Bone Morphogenetic Protein (BMP)
Immunohistochemical expression of osteocalcin, transforming growth factor beta 1 and bone morphogenetic protein 7 in fibrous dysplasia and ossifying fibroma of the jaw bones (a comparative study)
... increased bone mineral density. It is therefore, used as biomarker for bone formation process and also has a role in regulation of osteoblast function (Lee et ...in bone matrix, it is a regulator of ...
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Identification of a bone morphogenetic protein type 2 receptor neutralizing antibody
... Objective: The bone morphogenetic protein (BMP) signaling pathway comprises the largest subdivision of the trans- forming growth factor (TGFβ) superfamily. BMP signaling plays essential roles in both ...
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Role of osteogenic protein-1/bone morphogenetic protein-7 in spinal fusion
... Osteogenic protein-1 (OP-1), also known as bone morphogenetic protein-7 (BMP-7), is a protein in the TGF-β family of cellular proteins that has shown potential for application in ...
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Bone Morphogenetic Protein Receptor in the Osteogenic Differentiation of Rat Bone Marrow Stromal Cells
... of bone marrow stromal cells (BMSCs). Bone morphogenetic protein (BMP) signaling has important effects on the process of ...of bone morphogenetic protein receptor (BMPR) ...
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Using poly(lactic-co-glycolic acid) microspheres to encapsulate plasmid of bone morphogenetic protein 2/polyethylenimine nanoparticles to promote bone formation in vitro and in vivo
... large bone defects is a major challenge, requiring sustained stimulation to continually promote bone formation ...locally. Bone morphogenetic protein 2 (BMP-2) plays an important role ...
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The extracellular regulation of bone morphogenetic protein signaling
... Tsg protein called Crossveinless (Tsg2), where it is released for signaling by the Tolloid-related protease (not ...BMP, bone morphogenetic protein; Cv2, Cv-2 (Crossveinless 2; BMPER); Sog, ...
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Evaluation of specific germ cell genes expression in mouse embryonic stem cell-derived germ cell like cells treated with bone morphogenetic protein 4 in vitro
... transmitting factor in male gonads is produced, which terminates cell cycle at G1, and prevents the cells from entering meiosis (4). Whether a meiosis-inducing factor (5) or an autonomous event is required for GCs to ...
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Bone morphogenetic protein expression in human atherosclerotic lesions
... In addition, cells cultured from the aortic wall formed calcified nodules similar to those found in bone cell cultures and expressed bone morphogenetic protein-2a with prolonged culture.[r] ...
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Allogeneic morphogenetic protein vs. recombinant human bone morphogenetic protein-2 in lumbar interbody fusion procedures: a radiographic and economic analysis
... human bone morphogenetic protein-2 (Infuse, Medtronic ...ectopic bone formation and potentially cancer, leading clinicians to question the clinical benefit versus patient safety ...
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Evaluation of a bone morphogenetic protein 6 variant as a cause of iron loading
... Background: Atypical iron overload without variation in the five clinically associated hereditary hemochromatosis genes is now recognized; however, their etiology remains unknown. Since the identification of iron ...
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Blockade of bone morphogenetic protein signaling potentiates the pro inflammatory phenotype induced by interleukin 17 and tumor necrosis factor α combination in rheumatoid synoviocytes
... Introduction: Bone morphogenetic proteins (BMPs) are multifunctional secreted growth factors regulating a broad spectrum of functions in numerous ...
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Signalling via type IA and type IB bone morphogenetic protein receptors (BMPR) regulates intramembranous bone formation, chondrogenesis and feather formation in the chicken embryo
... ABSTRACT Bone morphogenetic proteins (BMPs) signal via complexes of type I and type II ...regulating bone, cartilage and feather formation in the ...
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Hypertrophy is induced during the in vitrochondrogenic differentiation of human mesenchymal stem cells by bone morphogenetic protein 2 and bone morphogenetic protein 4 gene transfer
... gous bone marrow stromal cells for the repair of full-thickness articular cartilage defects in humans ...with bone morphogenetic proteins (BMPs), members of the TGF-β ...endochondral bone ...
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Bone morphogenetic protein 4 (BMP4) signaling in retinoblastoma cells
... Bone morphogenetic proteins (BMPs) - expressed in the developing retina – are known to be involved in the regulation of cell proliferation and apoptosis in several tumor ...
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Structure and expression of the chicken bone morphogenetic protein-2 gene
... The Bmp-5, 6, 7 and 8 genes are on average 70% identical to the Drosophila 60A gene (Lyons et at, 1989; Ozkaynak et al, 1990; Ozkaynak et al, 1992), whereas 60A has only 53% amino acid sequence identity with dpp, and ...
362
Bone Morphogenetic Protein Coating on Titanium Implant Surface: a Systematic Review
... Bouyer at al. [14] made an experimental analysis in order to assess the effect of BMP-2 concentrations with EDC10 (ethylene imine linear poly) and EDC30 crosslinking levels. It was assessed while trying to fill ...
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The involvement of follistatin like protein 1 in osteoarthritis by elevating NF κB mediated inflammatory cytokines and enhancing fibroblast like synoviocyte proliferation
... disco-interacting protein 2 homolog a (DIP2a) from Drosophila was a candidate receptor for FSTL1 in endothelial cells ...TGF-β, bone morphogenetic protein (BMP)-2⁄4, and their receptors ...
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The role of bone morphogenetic protein-4 in the developing chick eye
... The effects of applying BM P-2 protein and B m p -4 viral supernatant on cell differentiation were analysed by immunofluorescent detection of a mature neurofilament m arker, neurofilament-200. This antibody is ...
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The essential role of bone morphogenetic protein (BMP) signaling in organogenesis
... Activated Protein Kinases (MAPKs) 70,77 , Ca ++ - and Calmodulin-dependent kinase II (Cam Kinase II) 78 , Cyclin-dependent kinase (CDKs) 79 , and G protein-coupled Receptor Kinase 2 (GRK-2) 80 ...
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Enhanced in vivo osteogenesis by nanocarrier-fused bone morphogenetic protein-4
... A bone hole was made in the distal diaphysis of the femur with a ϕ ...exclude bone ingrowth by spontaneous ...each protein fluorescently labeled was implanted as described ...
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