Computational methods for functional annotation of genes
Original Article A database and functional annotation of NF-κB target genes
... and functional annotation of NF-κB target genes. Methods: In this study, we manually collected the most complete listing of all NF-κB target genes identified to date, including the ...
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A prioritization analysis of disease association by data-mining of functional annotation of human genes
... candidate genes for PC, may be a reasonable candidate ...related genes for RA and PC again with new ...40 genes were newly described as RA-related genes in the OMIM database (Supplemental ...
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Experimental and computational methods to assign gene function to maize genes
... RefGen_v3 annotation set 5b+ using only experimentally- based annotations by filtering out GO assignments with IEA, NAS, and ND ECs from the input data and assigned GO terms using multiple input datasets then ...
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Functional Annotation of Genes Overlapping Copy Number Variants in Autistic Patients: Focus on Axon Pathfinding
... affect genes involved in synapse formation and function [2, 4, 41, ...analyses, genes overlapping CNVs detected in autistic patients have been annotated to a variety of func- tional categories including ...
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Exome-wide search and functional annotation of genes associated in patients with severe tick-borne encephalitis in a Russian population
... additional methods to analyze our unique ...the functional annotation and analysis of PPIs for (1) genes, harboring rare harmful variants in TBE patients only (cases_only set, Additional file ...
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The duplicated genes database: identification and functional annotation of co-localised duplicated genes across genomes
... the genes are not included in any co-localised and duplicated ...duplicated genes is selected, each gene is described by name (HGNC), by chromosome and by base pair ...between genes in biological ...
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Functional Annotation of Cotesia congregata Bracovirus: Identification of Viral Genes Expressed in Parasitized Host Immune Tissues
... virulence genes have been studied in cater- pillar ...wasps. Genes for which expression could be detected corresponded to genes localized in par- ticular regions of the viral genome globally ...
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Combining Genome-Scale Experimental and Computational Methods To Identify Essential Genes in Rhodobacter sphaeroides
... Workflow for Tn-seq data analysis. By leveraging the random insertion of trans- posons into a genome, Tn-seq can identify essential genes and the fitness contributions of nonessential genes on a genomic scale ...
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Computational Methods for Annotation Transfers from Sequence
... of computational methods for pro- tein function ...orthologous genes as described above, but also further patterns indicative of functional linkages between gene pairs such as fusion events, ...
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Computational Methods for Annotation Analysis of Genetic Variations
... elements, genes being the most important ...bioinformatics methods and common annotation terms were created to help reference specific biologic or molecular properties, processes, functions, ...
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Development of computational methods for analysing proteomic data for genome annotation
... novel genes that were identified by the MS analysis pipeline with high ...validating genes and gene structures, while also highlighting the theoretical limitations of this ...genome annotation and it ...
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Computational Techniques for the Functional Annotation of Hypothetical ORFS in Human Chromosome 3
... such genes is not known. Despite several efforts, only 50-60 % of genes have been annotated in most completely sequenced genomes and their functions are ...the genes in any genome is totally unknown ...
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Nuclear Magnetic Resonance Affinity Screening Methods for Functional Annotation of Proteins and Drug Discovery
... silencing methods using antisense oligodeoxynucleotides, 34 ribozymes 35 or RNA interference 36-38 and recently metabolomic ...essential genes are relatively straightforward with the appropriate control ...
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Structural and functional annotation of the porcine immunome
... term annotation enrichment related to immune ...immune-related genes such as IL15, JAK2, IRF2, IRF7, IRF9, IFIT 1, IFIT2, IFIT3, CD40, CD47, CD86, many STAT, PSMB and CASP gene family mem- bers, MX1, MX2, ...
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Functional Annotation of the Bovine and Porcine Genomes
... ten genes with the most nsSNPs are shown in Table 11. These genes typically encode very large proteins and are not necessarily unusually ...between genes, ranging from one nsSNP every 20 bases to one ...
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Computational Methods in Metabolomics
... Diverse health challenges such as rising incidence of metabolic disease, rapid ag- ing, and increasing antibiotic resistance are facing current humanity. Most diseases involve many genes in complex interactions, ...
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radiotherapy by computational methods
... gene and NCG - total number of target genes that must be damaged to induce genomic instability) after irradiation with different irradiating agents are shown in Fig. 4a. Statistical analysis showed significant ...
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Identification and Functional Annotation of Alternatively Spliced Isoforms
... from genes generating multiple protein-coding splice variants ...multiexonic genes in multicellular ...the functional dynamics of splice variants in different tissues and ...modeling methods ...
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Biotechnological Advances in Methods for Functional Analysis of Genes
... Illumina methods in that it relies upon sequencing by ligation in which the sequence of a DNA template is read by competitive ligation of 2-base probes to the nascent DNA strand (Rothberg & Leamon ...
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Discovery of functional miRNA–mRNA regulatory modules with computational methods
... a computational method for identifying functional regulatory miRNA–mRNA modules using predicted miRNA targets as well as expression profiles of miRNAs and ...
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