Cancer cell invasion
Original Article miR-126 regulated breast cancer cell invasion by targeting ADAM9
... regulated cancer cell invasion, we performed a trans-well assay by transfecting miR-126 mimics or NC into MCF-7 and MDA-MB-231 ...breast cancer cell lines after transient ...of ...
7
Mathematical model for cancer cell invasion of tissue
... Cancer cell invasion of tissue is a complex biological process which during cell migration through extracellular matrix, facilitated by the secretion of degradative enzymes, is a central ...
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3D Traction Forces in Cancer Cell Invasion
... Cell invasion through a dense three-dimensional (3D) matrix is believed to depend on the ability of cells to generate traction ...of cell tractions during invasion in 3D, we present a ...
9
Numerical Simulation of a Mathematical Model for Cancer Cell Invasion
... 1. Chaplain MA J and Lolas G (2005) Mathematical modelling of cancer cell invasion of tissue: The role of the urokinase plasminogen activation system. Mathemat Models Methods Applied Sci 15(11): ...
5
Hijacking a morphogenesis proteinase for cancer cell invasion
... tumour cell invasion in ...drives invasion in both developmental duct penetration and cancer cell invasion but the cellular compartments that control the Mmp14-mediated ...
6
INPP4B suppresses prostate cancer cell invasion
... We next tested whether INPP4B regulates IL-8 and PAK6 by opposing PKC signaling, which is activated by the INPP4B substrate PI(4,5)P2. In parental PC-3 cells, PKC inhibition with bisindolylmaleimide I (BIM-I) decreased ...
16
TGF-beta and BMP in breast cancer cell invasion
... breast cancer that infiltrate into distant organs die due to restric ons in the host microenvironment ...breast cancer cells may ...breast cancer cells are osteotropic, leading to the "seed and ...
199
Original Article Silencing of the long non-coding RNA NEAT1 suppresses ovarian cancer cell proliferation, migration and invasion
... ovarian cancer patients ...ovarian cancer cells [23]. TGF-β1 is involved in EMT and cancer cell invasion ...the invasion-pro- moting function by regulating TGF-β1, Snail1, MMP-2 ...
10
<p>SPOCK1 Involvement in Epithelial-to-Mesenchymal Transition: A New Target in Cancer Therapy?</p>
... SPOCK1 is a proteoglycan with systemic physiological functions. The anticancer effects have been investigated widely. SPOCK1 plays an important role in cancer prolif- eration and chemotherapy resistance and ...
9
Schwann cells induce cancer cell dispersion and invasion
... neural cell adhesion mole- cule 1 (NCAM1) ...perineural invasion, with nerve-secreted factors, including glial cell line–derived neurotrophic factor (GDNF), enhancing cancer cell ...
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Effect of high-intensity focused ultrasound (HIFU) combined with radiotherapy on tumor malignancy in patients with advanced pancreatic cancer and evaluation of side effects
... pancreatic cancer, perineural invasion is a striking feature of advanced pancreatic cancer, it is characterized by cancer cell growth along the nerve or growth within the nerve sheath, ...
5
Research on the Solution of Cell Invasion Model with Free Boundary
... and invasion of cancer cells; however, studies on the cancer cell invasion model with free boundary are fairly ...modified cancer cell invasion model with free ...
20
<p>GPX2 suppression of H<sub>2</sub>O<sub>2</sub> stress regulates cervical cancer metastasis and apoptosis via activation of the β-catenin-WNT pathway</p>
... regulate cancer progression by regulating the levels of hydroperoxides inside ...ME180 cell line, whereas the opposite result was found in HeLa cells over- expressing ...
13
Mathematical modelling of cancer invasion : the multiple roles of TGF β pathway on tumour proliferation and cell adhesion
... on cell– cell and cell–matrix interactions, but paying particular attention to the opposite role of TGF-β on early stage versus late stage cancer ...for cell–cell and ...
34
Increased NOS2 predicts poor survival in estrogen receptor–negative breast cancer patients
... breast cancer patients, we examined NOS2 expression and its association with tumor markers and survival in 248 breast ...breast cancer with poor prognosis. In cell culture, NO only induced selected ...
13
Hallmarks of glycosylation in cancer
... overcome cell-cell adhesion and then invade surrounding ...tumour cell invasiveness, including the ability to disseminate through the circulation and metastasise into distant organs ...[9]. ...
12
ZFAS1: a novel tumor-related long non-coding RNA
... OS cell lines and growth and metastatic model of ...AML cell lines compared with T lymphocytic leukemia cell line or Burkitt’s lymphoma cell line, then they found knockdown of ZFAS1 impeded ...
8
<p>Anticancer activity of 1, 25-(OH)<sub>2</sub>D<sub>3</sub> against human breast cancer cell lines by targeting Ras/MEK/ERK pathway</p>
... Cell invasion assay was performed using a polyethylene tere- phthalate membrane (8 µ m pore size) with Millicell hanging cell culture inserts and BD Matrigel ...breast cancer cells were ...
12
Rapamycin and WYE-354 suppress human gallbladder cancer xenografts in mice
... Several studies have demonstrated the therapeutic efficacy of mTOR inhibitors on suppressing tumor growth in a number of solid tumors on human subcutaneous growing xenografts [19, 21, 60] and in many phase I–III clinical ...
12
S100A10 silencing suppresses proliferation, migration and invasion of ovarian cancer cells and enhances sensitivity to carboplatin
... clinicopathological characteristics, including residual tumor size, level of CA125 in primary tumors and FIGO stage. The results reported here are partly con- sistent with the findings in lung adenocarcinomas, whereby ...
11