Codon Bias
The Relationship Between Third-Codon Position Nucleotide Content, Codon Bias, mRNA Secondary Structure and Gene Expression in the Drosophilid Alcohol Dehydrogenase Genes Adh and Adhr
... between codon bias, mRNA secondary structure, third-codon position nucleotide distribution, and gene expression, we predicted secondary structures in two related drosophilid genes, Adh and Adhr, ...
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The Relation of Codon Bias to Tissue-Specific Gene Expression in Arabidopsis thaliana
... observed codon bias. Sémon et al. (2006) argued that differences in codon bias among tissue-specific genes were driven by mutational biases that act on the GC content of genes, rather than ...
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Dietary nitrogen alters codon bias and genome composition in parasitic microorganisms
... of codon usage at those sites ...in codon bias between genes due to gene-specific selective pressures such as splice site conservation, mRNA stability, ribosome binding and mRNA ...
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X-Linked Genes Evolve Higher Codon Bias in Drosophila and Caenorhabditis
... the codon bias of an individual gene such as protein length, GC content, and expression ...increases codon bias, we sampled autosomal genes to match the distribution of X-linked genes with ...
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Rare codon content affects the solubility of recombinant proteins in a codon bias-adjusted Escherichia coli strain
... To determine the levels of expression and the amount of soluble protein, induction of expression of all proteins under study was performed in both strains using identical conditions as described in Methods and compared ...
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Codon bias patterns in photosynthetic genes of halophytic grass Aeluropus littoralis
... 60% codon bias in all studied genes This indicates the high levels of gene expression and requires the use of optimal codons of these genes (Table ...between codon bias and gene expression ...
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Codon bias and the folding dynamics of the cystic fibrosis transmembrane conductance regulator
... in codon bias in these regions, especially at helices entering or leaving the membrane introduced by mutations or sSNPs could affect CFTR folding efficiency significantly and thus the levels and/or function ...
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Analysis of Gene Expression using Modified Relative Codon Bias Strength in Nanoarchaeum Equitans
... extreme codon bias towards the use of optimal set of codons and based on this hypothesis, several codon usage indices are used to predict gene expressions in different ...a codon usage ...
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Codon bias of influenza a viruses and their hosts
... synonymous codon us- age bias indexes (GC content, ENC, SCUO, Codon Volatility, RSCU, and Odds Ratio), this study re- vealed the evolutionary drift patterns in the Influ- enza A viruses of avian, ...
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Use of a naturally occurring codon bias for identifying topoisomerase mutations in ciprofloxacin resistant Escherichia coli using PCR and future prospects with other bacterial genera: A pilot study
... native codon sequence or PAN PCR. By this method, only the native codon se- quence is amplified in a PCR reaction while a mutated sequence will ...occurring codon bias in ...such codon ...
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Codon Bias Differentiates Between the Duplicated Amylase Loci Following Gene Duplication in Drosophila
... sites Codon usage bias (effective number of codons [ENC]; between them is due to the change of selection intensity Wright 1990) and GC content at synonymous third codon position was computed using ...
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The effects of mutation and natural selection on codon bias in the genes of Drosophila.
... In contrast, no G + C correlation was found be- tween introns and third codon positions of fourfold de- generate codons in highly biased genes, consistent with an overriding[r] ...
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Selection intensity for codon bias.
... Among the codon positions at which the amino acid is conserved in the two species, some positions also use identical codons, whereas other positions use synonymous codons, and the[r] ...
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Does codon bias have an evolutionary origin?
... Results: Codon Usage Bias (CUB, defined here as deviation from equal usage of synonymous codons) was studied in 113 ...Pan-Genomic Codon Usage Frequency (CUF) Table was constructed to describe ...
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Site-Specific Codon Bias in Bacteria
... frame) is not avoided, it seems that selection acts during translation. Site-specific preferences be- tween C and T at synonymous sites are harder to ex- plain. Almost always,[r] ...
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In Vivo Introduction of Unpreferred Synonymous Codons Into the Drosophila Adh Gene Results in Reduced Levels of ADH Protein
... of codon bias, the unequal usage of synonymous codons, is thought to be due to natural selection for the use of preferred codons that match the most abundant species of isoaccepting tRNA, resulting in ...
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Synonymous Codon Usage in Bacteria
... if codon bias between leading and lagging strand is ...in codon usage that make values of CAI higher for some genes, and the method does not give any guidance as to how to distinguish random ...
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Protein Evolution and Codon Usage Bias on the Neo-Sex Chromosomes of Drosophila miranda
... Reduced codon bias in the D. miranda lineage: In contrast to the striking difference between the neo-X and neo-Y in patterns of protein evolution, unpreferred synonymous substitutions do not accumulate ...
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Reduction of the Rate of Poliovirus Protein Synthesis through Large-Scale Codon Deoptimization Causes Attenuation of Viral Virulence by Lowering Specific Infectivity
... a codon-deoptimized virus does succeed in disabling the cell, this virus will produce nearly identical amounts of progeny to the wild ...of codon-deoptimized ...suboptimal codon usage as the PV ...
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Long-Term Evolution and Functional Diversification in the Members of the Nucleophosmin/Nucleoplasmin Family of Nuclear Chaperones
... While the NPM2 protein N-terminal folded regions are subject to critical structural constraints, the post- translational phosphorylation of serine, threonine, and tyrosine residues at the N-terminal exposed regions of ...
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