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Coagulation and thrombus formation

Active site blocked factor IXa prevents intravascular thrombus formation in the coronary vasculature without inhibiting extravascular coagulation in a canine thrombosis model

Active site blocked factor IXa prevents intravascular thrombus formation in the coronary vasculature without inhibiting extravascular coagulation in a canine thrombosis model

... studied. Thrombus formation was initiated by applying current to a needle in the circumflex coronary ...fibrin/platelet thrombus in 70 +/- 11 ...prevented thrombus formation completely ...

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Thrombus formation in vivo

Thrombus formation in vivo

... blood coagulation and thrombosis has moved through many ...of thrombus morphol- ogy and pathology were followed by a period in which blood coagulation proteins were identified based on the character- ...

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Giant left atrium associated with massive thrombus formation

Giant left atrium associated with massive thrombus formation

... of thrombus in our patient was huge in com- parison to previously reported cases despite the fact, that the size of the left atrium in our patient was ...anti- coagulation and without any evidence of ...

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Tie2 protects the vasculature against thrombus formation in systemic inflammation

Tie2 protects the vasculature against thrombus formation in systemic inflammation

... and coagulation parameters, network analysis of the proteomics strongly implicated the endothelium, including alterations in the endothelial regulatory angiopoietin-1 (Angpt-1)/Tie2 signaling ...precipitates ...

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Endogenous Fibrinolysis : An Important Mediator of Thrombus Formation and Cardiovascular Risk

Endogenous Fibrinolysis : An Important Mediator of Thrombus Formation and Cardiovascular Risk

... There are a number of important limitations to the use of TEG as a clinical tool to assess global throm- botic status. TEG was originally designed for native, nonanticoagulated blood (47) , but subsequent modi- fications ...

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Flow effect on thrombus formation in stenosed coronary arteries: a computational study

Flow effect on thrombus formation in stenosed coronary arteries: a computational study

... production of the correct amount of substance but the value of the concentration would be grid dependent while with the second formulation we would have correct bulk concentration values but the total amount of the ...

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Tyro3, Axl, and Mertk receptors differentially participate in platelet activation and thrombus formation

Tyro3, Axl, and Mertk receptors differentially participate in platelet activation and thrombus formation

... 8. Tanabe K, Nagata K, Ohashi K, Nakano T, Arita H, Mizuno K. Roles of gamma- carboxylation and a sex hormone-binding globulin-like domain in receptor- binding and in biological activities of Gas6. FEBS Lett. ...

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Atrial Fibrillation-Associated Remodeling Does Not Promote Atrial Thrombus Formation in Canine Models

Atrial Fibrillation-Associated Remodeling Does Not Promote Atrial Thrombus Formation in Canine Models

... Novel Aspects and Potential Significance There are no published experimental studies of the effect of atrial remodeling on atrial thrombus formation. Although pre- vious studies point to an increased ...

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In Vitro Evaluation of Intra Aneurysmal, Flow Diverter Induced Thrombus Formation: A Feasibility Study

In Vitro Evaluation of Intra Aneurysmal, Flow Diverter Induced Thrombus Formation: A Feasibility Study

... the thrombus formation because fibrin- and platelet-rich thrombi were present on the FD surface before any thrombus in the aneurysm was ...of thrombus formation because the thrombi ...

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Segmentation, Reconstruction, and Analysis of Blood Thrombus Formation in 3D 2-Photon Microscopy Images

Segmentation, Reconstruction, and Analysis of Blood Thrombus Formation in 3D 2-Photon Microscopy Images

... of thrombus growth and ...of coagulation factor VII) and analyze and compare the developing clot structures based on their reconstructed clots from image ...the thrombus development, and is valuable ...

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Thrombus formation and platelet vessel wall interaction in the nephrotic syndrome under flow conditions

Thrombus formation and platelet vessel wall interaction in the nephrotic syndrome under flow conditions

... 1. Coagulation and thromboembolic complications in the nephrotic syndrome. Hypercoaguability, renal vein thrombosis and other throm- botic complications of nephrotic syndrome. The pathog[r] ...

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Evaluation of the Total Thrombus-Formation System (T-TAS): application to human and mouse blood analysis

Evaluation of the Total Thrombus-Formation System (T-TAS): application to human and mouse blood analysis

... vivo thrombus formation in small animal ...testing thrombus formation in mouse blood, we first analysed blood samples from WT ...total thrombus formation compared to human ...

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Investigating novel platelet immunoreceptor ‘CEACAM2’ in contact-dependent events that modulate platelet thrombus formation

Investigating novel platelet immunoreceptor ‘CEACAM2’ in contact-dependent events that modulate platelet thrombus formation

... localised thrombus formation via the adhesion of platelets to exposed subendothelial matrix components in vascular ...pathological thrombus formation, two methods for inducing arterial injury ...

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Stabilizing role of platelet P2Y(12) receptors in shear-dependent thrombus formation on ruptured plaques

Stabilizing role of platelet P2Y(12) receptors in shear-dependent thrombus formation on ruptured plaques

... in thrombus stabilization was confirmed by in vitro flow studies using either mouse or human ...when coagulation was introduced, blockage or deficiency of P2Y 12 suppressed the formation of larger ...

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Intra cardiac thrombus resolution after anti coagulation therapy with dabigatran in a patient with mid ventricular obstructive hypertrophic cardiomyopathy: a case report

Intra cardiac thrombus resolution after anti coagulation therapy with dabigatran in a patient with mid ventricular obstructive hypertrophic cardiomyopathy: a case report

... aneurysm formation was observed at the left ventricular apex (Figure 1), and technetium (99mTc) tetrofosmin single- photon emission computed tomography demonstrated severe hypoperfusion in this area (Figure ...

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Molecular imaging of atherosclerosis and thrombus formation

Molecular imaging of atherosclerosis and thrombus formation

... the formation of the necrotic core and weakening of the overlying fibrous cap, this annexin A5- functionalized nanoparticle could aid in the assessment of ...of thrombus formation as PS is also ...

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THE ACCELERATION OF THROMBUS FORMATION BY CERTAIN FATTY ACIDS

THE ACCELERATION OF THROMBUS FORMATION BY CERTAIN FATTY ACIDS

... Thus, oleic and linoleic, as prototypes of long chain, unsaturated fatty acids, and caproic and octanoic, as examples of short chain, saturated fatty acids, probably did not accelerate t[r] ...

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Trihalomethane Formation Potential in the Water Treated by Coagulation

Trihalomethane Formation Potential in the Water Treated by Coagulation

... The water after collection was transported to the laboratory and stored until the following day at a temperature of 4°C. For the execution of the coagulation process, a coagulator with mechani- cal stirrer and ...

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PKCα regulates platelet granule secretion and thrombus formation in mice

PKCα regulates platelet granule secretion and thrombus formation in mice

... In summary, we have shown PKCα to play major roles in regu- lating platelet secretion of α-granules, biogenesis and secretion of dense granules, regulation of integrin α IIb β 3 , and thrombus formation in ...

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DIET AND THROMBUS FORMATION: QUANTITATIVE STUDIES USING AN EXTRACORPOREAL CIRCULATION IN PIGS

DIET AND THROMBUS FORMATION: QUANTITATIVE STUDIES USING AN EXTRACORPOREAL CIRCULATION IN PIGS

... Similar results were revealed by comparison of the weight of deposit formed in the extracorporeal shunts, a mean weight of deposit lower in the control group than in the other groups (p [r] ...

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