Colon Targeting
COLON TARGETING MICROSPHERE: A REVIEW
... of colon specific drug delivery ...the colon like cancer,Crohn’s disease, ulcerative colitis, etc but also for the systemic delivery of proteins, therapeutic peptides, anti-asthmatic drugs, antihypertensive ...
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<p>Colon Targeting of Naringin for Enhanced Cytoprotection Against Indomethacin-Induced Colitis in Rabbits</p>
... and colon into its aglycone, ...for colon targeting to attain high drug concentrations in the colon and allow the hydrolysis to its aglycone naringenin for providing cytoprotection against ...
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DEVELOPMENT AND INVESTIGATION OF EUDRAGIT S 100 ENCAPSULATED CHITOSAN COATED LIPOSOMES OF PREDNISOLONE FOR COLON TARGETING
... ABSTRACT: The objective of the study was to formulate coated liposomes containing Prednisolone for colon targeting and localization of the therapy to the inflamed colon mucosa. Liposomes were ...
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Formulation, Evaluation and Colon Targeting of 5-Fluorouracil Nanoparticles Using PH Sensitive Polymer
... reviewed colon-targeted delivery of bioactives has recently gained importance in addressing specific needs in the therapy of colon- based ...of colon-specific delivery systems, with not much success ...
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Development and evaluation of pH-dependent micro beads for colon targeting
... system. Colon targeting has been achieved by several ways, which include prodrugs, pH- and time-dependent ...for colon specifi c drug delivery. To achieve successful colon drug delivery, a ...
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OPTIMIZED DEVELOPMENT AND EVALUATION OF MICROBIALLY TRIGGERED BASED ORNIDAZOLE MICROSPHERES FOR COLON TARGETING
... based colon targeted microspheres using two carriers tragacanth gum and inulin individually which would protect the release of the drug in the physiological environment of the stomach and small intestine and ...
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PREPARATION AND EVALUATION OF METRONIDAZOLE MATRIX TABLETS FOR COLON TARGETING
... the colon which includes pH- dependent delivery systems, time-dependent delivery systems, microbially-controlled delivery systems, pressure-dependent delivery systems, enzyme-based delivery ...for colon ...
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NEW POLYMERIC FILM COATING FOR COLON TARGETING AND IT'S EVALUATION
... For colon targeting delivery, various concentrations of the mixture of water soluble (Guar gum) and water insoluble (Cellulose Acetate) polymers were used to prepare the coating ...
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METRONIDAZOLE LOADED EUDRAGIT COATED ALGINATE BEADS FOR COLON TARGETING
... Use of high molecular weight polysaccharides like alginate, pectin, guar gum, chitosan etc. have mostly been limited to pharmaceutical aids except for the colon targeting since last two decades. Various ...
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STUDY OF ENTERIC COATED SODIUM ALGINATE MICROSPHERE OF AZATHIOPRINE FOR COLON TARGETING
... The increase in incidence and prevalence of IBD over the last 15 years and its prevalence in most of the developing countries give the tremendous opportunity for the researchers to develop a colon-specific ...
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A double prodrug system for colon targeting of benzenesulfonamide COX 2 inhibitors
... In order to examine both of the necessary mechanistic components of drug release i.e. azo reduction and cyclization, 2 was incubated under anaerobic conditions in a brain-heart- infusion (BHI) suspension that had been ...
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POLYSACCHARIDE MICROSPONGE BASED MATRIX TABLET FOR COLON TARGETING OF KETOPROFEN: IN VITRO AND IN VIVO EVIDENCE
... ABSTRACT: The present research was aimed to formulate erosion based matrix tablets of ketoprofen micro-sponges for spatial-colon targeting. For the optimization, the effects of independent variables like ...
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Enzyme Specific Drug Delivery System: A Potential Approach for Colon Targeting
... in colon-specific delivery systems by reacting toluene-2, 6- diisocyanate with a mixture of an aromatic azo diol, (bis-4- hydroxyphenyl)-4, 4' diazobiphenyl, poly (ethylene glycol) and 1, 2-propanediol (propylene ...
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Formulation and evaluation of sulfasalazine tablets for colon targeting using 33 response surface method
... develop colon targeted tablets of Sulfasalazine (SSZ) by wet granulation method using 3 3 Response surface method with Design of experiment software and Eudragit RS 100, Eudragit RL 100-55, Ethyl cellulose and PVP ...
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DESIGN AND DEVELOPMENT OF METOPROLOL SUCCINATEPULSINCAP TECHNOLOGY CHRONOTHEREPEUTIC SYSTEM USING NATURAL GUM AS A MATERIAL FOR COLON TARGETING
... reach colon and thus this system can be considered as one of the promising formulation technique for preparing colon specific drug delivery systems and hence in the chronotherapeutic management of Angina ...
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FORMULATION, DEVELOPMENT AND IN VITRO RELEASE EFFECTS OF ETHYL CELLULOSE COATED PECTIN MICROSPHERES FOR COLON TARGETING
... degradation. This natural polymer is also appealing for use in drug delivery for a wide range of molecular weights, varying chemical compositions, low toxicity and biodegradability. Therefore more research is necessary ...
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A novel folate-modified self-microemulsifying drug delivery system of curcumin for colon targeting
... amount was released from the capsule in the following 3 hours and (in simulated intestinal fluid with pH 6.8), about 13% of curcumin was released from the capsule. In conclusion, in the first 5 hours, less drug was ...
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FORMULATION AND INVITRO EVALUATION OF BUDESONIDE MICROSPHERES FOR COLON TARGETING
... INTRODUCTION: Colon was considered as a part of body solely responsible for absorption of water, electrolyte and temporary storage of stools, but now it is accepted as an important site for drug ...Drug ...
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Polysaccharides for Bacterially Triggered System in Colon Targeting
... only colon- specific delivery systems but also delayed-release system of certain drugs 102, 103 ...or colon, whereas no appreciable drug release was observed on incubation with the contents of either ...
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NANOPARTICLES OF ATORVASTATIN A NOVEL WAY OF COLON TARGETING
... The present study involves the formulation, optimisation and evaluation of Atorvastatin loaded chitosan nanoparticles by ionotropic gelation method using sodium tripolyphosphate as ionic cross-linker and enteric coating ...
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