Bone Marrow-Derived MSC
Intrathecal Autologous Bone Marrow Derived MSC Therapy in Cerebral Palsy: Safety and Short Term Efficacy
... autologous MSC therapy in cases of ...underwent bone marrow aspiration and MSC ...Autologous MSC injection in CP patients showed short-term safety, with variable efficacy in improving ...
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Protein synthesis and secretion in human mesenchymal cells derived from bone marrow, adipose tissue and Wharton’s jelly
... tissue-derived MSC; bFGF: Basic fibroblast growth factor; BM-MSC: Bone marrow-derived MSC; DMEM: Dulbecco ’ s modified Eagle media; EGF: Endothelial growth factor; FBS: ...
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Bone marrow contribution to synovial hyperplasia following joint surface injury
... of bone marrow-derived MSCs into organs and tissues has been reported to occur in intestine and muscle [26], and also in skin ...of bone marrow-derived MSCs to synovium are ...
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Transcriptional profiling reveals intrinsic mRNA alterations in multipotent mesenchymal stromal cells isolated from bone marrow of newly-diagnosed type 1 diabetes patients
... C-MSC, bone marrow-derived MSC isolated from healthy donors (controls); CKLF, chemokine-like factor; COX2, cyclooxygenase-2; CXCL12, (C-X-C motif) ligand 12 chemokine; DAVID, Database ...
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Human bone marrow mesenchymal stem cell-derived exosomes stimulate cutaneous wound healing mediates through TGF-β/Smad signaling pathway
... TGF-β/Smad signal pathway is an evolutionarily con- served pathway with numerous functions ascribed [9]. Transforming growth factor-beta (TGF-β) is considered as one of the essential growth factors in the natural wound ...
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Effects of intravenous administration of allogenic bone marrow- and adipose tissue-derived mesenchymal stem cells on functional recovery and brain repair markers in experimental ischemic stroke
... by MSC may affect synaptogenesis in the ischemic brain ...BM- MSC and AD-MSC administration in comparison with the infarct ...i.v. MSC administration [42] and we detected in our study that it ...
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Mesenchymal stem cells: potential application for the treatment of hepatic cirrhosis
... BM-MSC: Bone marrow-derived mesenchymal stem cell; CB-MSC: Cord blood- derived mesenchymal stem cell; c-met: Cellular mesenchymal to epithelial transition factor; CXCR4: ...
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Tissue source determines the differentiation potentials of mesenchymal stem cells: a comparative study of human mesenchymal stem cells from bone marrow and adipose tissue
... isolated bone marrow and adipose-derived MSCs from people aged older than 60 ...from bone marrow were better for bone ...ing MSC differentiation may be a predictive ...
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Rühland, Svenja (2019): 3D imaging and analysis of mesenchymal stem cells and cytotoxic T lymphocytes invading tumor spheroids. Dissertation, LMU München: Medizinische Fakultät
... apceth-derived MSC batches (AP), and five MSC isolates established in our laboratory ...were bone marrow-derived, and were in passage ...and MSC 110501M) and one umbilical ...
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Heterogeneity of proangiogenic features in mesenchymal stem cells derived from bone marrow, adipose tissue, umbilical cord, and placenta
... Previous studies have shown that the endothelial differen- tiation mechanism participates in MSC-mediated wound healing [19]. To investigate their capabilities of endothelial differentiation, BMSCs, AMSCs, UMSCs, ...
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Bovine fetal mesenchymal stem cells exert antiproliferative effect against mastitis causing pathogen Staphylococcus aureus
... from MSC derived from fetal bovine bone marrow (BM-MSC) and adipose tissue ...bovine MSC may be mediated by bBD4A and NK1 ...
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Extracellular vesicles derived from mesenchymal stromal cells: a therapeutic option in respiratory diseases?
... in MSC-derived EVs are usually related to development, cell survival, and differenti- ation, while some MSC-derived EVs-enriched miRNAs are more closely associated with regulation of the ...
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Percutaneous Intramyocardial Delivery of Mesenchymal Stem Cells Induces Superior Improvement in Regional Left Ventricular Function Compared with Bone Marrow Mononuclear Cells in Porcine Myocardial Infarcted Heart
... types, bone marrow-derived mononuclear cells (BMMNC) have been most widely applied in clinical trials and basic research ...[2-7]. Bone marrow-derived mesenchymal stem cells ...
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Role of whole bone marrow, whole bone marrow cultured cells, and mesenchymal stem cells in chronic wound healing
... of bone marrow cells gave an impelling reason to study the role of bone marrow in chronic wound healing and several clinical studies have reported on its benefit ...whole bone ...
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Pharmacological targeting of bone marrow mesenchymal stromal/stem cells for the treatment of hematological disorders
... There are two types of multipotent cells in bone mar- row (BM): hematopoietic stem/progenitor cells (HSCs) and mesenchymal stromal/stem cells (MSCs). HSCs produce all types of hematopoietic cells and are estab- ...
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Secreted trophic factors of mesenchymal stem cells support neurovascular and musculoskeletal therapies
... of MSC trophic activities ...nascent bone formation [59, 60]. Recent work also suggests that AD-MSC, BM-MSC, and dental pulp stem cell-secreted CXCL14 and CCL2 help to recruit CXCR4 + cells ...
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Human ES-derived MSCs correct TNF-α-mediated alterations in a blood–brain barrier model
... fact, MSC-derived EVs have been shown to protect TJ structure in tubular epithelial cells [144] and provide a wide array of neuroprotective and neurorepara- tive effects [145, ...this MSC action is ...
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IL-15 Generates IFN-γ-producing Cells Reciprocally Expressing Lymphoid-Myeloid Markers during Dendritic Cell Differentiation
... IL-15-differentiated bone marrow-derived cells (IL-15-DBMCs) is still under debate, particularly the generation of IFN-γ-producing innate cells such as premature NK (pre-mNK) cells, natural killer ...
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Exosomes from bone marrow mesenchymal stem cells enhance fracture healing through the promotion of osteogenesis and angiogenesis in a rat model of nonunion
... Methods: BMMSC-Exos were isolated and transplanted into the fracture site in a rat model of femoral nonunion (Exo group) every week. Moreover, equal volumes of phosphate-buffered saline (PBS) and exosome-depleted ...
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Effects of platelet-rich plasma on the activity of human menstrual blood-derived stromal cells in vitro
... Human platelet-rich plasma (PRP) is an artificial blood-derived product with the significant advantage of enabling autologous transplantation. In small volumes of plasma, the density of platelets in PRP is 5 – 10 ...
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