chromatin conformation
Classifying leukemia types with chromatin conformation data
... structure-function, chromatin conformation and its molecular composition are thought to mutually affect each other to reach and propagate a given activity ...that chromatin conformation ac- ...
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Influence of oncogenic transcription factors on chromatin conformation and implications in prostate cancer
... with chromatin conformation, while emphasizing the TMPRSS2-ERG fusion, which is found in more than one-half of prostate cancer patients and its functions in compromising the chromatin landscape in ...
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4D nucleomes in single cells: what can computational modeling reveal about spatial chromatin conformation?
... chromosome conformation queries is the foreseen ability to re-order single-cell structures to infer a developmental path of changes in chromatin conformation—for example, as cells go through the cell ...
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Characteristics of the Adeno-Associated Virus Preintegration Site in Human Chromosome 19: Open Chromatin Conformation and Transcription-Competent Environment
... open chromatin conformation and hence is easily accessible to Rep proteins in vivo (9, 12, 53, ...the chromatin configuration in that region (17, 31, 32, ...
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Alu retrotransposons modulate Nanog expression through dynamic changes in regional chromatin conformation via aryl hydrocarbon receptor
... of chromatin loops suggests that this type of regulatory mechanism might be observed in other genes or ...in chromatin architecture could become a com- mon mechanism to downregulate or upregulate gene ...
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Chromatin Conformation of Integrated Moloney Leukemia Virus DNA Sequences in Tissues of BALB/Mo Mice and in Virus-Infected Cell Lines
... We observed that the pattern of DNase I digestibility of M-MuLV sequences in the chromatin of spleen and tumor celLs was very similar to that found in BALB/ Mo mice: in young animals car[r] ...
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Characterization of interleukin (IL)-1β regulatory elements and chromatin conformation in macrophage activation
... interactions has not yet been demonstrated, they are transcription co-factors that co- localize with pioneer factors and acetylate unique residues of histones [47,81]. Specifically, Whalen et al. exemplified the ...
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Studies on chromatin conformation of radiosensitive (xrs) Chinese hamster cell lines
... the chromatin such as relaxation of torsional tension that allows the DNA to be wound tighter (39,40) or accumulated ongoing ‘slow’ repair leading to an overall reduction of residual damage in hypertonic solutions ...
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Integrative prediction of gene expression with chromatin accessibility and conformation data
... matin conformation data, it has not yet been integrated into computational methods inferring gene expression using experimentally or computationally determined TF binding ...from chromatin ...
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GC and AT rich chromatin domains differ in conformation and histone modification status and are differentially modulated by Rpd3p
... in chromatin compaction or a difference in cross- linking efficiency, and the two possibilities can be distin- guished by assessing the efficiency of restriction ...the conformation of these GC-rich and ...
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Chromatin accessibility: a window into the genome
... Functional annotation of accessible regions is factor- dependent and relies highly on the availability of accur- ate TF binding motifs and their relevant information content as well as the spatial and temporal ...
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THE EFFECT OF MECHLOROETHAMIN ON RECONSTITUTED CHROMATIN
... reconstituted chromatin was prepared in the presence of various concentrations of ...alkylated chromatin had encountered difficulties in producing nucleosomes in comparison to the control (untreated ON ...
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Chromatin remodeling in plant development
... for chromatin-dependent regulation of FLOWER- ING LOCUS C (FLC) ...FLC chromatin might exist in at least three different configurations: the active state required for the establishment of the winter-annual ...
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CRANKITE: a fast polypeptide backbone conformation sampler
... To obtain the canonical ensemble of polypeptide confor- mations, we developed a novel Metropolis Monte Carlo procedure. Each new chain conformation was generated from the previous one by applying a move to a ...
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Chromatin Topology and Transcription in Myogenesis
... sheared chromatin isolated from Drosophila embryos from 1 to 3 h in age, using an antibody that is specific to Twist protein, and subsequently assessed the overlap between sets of regions identified by each ...
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Investigations of chromatin bound enzymes
... iihS JLTS AN11 DISCJdSIONS... and Davidson, I?.[r] ...
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Evaluation of the conformation of stallions of selected horse breeds
... the conformation of stallions of the breeds American Quarter Horse (AQH), American Paint Horse (APH), Appaloosa (Appa), the Lipizzaner horse (LH) and the Old Kladruby horse ...
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Resolving spatial inconsistencies in chromosome conformation measurements
... The algorithms for ConsP (MST-A DD and SP-U NION ) find graphs with far fewer edges and far lower total con- fidence than any of the solutions for ConsT (Figure 1), and they sacrifice a sig[r] ...
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Chromatin Remodeling Factors Isw2 and Ino80 Regulate Checkpoint Activity and Chromatin Structure in S Phase
... S. cerevisiae Isw2p is the ATPase subunit of the Isw2 chromatin remodeling factor involved in gene repression (Goldmark et al. 2000; Whitehouse et al. 2007). Nhp10p is a subunit of Ino80 that is known to exist ...
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Crystallisation and chain conformation of long chain n alkanes
... the conformation of the chains deposited on the growth ...extended conformation and the rate of crystallisation strongly ...chain conformation for different temperature regions is ...
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