of dental tissue-derived cell-based regenerative medicine
... tissue- derived cell-based regenerative medicine could provide insights into emerging potential expansion and novel therapeutic approaches to induce endogenous modula- tion ...
10
Therapeutic prospects of extracellular vesicles in cancer treatment
... EVs derived from native or primed/genetically modified cells can be used in antitumor ...programmed cell death 6 interacting protein (PDCD6IP), tumor susceptibility gene 101 protein (TSG101), and flotillin ...
10
VEGF with AMD3100 Endogenously Mobilizes Mesenchymal Stem Cells and Improves Fracture Healing
... mesenchymal stem cells derived from bone marrow or peripheral blood of rats.J. 551[r] ...
32
Boosting tendon repair: interplay of cells, growth factors and scaffold-free and gel-based carriers
... large surface and biocompatibility. The current materials used in tendon tissue engineering have provided signifi- cant advances in structural integrity and biological com- patibility and in many cases the results are ...
13
Preclinical Study of Lung Spheroid Cell Therapy in Rodent Models of Pulmonary Fibrosis.
... into stem cells in vivo ...epithelial cell survival (Fig. 3C) and endothelial cell tube formation ...and cell apoptosis ...injected stem cells regenerate damaged tissues through ...
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