Bone morphogenetic protein 2 (BMP2)
Effects of dentin proteins, transforming growth factor beta 1 (TGF beta 1) and bone morphogenetic protein 2 (BMP2) on the differentiation of odontoblast in vitro
... Int I De\" BioI 36 491 503 (1992) 491 Original Artirle Effects of dentin proteins, transforming growth factor B 1 (TGFB 1) and bone morphogenetic protein 2 (BMP2) on the differentiation of odontoblast[.] ...
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Using poly(lactic-co-glycolic acid) microspheres to encapsulate plasmid of bone morphogenetic protein 2/polyethylenimine nanoparticles to promote bone formation in vitro and in vivo
... large bone defects is a major challenge, requiring sustained stimulation to continually promote bone formation ...locally. Bone morphogenetic protein 2 (BMP-2) plays an ...
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Bone morphogenetic protein 2 (BMP2) induces growth suppression and enhances chemosensitivity of human colon cancer cells
... of BMP2 is an unfavourable event in CRC pathogenesis and progression ...of BMP2 reduced viability of HCT116 CRC cells in vitro ...recombinant BMP2 to HCT116 cells led to similar results (Additional ...
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Original Article Effect of atorvastatin, 3-hydroxy-3-methylglutaryl coenzyme a reductase inhibitor (HMG-CoA) on the prevention of osteoporosis in ovariectomized rabbits
... of bone healing ...genes: bone morphogenetic protein 2 (BMP2), core-binding factor alpha 1 (Cbfa1), osteoprotegerin (OPG), and receptor activator for nuclear factor κB ligand ...
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Hypertrophy is induced during the in vitrochondrogenic differentiation of human mesenchymal stem cells by bone morphogenetic protein 2 and bone morphogenetic protein 4 gene transfer
... and bone formation when delivered as recombinant protein [38] or via genetically modified cells ...of bone marrow-derived MSCs and other effects may be seen when different cells are ...
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Effects of platelet-rich plasma on the activity of human menstrual blood-derived stromal cells in vitro
... of bone and cartilage regener- ation, in which PRP engraftment resulted in good outcomes and promoted the expression of particular functional genes, such as bone morphogenetic protein-2 ...
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Structure and expression of the chicken bone morphogenetic protein-2 gene
... A mutation in the Bmp-5 gene has been isolated: the mouse mutant "short ear", which displays localised cartilage defects (Kingsley et al, 1992; reviewed in Kingsley, 1994). The size, shape and number of many ...
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Specific detection of clinical samples, systematic functional investigations, and transcriptome analysis reveals that splice variant MUC4/Y contributes to the malignant progression of pancreatic cancer by triggering malignancy related positive feedback loops signaling
... 7; BMP2: Bone morphogenetic protein 2; cDNA: Complementary DNA; CI: Confidence interval; Ct: Threshold cycle value; CTHRC1: Collagen triple helix repeat-containing 1; DEGs: ...
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Heparin-mediated delivery of bone morphogenetic protein-2 improves spatial localization of bone regeneration
... radation of the alginate hydrogel, interstitial fluid flow, and competitive binding of other proteins to HMPs in the in vivo injury environment, which has previously only been simulated in vitro using fetal bovine serum ...
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How dietary arachidonic- and docosahexaenoic- acid rich oils differentially affect the murine hepatic transcriptome
... activator protein 1; APP, amyloid beta (A4) precursor protein; bHLH, basic helix-loop helix; BMP2, bone morphogenetic protein 2; bZIP, basic region- leucine zipper; CDK, ...
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Bone regenerative effect of recombinant human bone morphogenetic protein-2 after cyst enucleation
... without bone grafts, further research regarding growth factors, osteo- blasts, stem cells, and other components is needed to understand this process more fully ...[16]. Bone defects up to 3 cm in diameter ...
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Blockade of bone morphogenetic protein signaling potentiates the pro inflammatory phenotype induced by interleukin 17 and tumor necrosis factor α combination in rheumatoid synoviocytes
... of BMP2, BMP6, and BMP7 ligands was notably increased after culture with IL-17 and TNF-α and mainly when the two cytokines were used in combination (8-, 9-, and 20-fold increases for BMP2, BMP6, and BMP7, ...
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Identification of a bone morphogenetic protein type 2 receptor neutralizing antibody
... µL Protein G-coupled Dynabeads (Inv- itrogen 1003D) at room temperature for 30 min in 200 µL total volume with gentle ...human BMP2 (R&D Systems 892143) was added to the beads and incubated overnight at ...
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“Evolving Trends in Biopolymer Based Drug Delivery Systems: An Overview” by Soruba Evangeline, Vickram Sundaram, Ramesh Pathy Manian, Sridharan Balasundaram, India.
... structural protein, which gives structure and support to the tissues connecting them with the ...human bone morphogenetic protein 2 (rhBMP-2) was studied for bone ...
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Genetic analyses in a cohort of 191 pulmonary arterial hypertension patients
... BMPR1B: bone morphogenetic protein receptor type 1B; BMPR2: bone morphogenetic protein receptor type 2; BWA: Burrow-Wheeler Aligner; CAV1: caveolin 1; CNV: copy-number ...
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Organizing pneumonia in mice and men
... BMPs: bone morphogenetic proteins; BMPR1B: bone morphogenetic protein receptor type-1B; BO: bronchiolitis obliterans; BOOP: bronchiolitis obliterans organizing pneumonia; CCL2: C-C ...
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Azoramide, a novel regulator, favors adipogenesis against osteogenesis through inhibiting the GLP-1 receptor-PKA-β-catenin pathway
... G protein-coupled re- ceptors, which are highly expressed on islet β cells ...Ca 2+ are vital components in the biosynthesis and secretion of ...the bone-inducing ef- fects of MSC in response to ...
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Osteoblast differentiation of rabbit adipose-derived stem cells by polyethylenimine-mediated BMP-2 gene transfection in vitro.
... Transcription factors are important for inducing differentiation in stem cells. BMPs are members of the transforming growth b superfamily and consist of over 20 isoforms (Wozney et al., 1988). Among these, BMP-2 ...
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Lysyl oxidase regulates transforming growth factor-[beta]1 function in bone
... that protein synthesis was important for the incorporation of copper into enzyme but N-linked glycosylation had no effect on secretion of the copper that was bound to ...during protein trafficking through ...
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Increased plasma BMP-2 levels are associated with atherosclerosis burden and coronary calcification in type 2 diabetic patients
... Vascular calcification is common in diabetes and is as- sociated with high risk of cardiovascular events. Lesion length, plaque burden, necrotic core, and calcium con- tent have all been shown to be significantly higher ...
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