Cell cycle regulator
Human HTm4 is a hematopoietic cell cycle regulator
... of cell cycle progression is critical for the constant self-renewal, differentiation, and homeostasis of the hematopoietic ...common cell cycle ...define cell-type or lineage speci- ...
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POLYMORPHISMS IN CELL CYCLE REGULATOR GENE P27KIP1 AND P16INK4A AND LUNG CANCER RISK IN A BANGLADESHI POPULATION
... in cell cycle checkpoints is awfully common among almost all cancers including lung ...susceptible cell cycle regulator and to harmonize between genetic polymorphism and risk factors of ...
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Novel Roles of Cell Cycle Regulator E2f1 in the Cns: Implications for Synaptic Damage in HIV-Associated Neurocognitive Disorders
... Human immunodeficiency virus (HIV)-associated dementia (HAD) is a common neurological disorder associated with HIV infection. Pathologic studies of the brains of patients with HAD suggest an inflammatory mechanism in the ...
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Functional Interactions between Herpesvirus Oncoprotein MEQ and Cell Cycle Regulator CDK2
... Cell cycle-dependent cytoplasmic translocation of MEQ ...and cell cycle ...the cell cycle and under different growth ...several cell cycle-blocking agents, which ...
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Original Article The cell cycle regulator p27 Kip1 is associated with urothelial bladder cancer invasion
... with muscle invasive phenotype of the disease. Several attempts have been made in the past to analyze the predictive value of the cell cycle regulators including p27 in bladder cancer [10, 15-17]. Our data ...
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Temporal and spatial expression of the cell cycle regulator cul 1 in Drosophila and its stimulation by radiation induced apoptosis
... the cell cycle is controlled by a variety of processes including the synthesis or activation of regulatory proteins as well as the destruction of ...Moreover, cell-cycle transitions are ...
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MicroRNA 497 increases apoptosis in MYCN amplified neuroblastoma cells by targeting the key cell cycle regulator WEE1
... MNA cell lines resulted in sig- nificantly increased apoptosis, making this an attractive potential target for novel therapy approaches in high- risk neuroblastoma ...neuroblastoma cell lines, resulting in ...
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Functional and Physical Consequence of Human Immunodefficiency Virus Transactivator TAT Interaction with Human Cell Cycle Regulator p53
... a cell porater apparatus (Gibco/BRL, Gaithersburg, MD). Cell mixtures were electroporated at 800 µF, 230 volts, in RPMI 1640 media without fetal calf ...
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Periplasmic protein EipA determines envelope stress resistance and virulence in Brucella abortus
... abortus cell envelope play a major role in its ability to infect, colonize and survive inside mammalian host ...essential cell cycle regulator, ...a cell chaining phenotype, providing ...
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meis1 regulates cyclin D1 and c myc expression, and controls the proliferation of the multipotent cells in the early developing zebrafish eye
... in cell cycle control is mediated by meis1 regulating cyclin D1 and c-myc ...in cell clones is incompatible with the normal differentiation of the meis1- expressing cells, which in turn tend to ...
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Genomic aberrations in cell cycle genes predict progression of KIT-mutant gastrointestinal stromal tumors (GISTs)
... of cell cycle regulator genes in GIST, we per- formed focused testing of the genomic status (mutation, copy number variation, and LOH) of three of these genes (CDKN2A, RB1, and TP53) in an ...
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Original Article SGK1 protein expression is a prognostic factor of lung adenocarcinoma that regulates cell proliferation and survival
... enocarcinoma cell lines. Cell proliferation, cell cycle distribution, and apoptosis were characterized in the absence and presence of SGK1 ...G2 cell cycle arrest and reduced ...
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Drosophila Hfp negatively regulates dmyc and stg to inhibit cell proliferation
... In addition to regulating splicing of pre-mRNA, mammalian FIR is also an important regulator of Myc gene activity (Eisenman, 2001; Liu et al., 2000). Expression of Myc is tightly regulated, at the level of ...
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Cell cycle regulation of the stem loop binding protein : a key regulator in histone mRNA metabolism
... The S/G2 transition is one of the least understood stages of cell cycle. Here, we introduce Cyclin A/Cdk1 as player in this stage where it triggers degradation of SLBP as a mechanism to end histone ...
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Circular RNAs negatively regulate cancer stem cells by physically binding FMRP against CCAR1 complex in hepatocellular carcinoma
... FMRP mainly functions in the nervous system, where it acts as an RBP and controls the translation of its target mRNAs [30]. FMRP1 gene knockdown causes the relatively common genetic intellectual disability, fragile X ...
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The Role of Spy1 Protein Regulation In Breast Cancer
... in cell cycle ...the cell ensures the proper timing of cell cycle events ...the cell cycle. The importance of Speedy/RINGO proteins in the cell cycle is ...
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Geminivirus-Induced Gene Silencing of the Arabidopsis RETINOBLASTOMA-RELATED
... the cell cycle and depends on the proper coordination of spatial and temporal ...the cell cycle during G1, and whether or not a cell progresses into S-phase depends in large part on the ...
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Mcs4, a Two-Component System Response Regulator Homologue, Regulates the Schizosaccharomyces pombe Cell Cycle Control
... RUSSELL, 1997 Mcs4 mitotic catas- trophe suppressor regulates the fission yeast cell cycle through the Wikl-WislSpcl kinase cascade. HIETER, 1989 A system of shuttle vecto[r] ...
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Protein arginine methylation: an emerging regulator of the cell cycle
... of cell cycle; GADD45: growth arrest and DNA damage-inducible 45α; GAR: glycine–arginine rich; GSK3β: glycogen synthase kinase 3 β; H: histidine; hnRNPUL1: heterogenous nuclear ribonucleo protein; INCENP: ...
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Building Positive Future Orientations: The Role of Natural Mentors in the Lives of African American Girls
... desired cell characteristics when subjected to low serum concentrations (Ades et ...endothelial cell model creates aberrant results using ...B+C cell culture as demonstrated by gross morphology when ...
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