bovis and BCG
Mycobacterium bovis Bacillus Calmette-Guerin (BCG) and BCG-based Vaccines Against Tuberculosis
... 결핵균(Mycobacterium bovis)에서 유래한 것으로, 프랑스 파스퇴르 연구소의 Calmette와 Guérin이 Mycobacterium bovis를 1908년부터 1920년까지 총 231회의 계대 배양을 통하여 병원성이 약독화된 균 주이다 ...여러 BCG 균주가 파 생되기 시작하였다 ...
8
The effect of glutamate homeostasis on the survival of M. bovis BCG
... 5.5.3 Post alignment analysis of VCF files The VCF files generated by the process explained above (Chapter 5, Section 5.5.2) contain either a set of SNP’s or IN/DEL’s. These variants are indicative of SNP’s or IN/DELS ...
108
Identification of Surrogates and Correlates of Protection in Protective Immunity against Mycobacterium bovis Infection Induced in Neonatal Calves by Vaccination with M. bovis BCG Pasteur and M. bovis BCG Danish
... Mycobacterium bovis bacillus Calmette-Gue ´rin (BCG) induces a signif- icant degree of protection against infection with virulent ...M. bovis, the causative agent of bovine tuberculosis ...of ...
7
Immune Reactivity of Mycobacterium Bovis (Strain BCG) and Mycobacterium Vaccae
... Interfron-γ, TNF-α and macrophage activation do not meet appropriately a virulent mycobacterial infection because these responses are activated with greater vigor by a virulent mycobacterial strain than by a low-virulent ...
11
A novel method for monitoring Mycobacterium bovis BCG trafficking with recombinant BCG expressing green fluorescent protein.
... wild-type BCG by both human bladder tumor cell line T-24 and mouse bladder tumor cell line MBT-2 ...wild-type BCG phagocytosis by both T-24 and MBT-2 cells in that maximal internalization was observed at 16 ...
8
Development of Diagnostic Reagents To Differentiate between Mycobacterium bovis BCG Vaccination and M. bovis Infection in Cattle
... Mycobacterium bovis holds the best long-term prospect for tuberculosis control in British ...M. bovis so that test-and-slaughter-based control strategies can continue alongside ...M. bovis BCG ...
8
Protection Induced by Simultaneous Subcutaneous and Endobronchial Vaccination with BCG/BCG and BCG/Adenovirus Expressing Antigen 85A against Mycobacterium bovis in Cattle
... M. bovis, the main causative agent of bTB, conferred by BCG delivered subcutaneously, endobronchially or by the new strategy of simultaneous immunisation by both ...with BCG and endobronchial ...
12
Differentiation between Mycobacterium bovis BCG-Vaccinated and M. bovis-Infected Cattle by Using Recombinant Mycobacterial Antigens
... following BCG vaccination and M. bovis infection in a natural ...M. bovis has previously been found to result in the majority of nonvacci- nated and a small number of BCG-vaccinated animals ...
5
Glutamate dehydrogenase is required by mycobacterium bovis BCG for resistance to cellular stress
... M. bovis BCG, despite their in vitro essentiality in ...M. bovis BCG as a model for ...M. bovis BCG physiology, including the use of glutamate as a carbon source and resistance ...
14
Evaluation of the Immunogenicity of Mycobacterium bovis BCG Delivered by Aerosol to the Lungs of Macaques
... Mycobacterium bovis BCG vaccine provides limited protection, whereas aerosol delivery has been shown to enhance efficacy in experimental ...aerosol-delivered BCG vaccine. Aerosol delivery of ...
12
Extracellular and Cytosolic Iron Superoxide Dismutase from Mycobacterium bovis BCG
... Dongguk University, Kyoungju City, Kyungpook 780-714, 2 Korea Received 6 March 1998/Returned for modification 24 June 1998/Accepted 1 September 1998 Two forms of iron superoxide dismutase (SOD) were purified from cell ...
6
T-Cell mRNA Expression in Response to Mycobacterium bovis BCG Vaccination and Mycobacterium bovis Infection of White-Tailed Deer
... Mycobacterium bovis provides insight into mechanisms of pathogen control and may provide clues to development of effective vaccine ...M. bovis BCG strain Pasteur or BCG strain ...M. ...
7
Specific Differentiation betweenMycobacterium bovis BCG and Virulent Strains of theMycobacterium tuberculosis Complex
... tested BCG strains exclusively contained 77-bp MIRUs within the senX3-regX3 IR, whereas all non-BCG ...MIRU. BCG strains contained either one, two, or three 77-bp ...in BCG strains and its ...
6
Use of Antigen-Specific Interleukin-2 To Differentiate between Cattle Vaccinated with Mycobacterium bovis BCG and Cattle Infected with M. bovis
... M. bovis BCG-vaccinated or uninfected controls provides the possi- bility that IL-2 could make a useful addition to the DIVA test toolbox to distinguish vaccinated from ...M. bovis-infected individ- ...
7
Use of Antigen-Specific Interleukin-2 To Differentiate between Cattle Vaccinated with Mycobacterium bovis BCG and Cattle Infected with M. bovis
... M. bovis BCG-vaccinated or uninfected controls provides the possi- bility that IL-2 could make a useful addition to the DIVA test toolbox to distinguish vaccinated from ...M. bovis-infected individ- ...
7
Humoral Immune Responses of White-Tailed Deer (Odocoileus virginianus) to Mycobacterium bovis BCG Vaccination and Experimental Challenge with M. bovis
... Mycobacterium bovis infection as well as for the characterization of disease progression and the efficacy of intervention strategies in several ...M. bovis antigens by white-tailed deer vaccinated with ...
7
The role of glutamine oxoglutarate aminotransferase and glutamate dehydrogenase in nitrogen metabolism in Mycobacterium bovis BCG
... (TIF) Figure S3. Analysis of single colonies obtained from 22 day old Δgdh –N7H9 + 3mM L-Glu cultures. A) Arrangement of genes in the chromosomal region of M. bovis BCG where gdh is located. B) Arrangement ...
9
Role for Gr-1+ Cells in the Control of High-Dose Mycobacterium bovis Recombinant BCG
... Recombinant BCG Michael ...Mycobacterium bovis bacillus Calmette-Guérin (BCG) is an attractive target for development as a live vaccine vector delivering transgenic antigens from HIV and other ...of ...
8
Stable Expression of Lentiviral Antigens by Quality-Controlled Recombinant Mycobacterium bovis BCG Vectors
... M. bovis BCG, given its pervasive use worldwide, well-estab- lished safety profile, and readily available genetic tools, is of particular interest to the vaccine design ...of BCG as a recombinant ...
16
Vaccination with a BCG Strain Overexpressing Ag85B Protects Cattle against Mycobacterium bovis Challenge
... Mycobacterium bovis is the causative agent of tuberculosis in cattle but also infects other animals, including ...by BCG is not complete. In order to improve the protection efficacy of BCG, in this ...
10