C-terminus
Role of the FtsA C Terminus as a Switch for Polymerization and Membrane Association
... the C terminus and the ATP-binding pocket (5), suggesting that a weak membrane affinity of FtsA monomers should be compen- sated for by the protein ...the C-terminal region and, consequently, of the ...
9
The Rag2 C Terminus Participates in Repair Pathway Choice in Vivo and Suppresses Lymphomagenesis
... RAG2's C-terminus allows a-NHEJ to repair RAG-mediated DSBs in developing lymphocytes from both c-NHEJ- proficient and c-NHEJ-deficient mice, demonstrating that the V(D)J recombinase ...
131
The C Terminus of Foamy Retrovirus Gag Contains Determinants for Encapsidation of Pol Protein into Virions
... Foamy viruses (FV) differ from orthoretroviruses in many aspects of their replication cycle. A major difference is in the mode of Pol expression, regulation, and encapsidation into virions. Orthoretroviruses synthesize ...
8
The C Terminus of Hepatitis C Virus NS4A Encodes an Electrostatic Switch That Regulates NS5A Hyperphosphorylation and Viral Replication
... NS4A C-terminal acidic domain. The C terminus of NS4A contains a short acidic region that is highly conserved among diverse HCV isolates ...NS4A C termini of pestiviruses and GB virus B (not ...
14
Role of the C Terminus of Lassa Virus L Protein in Viral mRNA Synthesis
... A, C, D, and E] of standardized relative light units [sRLU] as a percentage of the wild ...the C terminus of L protein were exchanged with ...
5
Mechanical stimuli induce cleavage and nuclear translocation of the polycystin 1 C terminus
... Cell culture, transfection, antibodies, and immunofluorescence. Cell lines were grown in α-MEM (Invitrogen) (MDCK, CHO and Cos-7) or DMEM (Invitrogen) (HEK) supplemented with 10% FBS at 37°C. Transient ...
12
Core Protein of Pestiviruses Is Processed at the C Terminus by Signal Peptide Peptidase
... with C termini around tryptophan 254 almost comigrated with core protein from CSFV virions in immuno- blot analysis ...C terminus. Recently a cleavage that occurs within the membrane-spanning ...
7
Hepatitis A Virus Capsid Protein VP1 Has a Heterogeneous C Terminus
... the C-terminal amino acid(s) of pro- teins is still one of the more challenging tasks in ...Chemical C-terminal sequence analysis analogous to the N- terminal sequence analysis of protein (Edman ...
9
The C Terminus of the Polerovirus P5 Readthrough Domain Limits Virus Infection to the Phloem
... Phloem restriction of PLRV appears to be a self-imposed trait. Approximately 4 months p.i., multiple young leaves on several SYG-infected plants manifested WT-like symptoms. Whole-leaf tissue immunoblots of four of these ...
11
The transactivation domain of adenovirus E1A interacts with the C terminus of human TAF(II)135.
... The proposal that an interaction between the C terminus of hTAF II 135 and the CR3 region of E1A is important for E1A FIG. 3. Regions of E1A CR3 involved in binding the C terminus of hTAF II ...
6
A PHD Finger Motif in the C Terminus of RAG2 Modulates Recombination Activity
... and C) ...the C terminus being dependent on the last seven amino acids, be a manifestation of the high specific activity of these proteins, or ...strand. C, darker exposure of gel in B, lanes ...
12
Derivation of ligands for the complement C3a receptor from the C-terminus of C5a
... the C termini, as well as a conserved Tyrosine (Y) two amino acids before the LWR ...the C termini in the superagonist ‘W -W-G-K-K-Y-R-A-S-K-L-G-L-A- R’ (Bellows-Peterson et ...the C terminus ...
21
Changes in the accessibility of the HIV 1 Integrase C terminus in the presence of cellular proteins
... accessible C-terminal tag. C-terminal masking was not detected in studies where IN was over-expressed in cell lines ...the C-terminus is accessible requiring high IN concentrations, and ...
10
Roles of the C Terminus of Armadillo in Wingless Signaling in Drosophila
... the C-terminal region, the bcat C terminus may not function effectively in ...Arm’s C terminus diminishes, but does not eliminate its signaling ...of C-terminally ...
14
Degrons at the C Terminus of the Pathogenic but Not the Nonpathogenic Hantavirus G1 Tail Direct Proteasomal Degradation
... the C-terminal hydrophobic ...51 C-terminal residues of the NY-1V G1 tail (NY-1V-delC51) abrogates G1 tail degradation ...of C-termi- nally truncated mutants lacking 5, 14, or 30 residues at the G1 ...
9
A C-terminus Mitochondrial-localization Region and BH3 Domain of Puma are Required for Apoptotic Function
... the c-terminus that regulates its localization to the ...the c- terminus of Puma that is essential for both mitochondrial-localization and apoptotic function of the ...the ...
121
The N Terminus and C Terminus of Herpes Simplex Virus 1 ICP4 Cooperate To Activate Viral Gene Expression
... one C terminal, are largely responsible for the activation functions of ...the C-ter- minal activation domain (n208) efficiently activates many early genes, whereas late genes are poorly activated, and ...
13
Structural insights into the dynamics and function of the C terminus of the E coli RNA chaperone Hfq
... by small trans-encoded RNAs. Hfq proteins of dif- ferent bacteria comprise an evolutionarily conserved core, whereas the C-terminus is variable in length. Although the structure of the conserved core has ...
18
C Terminus of Nce102 Determines the Structure and Function of Microdomains in the Saccharomyces cerevisiae Plasma Membrane
... and C termini are oriented toward the cytosol. Deletion of the C terminus or even of its last 6 amino acids does not disturb protein trafficking, but it seriously affects the formation of ...the ...
9
Cleavage of dengue virus NS1-NS2A requires an octapeptide sequence at the C terminus of NS1.
... Dengue type 4 virus D4 sequence at and near the NS1-NS2A junction including the eight-amino-acid cleavage site positions P-1 to P-8 14 was used for alignment and comparison with the anal[r] ...
5