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chemical genomics

Chemical Genomics Identifies the PERK Mediated Unfolded Protein Stress Response as a Cellular Target for Influenza Virus Inhibition

Chemical Genomics Identifies the PERK Mediated Unfolded Protein Stress Response as a Cellular Target for Influenza Virus Inhibition

... Chemical Genomics Identifies the PERK Mediated Unfolded Protein Stress Response as a Cellular Target for Influenza Virus Inhibition Chemical Genomics Identifies the PERK Mediated Unfolded Protein Stre[.] ...

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Chemical genomics: a key to the epigenome   An interview with Minoru Yoshida

Chemical genomics: a key to the epigenome An interview with Minoru Yoshida

... the Chemical Genomics Research Group as well as the Chief Scientist of the Chemical Genetics Laboratory in the RIKEN Advanced Science ...my chemical biology research to chemical ...

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A chemical genomics approach to drug reprofiling in oncology : antipsychotic drug risperidone as a potential adenocarcinoma treatment

A chemical genomics approach to drug reprofiling in oncology : antipsychotic drug risperidone as a potential adenocarcinoma treatment

... Tag® chemical genomics tool and screened against a T7 bacteriophage displayed library of polypeptides from Drosophila melanogaster, as a whole genome model, to uncover an interaction with a section of ...

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A Chemical Genomics Approach to Drug Reprofiling in Oncology: Antipsychotic Drug Risperidone as a Potential Adenocarcinoma Treatment

A Chemical Genomics Approach to Drug Reprofiling in Oncology: Antipsychotic Drug Risperidone as a Potential Adenocarcinoma Treatment

... [9] P.C. Taylor, A.J. Clark, A. Marsh, D.R.J. Singer, S.J. Dilly, A chemical genomics approach to identification of interactions between bioactive molecules and alternative reading frame proteins, Chem. ...

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A plant-based chemical genomics screen for the identification of flowering inducers

A plant-based chemical genomics screen for the identification of flowering inducers

... to recombine the genomic AP1 fragment into the destina- tion vector pGREEN GW-FLuc, resulting in pAP1::AP1- FLUC in a pGREEN vector backbone. This vector was transformed to Agrobacterium tumefaciens C58, con- taining the ...

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Chemical genomics: what will it take and who gets to play?

Chemical genomics: what will it take and who gets to play?

... express well in Escherichia coli; others will require yeast, baculovirus, or even mammalian expression systems. Some proteins will tolerate amino-terminal tags (to allow them to be affinity purified); others will require ...

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Chemical Genomics: A Systematic Approach in Biological Research and Drug Discovery

Chemical Genomics: A Systematic Approach in Biological Research and Drug Discovery

... various chemical genomics ...that chemical ligands should become available for any given protein, which allows chemical modulation of the protein’s activity, both positively or negatively, and ...

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Autophagic inhibition via lysosomal integrity dysfunction leads to antitumor

Autophagic inhibition via lysosomal integrity dysfunction leads to antitumor

... 1 Chemical Genomics Global Research Laboratory, Department of Biotechnology, College of Life Science and Biotechnology, Yonsei University, Seoul 03722, Republic of Korea.. 2 Biomedical [r] ...

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Chemical genomic guided engineering of gamma-valerolactone tolerant yeast

Chemical genomic guided engineering of gamma-valerolactone tolerant yeast

... of chemical genomics with the yeast (Saccharomyces cerevisiae) deletion collection to identify sensitive and resistant mutants, and chemical proteomics to monitor protein abundance in the presence of ...

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Mechanism of imidazolium ionic liquids
            toxicity in Saccharomyces cerevisiae and rational
            engineering of a tolerant, xylose-fermenting strain

Mechanism of imidazolium ionic liquids toxicity in Saccharomyces cerevisiae and rational engineering of a tolerant, xylose-fermenting strain

... The fermentative capacity of the engineered, IIL-toler- ant yeast versus the parent strain is the best test of the chemical genomics-guided biodesign. Y133-IIL had greater growth and sugar conversion in the ...

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Known unknowns: building an ethics of uncertainty into genomic medicine

Known unknowns: building an ethics of uncertainty into genomic medicine

... In this paper, rather than looking at the actual impact of uncertainty, we focus on its normative status within genomic medicine. We ask: how should we conceive of and respond to ‘uncertainty’ in genomic medicine? Our ...

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Genomics and data science: an application within an umbrella

Genomics and data science: an application within an umbrella

... to genomics datasets. Most computa- tions in genomics data are hosted as FASTA/FASTQ, BED, BAM, VCF, or bigwig files, which respectively repre- sent sequences, coordinates, alignments, variants, and ...

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Whole Genome Sequence and Comparative Genomics Analysis of Multi drug Resistant Environmental Staphylococcus epidermidis ST59

Whole Genome Sequence and Comparative Genomics Analysis of Multi drug Resistant Environmental Staphylococcus epidermidis ST59

... Whole Genome Sequence and Comparative Genomics Analysis of Multi drug Resistant Environmental Staphylococcus epidermidis ST59 Whole genome sequence and comparative genomics analysis of multi drug resi[.] ...

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Whole Genome Sequence and Comparative Genomics Analysis of Multi drug Resistant Environmental Staphylococcus epidermidis ST59

Whole Genome Sequence and Comparative Genomics Analysis of Multi drug Resistant Environmental Staphylococcus epidermidis ST59

... parative genomics analysis are warranted to further our understanding of the origin and evaluation of multidrug resistant isolates from differ- ent ecological ...

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A Broadly Implementable Research Course in Phage Discovery and Genomics for First Year Undergraduate Students

A Broadly Implementable Research Course in Phage Discovery and Genomics for First Year Undergraduate Students

... and genomics are a plat- form that supports engagement of students in authentic research without requiring prior mastery of anything other than very basic concepts and content material ...Advancing Genomics ...

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Reports

Reports

... The IAL will hold its next quadrennial symposium in Bangkok on 9–13 January 2012 (<www.ial7.ru.ac.th/>) hosted by Ramkhamhaeng University. Most aspects of plant/microbial biology are represented amongst the session ...

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New life sciences innovation and distributive justice: rawlsian goods versus senian capabilities

New life sciences innovation and distributive justice: rawlsian goods versus senian capabilities

... The successful decoding of human genome and subsequent advances in new life sciences innovation create technological presuppositions of a new possibility of justice i.e. the just distribution of both social (income, ...

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An Update on Dairy Products Authenticity -Scientometric Evaluation and Prospects

An Update on Dairy Products Authenticity -Scientometric Evaluation and Prospects

... Dairy products authentication has become an emerging issue for the food industry, consumers and researchers worldwide. A scientometric evaluation that highlights research trends of this evolving field is presented. ...

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Whither genomics?

Whither genomics?

... from genomics must draw into our circle mathematicians, physicists, computer scientists and others who have thought hard about how to analyze enor- mous quantities of sparsely connected ...for genomics. ...

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Genomics and the Law

Genomics and the Law

... Given the fact that many advantages and disadvantages are not specific to the DNA (self)tests but also apply to screening, population screening and individual diagnostics, for the time[r] ...

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