CD150/SLAM
Identification of Key Residues in Virulent Canine Distemper Virus Hemagglutinin That Control CD150/SLAM-Binding Activity
... uphold SLAM-dependent ...of SLAM-dependent fusion activity (H- SLAM-blind; HSB ...in SLAM-binding activity but presumably were involved in con- trolling SLAM-dependent F triggering ...
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Receptor (SLAM [CD150]) Recognition and the V Protein Sustain Swift Lymphocyte-Based Invasion of Mucosal Tissue and Lymphatic Organs by a Morbillivirus
... Experimental infections of ferrets with canine distemper virus (CDV) recapitulate many hallmarks of measles: rash, high fever, viremia, depression of delayed-type hypersensitivity responses, lowered leukocyte counts, and ...
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Measles Virus Infection of Alveolar Macrophages and Dendritic Cells Precedes Spread to Lymphatic Organs in Transgenic Mice Expressing Human Signaling Lymphocytic Activation Molecule (SLAM, CD150)
... (SLAM, CD150) with human-like tissue ...human SLAM, and it was observed that MV infection temporarily enhanced SLAM ...human SLAM with human-like tissue ...
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Measles Virus Selectively Blind to Signaling Lymphocytic Activation Molecule (SLAM; CD150) Is Attenuated and Induces Strong Adaptive Immune Responses in Rhesus Monkeys
... (SLAM; CD150) (10, 15, 35). SLAM is an immune cell- specific protein expressed on the surface of thymocytes, acti- vated lymphocytes, mature dendritic cells, and activated macrophages (4, ...
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High Pathogenicity of Wild-Type Measles Virus Infection in CD150 (SLAM) Transgenic Mice
... human CD150 (SLAM), the receptor for both wild-type and vaccine MV ...first SLAM transgenic model where MV infection induces a severe pathogenic ...human SLAM in these transgenic mice, while ...
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CD150 (SLAM) Is a Receptor for Measles Virus but Is Not Involved in Viral Contact-Mediated Proliferation Inhibition
... (SLAM; CD150), which is identical to the MV receptor recently found by ...proteins, SLAM is downregulated from the cell surface of activated PBL and cell ...of SLAM does not correlate with the ...
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Measles Virus Infection of SLAM (CD150) Knockin Mice Reproduces Tropism and Immunosuppression in Human Infection
... called CD150) acts as a cellular receptor for MV (13, 21, 55). SLAM, a self-ligand glycoprotein, is expressed on immature thymocytes, activated T and B cells, mature dendritic cells (DCs), and macrophages ...
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SLAM (CD150)-Independent Measles Virus Entry as Revealed by Recombinant Virus Expressing Green Fluorescent Protein
... uses SLAM as a receptor, whereas the Edmonston strain can use both SLAM and CD46 as receptors), IC323- EGFP caused cytopathic effects (CPE) in SLAM-positive cells, such as B95a, Vero/SLAM, ...
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Canine Distemper Virus Fusion Activation: Critical Role of Residue E123 of CD150/SLAM
... of SLAM and H are nonetheless considered to be (at least partially) maintained even with SLAM variants harboring combined mutations at the interactive site, then the regulatory residues identified may not ...
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Contribution of Matrix, Fusion, Hemagglutinin, and Large Protein Genes of the CAM-70 Measles Virus Vaccine Strain to Efficient Growth in Chicken Embryonic Fibroblasts
... MV, an enveloped virus with a nonsegmented negative- strand RNA genome, belongs to the genus Morbilivirus in the family Paramyxoviridae. The MV genome of 15,894 nucleotides (nt) consists of six tandem-linked genes that ...
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HIV-1 Infection Ex Vivo Accelerates Measles Virus Infection by Upregulating Signaling Lymphocytic Activation Molecule (SLAM) in CD4+ T Cells
... as CD150), and attenu- ated vaccine strains can utilize both SLAM and CD46 ...However, SLAM remains a major receptor of MV in lymphoid organs and plays an important role in a systemic MV ...on ...
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Morbilliviruses Use Signaling Lymphocyte Activation Molecules (CD150) as Cellular Receptors
... bovine SLAM-expressing CHO ...in SLAM-expressing CHO cell clones after infection with the respective viruses, confirming that SLAM acts at the virus entry step (as a cellular ...of SLAM as a ...
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Measles virus blind to its epithelial cell receptor remains virulent in rhesus monkeys but cannot cross the airway epithelium and is not shed
... Measles virus (MV) is one of the most contagious human patho- gens (1). It is transmitted by aerosols, infecting a new host via the upper respiratory tract. It is currently thought that MV, a member of the Morbillivirus ...
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Real time Visual SLAM for mobile robot navigation and object detection : a thesis presented in partial fulfilment of the requirement for the degree of Doctor of Philosophy in Engineering at Massey University, Albany, New Zealand
... solving SLAM problems, a practical solu- tion for a mobile robot at a critical level of effectiveness and robustness is still ...to SLAM based on a strategy of repeating ...
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Tactile SLAM with a biomimetic whiskered robot
... In this paper we present an alternative approach to strengthen mapping, using properties of whisker sensors without the need for multiscans or rectilinear assumptions. Unlike infra-red or sonar sensors, which collect ...
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Real time Visual SLAM for mobile robot navigation and object detection : a thesis presented in partial fulfilment of the requirement for the degree of Doctor of Philosophy in Engineering at Massey University, Albany, New Zealand
... Visual SLAM method and an iterated video frames module integrated in the EKF are ...Visual SLAM method can handle feature de- tection and corresponding depth measurements in an efficient way, and the ...
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Designing an Embedded System for Autonomous Building Map Exploration Robot
... SLAM (Simultaneous localization and mapping) technique is used by robots and autonomous vehicles to build up a map within an unknown environment, or to update a map within a known environment, while at the same ...
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Simultaneous Localization and Mapping Solutions Using Monocular and Stereo Visual Sensors with Baseline Scaling System
... the SLAM problem using several methods of ...robust SLAM implementation. SLAM process challenges are cen- tered on methods enabling large-scale implementations in increasingly unstruc- tured ...
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Slamming of large high speed catamarans in irregular seas
... predict slam occurrence rates and severity by a time-domain numerical simulation would make an extremely valuable structural design ...loading, slam occurrence rates, slam loads and also the fatigue ...
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Mapping and Navigation for Indoor Robots under ROS: An Experimental Analysis
... which SLAM package should be used given the application ...the SLAM subsystem must deliver estimates for robot navigation, as is the case of applications involving autonomous navigation, this question is ...
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